Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16272 Mitoxantrone GSE70138 MCF10A Human 24h 1.11uM EID0005
Types Number Response transcription factors
Up-regulation 213 IRF9; CALCOCO1; TRIM22; GLI2; ZNF665; MDM2; ZNF268; ZNF611; PBXIP1; SOX4; RING1; ZNF337; SUPT6H; GLI1; ZNF195; CDIP1; MZF1; SUPT7L; ZNF44; ZNF91; ADRB2; JUN; TRIM29; NFKB2; ARID5B; NR1H2; CBX7; EP300; SP110; ZNF160; PNRC1; ATF3; BNC2; ZNF264; ZNF304; ZNF606; IRF8; ZSCAN9; ZNF133; ZNF14; CREBL2; JUP; ZNF331; TP63; ZMYND8; EZH1; SRCAP; PPP1R13L; KAT6B; TBX10; ZNF224; DLX5; ELF4; LZTR1; SIN3B; SP100; MXD4; ZNF136; ZBTB43; ZNF536; ZNF768; NR5A1; CBX4; TCF4; THAP4; DYRK1B; REL; SKI; L3MBTL1; ZKSCAN4; TDP2; AES; ZNF426; ZNF358; BCL6; IRF7; BTG1; SIRT2; ZNF415; ZNF43; TCEB2; RUNX1; ZNF688; TSG101; DLX4; MED13; MEF2C; CERS4; ZNF444; IRF6; MAF; FOSL2; SNAI2; SPI1; OVOL2; RARG; ZBTB44; PRPF6; PRDM2; PEX14; NFIX; FOXF2; HBP1; TBX1; ZNF3; WNT4; ZNF512B; MITF; PLAG1; ZNF140; MNT; ZNF12; NKX2-1; ZNF85; ZKSCAN1; HDAC5; MEIS1; TFAP2A; ING4; MECOM; ZBED2; TWIST1; CHD9; ZBED1; ZBTB38; TLE2; ZNF500; ZNF587; KLF13; ZNF430; ZKSCAN7; NPAS2; ZBTB20; TXNIP; TOX; SALL2; TERF1; ZNF117; ZNF345; ERBB2; JUNB; BRWD1; SOX3; CUX2; SOX9; BAZ2B; SMARCC2; SOX2; KLF5; FLNA; ZNF623; TGFB1; CHD3; SCAND1; RBPJ; ZSCAN31; ESR1; HOXB13; NHLH2; ZNF93; HOXB5; HDAC9; ECD; CHD8; HMBOX1; PCGF2; TBX3; TCEA2; NCOA2; SOX17; LOXL2; ETV5; ZNF711; TRIM16; TOX3; ERBB4; NR4A2; HOXB2; TULP3; NCOR2; ELF3; DACH1; BRD4; FOSB; NR4A1; SMARCA1; ZSCAN18; MEIS2; TFAP2C; PBX1; FOXF1; ID1; HLF; HMGN3; ZNF589; BHLHE41; BCL11A; ARNT2; ETS2; ZFPM2; ZNF423; BCL3; GATA6; CREB1; NFATC4; ID3; KLF4; KLF11; FOS; VPS72; FOXO4; PEG3; KDM5D
Down-regulation 108 CCNA2; TFDP1; EZH2; FOXM1; CENPF; MYBL2; HMGB2; PARP1; MYC; PCBD1; CBX5; PSMC3IP; TCERG1; HMGA2; BRCA1; RHOA; HOXC6; YEATS4; PA2G4; TBL1XR1; RNF138; DEK; CHAF1B; RBBP4; NFIB; BLM; SAP30; BRD3; SMARCC1; CCDC59; RBL1; NUP62; PTTG1; TBPL1; CDK2; WHSC1; CBFB; SSRP1; RUVBL2; NR2F2; TAF5; RBM14; ITGB3BP; GMNN; BCLAF1; MAX; C1QBP; AGO2; TFAM; RAN; BRIP1; HOXC10; EED; TBL1X; RBPMS; CHD7; HMGB1; SFPQ; SUB1; HOXA10; HIPK3; YAF2; TRIM28; NPM1; PSIP1; HMGA1; MTDH; ATF1; HSF2; SPEN; CCNC; TAF9; HDGF; HNRNPD; NR1H3; CALR; ATF5; SMAD5; NFYB; SUV39H1; TRRAP; TAF9B; WWTR1; CITED2; JARID2; SMARCE1; PRKDC; ELF5; HOXC4; CEBPZ; KLF2; REST; CEBPG; BMI1; CBX3; ZBTB18; E2F8; SMAD1; HOXB7; DNMT3B; FOXD1; NR2F1; FOXJ3; ZNF22; CTBP2; ELK3; PPARG; MAFB