Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16253 As-601245 GSE70138 MCF10A Human 24h 10uM EID0005
Types Number Response transcription factors
Up-regulation 699 PAX8; NR6A1; ZNF117; ZNF586; ZNF304; ZNF816; ZBTB48; ASCL3; CIITA; RFX1; THRB; ZNF665; ERBB4; RING1; CALCOCO1; ZNF671; ZNF701; RFX3; E2F2; ESR1; ZNF154; LHX3; PRDM14; PHF1; ZNF43; NRL; SALL2; HBP1; ZBTB44; ZNF507; GLI2; ZSCAN2; HIRA; NFKBIB; SHOX; SCAI; NR5A1; ZNF350; ZNF770; EMX1; AR; RBPJL; TULP2; IKZF2; NR1H2; ZNF253; ZNF239; ZNF814; MED31; FOXH1; ZNF235; ZNF180; NEUROG1; POU6F1; MZF1; SOX5; HNF4G; ZNF135; LMX1B; ZNF221; PAX1; CDIP1; AFF2; PRDM9; ZKSCAN8; HINFP; CHD2; ZNF257; HOXB1; ZBTB3; SOX18; ZNF331; ZNF8; NEUROD6; ZNF223; NR5A2; ALX3; ING4; ZNF550; CDX4; ZNF345; POU6F2; ZNF606; ZNF695; CARF; PRDM1; ZIC3; HAND1; ZNF688; ZNF85; TBR1; ZNF667; TBX5; ZIC4; ZNF571; ZKSCAN4; ZIM2; TFDP2; ZFP2; TBX6; MAK; ZNF76; FEZF2; MEF2C; ZNF682; MDM4; SOX17; SPI1; SP4; ZKSCAN3; TSHZ2; HES2; ZNF91; NR1I3; MAML3; GATA2; ATOH1; FOXE3; ZNF250; PRDM2; ZNF442; GRIP1; ZNF268; EGR1; ZFPM2; EYA3; ONECUT1; SSX7; ARID5B; CRX; ZNF573; WHSC1L1; SSX3; NEUROD4; STAT2; SOX21; RORC; DCC; ZNF75D; ESRRB; TEF; VENTX; SOHLH2; ZNF506; ZNF528; NEUROG3; LZTR1; PPARA; ZNF142; IKZF3; NEUROD1; ZNF136; SSBP3; HNF4A; SOX3; ZNF549; PROP1; NR0B2; SCRT1; ZNF835; ZNF391; HESX1; HOXC8; BARX1; ZNF529; ALX4; ZNF195; ZNF467; ZNF208; ZNF132; NHLH1; PAX7; NAB2; ZNF510; GFI1B; ZNF544; ZNF273; SIX6; NEUROD2; ZNF500; HOXB8; CBFA2T3; ZBTB43; VGLL1; ZNF140; NKX3-2; RORB; CBX2; CSDC2; SRY; HIF3A; POU2F3; HDAC9; TFDP3; RFX2; ZNF274; HDAC5; IRF9; CDX1; EP300; ZNF536; CIR1; BRWD1; BNC2; TLX1; NEUROG2; E4F1; PAX4; ZNF749; TBX4; ZNF224; GBX1; ZFHX2; ATF2; PAX3; WT1; L3MBTL1; ZNF141; OVOL1; CCNH; MED12; ZNF264; ZNF484; LBX1; MECP2; ZNF362; TBL1Y; ZNF613; SHOX2; ZNF493; ESR2; TP73; PRDM16; WNT4; ZNF225; CD3D; HOXD12; FOXD3; ZNF675; KLF8; TAF6L; FOXN1; MAPK8IP1; SKI; GSC2; HHEX; MYCL; THRA; KLF15; TWIST1; ZNF184; DLX4; CAMTA2; GATA1; ZBED2; ZBTB7B; KLF13; ZNF215; ZFP30; ARID3B; CREB3L2; KMT2D; LIN28A; PDX1; NACA2; POU1F1; TBX19; TAF1C; E2F4; NFE2; SOX1; ZNF33B; ZNF415; HOXD3; PRDM5; POU3F3; ZNF254; MAP3K10; TLX2; ETV2; TFEC; NFIX; ZNF492; ZNF14; PRDM12; NCOA3; AFF3; ZSCAN32; PNRC1; ZNF423; TULP1; ZNF471; BRDT; GCM2; ZNF556; GRHL2; MEIS2; ZBTB17; HNF1A; TCF21; ZNF780B; DACH1; ZNF669; HEYL; ZXDC; KAT2B; PCGF3; ZNF407; PRDM13; CEBPE; SOX14; PRDM10; NOCT; RXRG; TCEA2; KDM5C; THAP3; FOXB1; ZSCAN18; REL; ZNF107; ATF6B; RAX; RARG; DOT1L; TAF4B; ZNF711; ZNF155; HSF4; ZSCAN9; DLX6; HOXC5; PBXIP1; MXI1; ZXDB; MED25; ZNF654; ZNF81; CRTC1; TBX21; AIRE; TGIF2; NKX6-1; ZNF440; POU3F4; CREBL2; ZNF214; THAP9; POU4F2; ZNF80; HOXA6; ZNF444; CUX2; ZNF674; GFI1; OVOL2; TUB; ASH1L; TCF4; NKX2-5; MLLT1; ST18; FOXE1; GLI1; HIC2; ZNF771; FOXL1; LMO1; TLX3; GCM1; PEX14; ETV3; ZNF174; FOXJ1; ZNF93; ZNF623; ID4; NR4A2; ATF7; CBFA2T2; ZNF175; SUPT3H; ZNF79; MYT1; ZNF343; FOXP3; VHL; ZNF74; NPAS1; SUMO1; EN2; ZNF134; ZNF157; ZNF329; HIVEP3; ZNF124; ARID4A; HOXA3; CBX7; HOXC11; ARRB1; MXD3; HLX; IRF6; ZNF480; ZNF426; BNC1; ONECUT2; ZNF768; SIX5; HOXD9; BACH1; HIC1; POU4F3; ZNF611; ZNF334; SNAPC4; ASCL2; DAXX; LHX6; ZNF324; ZFP69B; FOXI1; ARID5A; TAL1; ZNF552; GMEB1; DMRT1; ZNF668; TBX1; NR2E1; SMARCA1; ZNF222; HNF1B; MSX2; ACTL6B; MAFK; RSF1; MYEF2; CBL; ARL2BP; ZNF778; TAF1; ZNF234; JUP; RFXAP; VSX1; TFAP4; STAT4; HOXD13; SRCAP; PAX2; ZBTB39; ZBTB7C; DYRK1B; MEIS1; IKZF1; BCL11A; ZNF764; ZNF460; THAP7; GATA3; ZNF10; ZNF419; CIC; IKZF4; DLX2; ZFY; HOXB3; KLF1; SUPT5H; ZNF219; NR4A1; ZSCAN31; DLX5; KDM4C; ZNF710; NR4A3; UTF1; NR1H4; TTF2; CITED2; ZNF133; POU5F1B; BARX2; ZNF394; IFNB1; MYF5; ZNF292; GBX2; ZNF41; CBX4; ZNF813; MDM2; ZNF551; ETV7; NFKB2; ZNF34; RXRB; ERF; HOXB5; NFE2L3; NCOA2; NFE2L2; HAND2; ZNF112; MYNN; ZNF287; TBX10; SIN3B; TAF7L; TEAD3; SUV39H2; SIX3; SNAI1; SUPT7L; ZFP37; NR1H3; AEBP1; PIAS4; ZNF468; HMGXB3; ZNF44; FHL5; NHLH2; ZNF177; SUPT4H1; JAK2; TONSL; PITX3; ZEB1; PRRX1; NFAT5; ZNF83; YEATS4; FOXN2; KAT6B; HOXA2; ZNF205; YBX2; NR0B1; EPAS1; MXD4; ZKSCAN7; ZNF562; FOXC2; NFATC4; RORA; ELF2; MBD4; ZNF165; HOXC4; WDR77; SETDB1; TXNIP; ATN1; ARHGAP35; TFAP2A; BAZ2A; BACH2; ZNF131; ZSCAN16; FOXN3; E2F1; HOXD1; VAX2; ZNF589; APBB1; ZNF211; LDB1; ISL1; SIM1; ZBTB6; TCF7L2; MED14; NLK; HIPK2; PITX2; PKNOX2; SMARCD1; ZNF248; PAX6; INSM1; EVX1; FUBP1; FOSB; RERE; PAWR; ARNT; SOX11; TLE2; SKIL; IRF8; ZNF430; MEOX1; PEG3; TRIM24; RBL2; ZNF580; IRF1; BPTF; BCL6; PLAG1; ATF3; LYL1; FOXF1; CERS4; PHOX2A; EHMT2; OSR2; GATA6; PPARD; TGFB1; TOX4; NR1I2; POU3F2; KLF11; DBP; MYCN; LHX2; TAF11; PROX1; MLLT10; BHLHE41; ZHX2; CERS6; ARID3A; SPDEF; ZNF432; MECOM; GLI3; VDR; EMX2; FOS; ZNF226; ZIC1; ZNF354A; NANOG; VPS72; TBX3; NFIC; KLF7; E2F8; SP140; MYBL1; ELF4; TRPS1; FOXL2; HIPK1; CHD9; HEY2; HOXD11; FOXA2; CREM; TULP3; CNOT3; THAP10; SALL1; TRIB3; TCF7L1; HDAC4; SSX1; ZNF232; SP140L; GATA4; FOXF2; TCF7; ZBTB20; FOXA1; LEF1; PBX1; MNDA; OLIG2; SMAD6; HOXB2; ACTL6A; TOX; EN1; SMARCB1; NFATC3; TFAP2C; ZNF22; TOX3; ASCL1; FLI1; PBX3; ZNF512B; POU2AF1; NR2F1; PLAGL1; ARNT2; TRIM22; INSR; SNAI2; CRYM; SSBP2; CREB1; TBX2; FOXO4
Down-regulation 178 CCNA2; USP22; ADRB2; MYC; FOSL1; RBBP4; NUP62; FHL2; TCERG1; CRK; NFKBIA; EZH2; HDAC2; ATF6; HOXA5; UBE2I; TBL1X; RBM14; TBP; DNAJC2; AATF; SNW1; CENPF; CDK7; SMARCC1; HSBP1; HNRNPD; ATF4; ENO1; RAN; BCLAF1; NRIP1; NPM1; RBBP7; MLX; CENPB; SMAD3; NACA; TBPL1; HOXC6; YBX1; NCOA6; ITGB3BP; MBD2; CBFB; TRIP6; PA2G4; PMF1; TRIM28; PARP1; YWHAB; ADNP; SFPQ; BRD8; NONO; MED6; SMARCA2; TP53; PATZ1; BLM; NFIL3; XBP1; XRCC6; SMARCD2; CARM1; PHF20; BAZ1A; ZFP64; SMARCA5; NFE2L1; NFKB1; FOXJ3; TRIM16; NCOA4; DDX54; NELFB; ECD; BRCA1; NCOR2; PIR; ZBTB16; TRIM32; PTTG1; SMARCE1; MED1; SSRP1; HOXA10; RUVBL2; NR2F2; ORC2; PUF60; EDF1; FLNA; MAGED1; BIRC2; BRD3; SAP30; CCDC59; UBP1; JARID2; CTR9; ZNF146; HMGB3; PRKDC; VEZF1; CNOT1; ELF1; MNAT1; KAT7; BMI1; SF1; BAZ1B; C1QBP; CHD7; DDX5; KLF2; ELK3; AGO2; ENY2; COPS5; SIM2; AFF1; HMGB1; RBM39; ZBTB38; PRPF6; SOX9; HOXB7; CRY1; FOXO3; FOXM1; RNF6; TAF9; HMGB2; FOXD1; PPRC1; DNAJC1; TBL1XR1; BTF3; HOXC10; DEK; SUV39H1; TCF12; TTF1; DDX17; HDAC1; FOXO1; ABL1; SMAD2; TAF9B; MTDH; TRRAP; STAT6; TAF10; PURA; HES1; STAT3; BHLHE40; ING2; TOB1; IKBKAP; IRX5; NKX3-1; MED24; PCGF2; SCAND1; KLF9; PQBP1; ZBTB18; ETS2; APEX1; RBPMS; TSC22D1; CTBP2; BASP1; PITX1; STAT5B; TCFL5