Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16248 Linsitinib GSE70138 MCF10A Human 24h 10uM EID0005
Types Number Response transcription factors
Up-regulation 44 ZNF586; E2F2; TSC22D3; ZNF134; TCFL5; ZNF606; ZNF419; ZNF211; ZNF587; ZNF671; ZNF91; IRF7; ZNF264; ZNF304; ZSCAN18; ZNF551; ZNF544; ZNF329; ZNF135; ZNF44; ZNF665; ZNF83; ZNF611; ZNF415; HOXD3; ZNF217; WNT4; CDYL; ID3; TXNIP; E2F5; SMAD3; TBL1XR1; ZNF430; ZNF93; BTG1; IRX5; HMGB3; FOXO1; HOXD1; ZBTB16; ZBTB18; KLF10; ID1
Down-regulation 22 CREG1; EZH2; UBP1; TBL1X; SUB1; NR2F1; ELF5; NR1H3; SSX1; MECOM; STAT1; DLX2; BHLHE41; HEY1; NR4A2; DACH1; MNDA; MYRF; SPDEF; SATB1; MEIS2; FOS