Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16246 Ruxolitinib GSE70138 MCF10A Human 24h 0.12uM EID0005
Types Number Response transcription factors
Up-regulation 18 NR3C1; ID4; SETD3; ERG; WWTR1; IRF7; NFAT5; NKX3-1; NFIB; HOXB2; HOXC10; IRF8; SATB1; IRX5; MYBL1; KLF9; EGR3; SOX9
Down-regulation 20 AEBP1; ZNF516; ZMYND8; ESR1; IKZF1; MED1; SOX17; FOXG1; EMX2; LEF1; PIR; OSR2; TCF4; TBX3; TSC22D1; FOSL2; KLF4; TXNIP; CREB1; FOS