Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16270	Mitoxantrone	GSE70138	MCF10A	Human	24h	10uM	EID0005

Response Information :

Types	Number	Response transcription factors
Up-regulation	111	GLI2; CALCOCO1; IRF9; PBXIP1; IRF7; RFX5; TRIM22; NFKBIA; EP300; MXD4; ZNF611; ZNF195; MZF1; CDIP1; DMTF1; SP110; SUPT6H; MDM2; TLE2; TSG101; ARID5A; IRF3; HOXD1; ZNF160; HBP1; SRCAP; TRIM29; CIC; MED12; MNT; SOX15; TSC22D3; ZNF688; EZH1; SMARCD3; CBX7; PRMT2; HDAC5; TP63; NFIX; FLNA; ZNF768; ING4; ZBED2; SNAI2; HOXB1; SIN3B; ZNF536; AES; PNRC1; ZBTB17; MED13; KLF13; JUP; RUNX3; SP100; TBX1; PRDM12; NFKB2; NKX2-1; NCOA2; TRIP6; BNC1; ATF3; RARG; ZNF532; HLF; TBX21; SOX9; ZNF264; CERS4; HTATIP2; CREB5; HOXB13; SOX2; CREBL2; ZNF512B; JUN; SALL2; KLF6; BNC2; IRF6; ERBB2; NCOR2; LPIN2; MXI1; DLX5; BCL6; BCL3; IFI16; EYA1; CUX2; ZNF652; BRD4; ZIC1; TCF4; TGFB1; ZFP36L1; ZSCAN18; HMGN3; MEIS1; VPS72; SCAND1; TFAP2C; MAF; RELB; EGR2; MYRF; BHLHE41; ARNT2; ID1
Down-regulation	87	CCNA2; EZH2; TFDP1; CENPF; FOXM1; MYBL2; DEK; HOXA5; HMGB2; DNMT1; CCDC59; TAF5; YEATS4; CDK2; CEBPD; PA2G4; NFIL3; GMNN; HOXB7; BCLAF1; HDAC2; BRCA1; PSMC3IP; TFAM; CBX5; HOXC6; NR2F6; PTTG1; SSRP1; RBL1; WHSC1; HSF2; MED27; WWTR1; TAF9B; RNF138; RBBP4; ZNF184; IKZF5; ATF1; CHD7; BLM; TULP4; ELF2; TTF1; UBE2I; ING3; RUVBL2; TP53; HNRNPD; ISL1; RB1; PRKDC; CEBPG; E2F8; RBBP7; AGO2; HMGA1; BRD3; YAF2; BAZ1A; SAP30; CBX3; CBFB; ELF5; HIPK3; ITGB3BP; ZEB1; HMGB1; ZNF443; TRIB3; RAD21; NFIB; CALR; FOXD1; ARID4B; DDIT3; SUB1; HES1; SUV39H1; NR2F2; YWHAB; ZBTB18; LEF1; SATB1; MYB; CREB1