Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16273 Mitoxantrone GSE70138 MCF10A Human 24h 0.37uM EID0005
Types Number Response transcription factors
Up-regulation 58 SREBF2; MXD4; PBXIP1; TRIM22; CALCOCO1; ZMYM2; ZNF536; DLX4; ZNF226; RUNX1; PNRC1; JUN; TFEC; NFE2L1; MEF2A; EPAS1; MAF; SMARCA1; NAB1; AHR; ELF1; MNT; TADA3; ATF3; BAZ2B; CUX1; TRIM29; IRF9; NR4A2; KDM5B; MXI1; HDAC9; COPS2; FOXF2; TAF1D; ZNF281; LPIN2; JUNB; BTG1; ESR1; ZNF415; BASP1; CREM; TBX2; PDLIM1; SNAI2; JUP; STAT1; ERBB4; CD3D; MEIS1; MNDA; TOX3; HOXD1; GATA6; BCL3; TSC22D1; FOS
Down-regulation 89 CCNA2; FOXM1; TFDP1; EZH2; HMGB2; CENPF; TAF9B; WDHD1; YEATS4; DNMT1; MYBL2; BAZ1B; RBL1; ZNF586; CDK2; GMNN; RNF138; WHSC1; TBL1XR1; DEK; TBPL1; ZNF551; BLM; PTTG1; RBBP4; HMGA1; CCNC; TAF1A; BRIP1; TTF1; WWTR1; ARNTL2; HMGB1; E2F8; TAF5; NFIB; FOXE1; UBE2I; NUP62; ITGB3BP; BRD7; UBE2B; BRCA1; ZNF273; TEAD4; CCDC59; SUB1; ING1; ZFHX4; TDRD3; TFAM; SAP30; PRKDC; CARHSP1; NFYB; KLF5; PITX2; HOXC10; IRF2; ILF2; TWIST1; BCLAF1; CBFB; BRCA2; ACTL6A; ZNF217; HNRNPD; ZHX2; SHOX2; HOXC6; SP3; BCL11B; HHEX; MYBL1; YWHAB; EGR3; NANOG; RBPMS; ELK3; SUV39H1; ZIC1; ID4; TLE4; VPS72; CREB1; ID1; MEIS2; KDM5D; MAFB