Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16242 Alpelisib GSE70138 MCF10A Human 24h 0.04uM EID0005
Types Number Response transcription factors
Up-regulation 58 KDM5A; TCFL5; NFATC3; ARID4A; WHSC1; WWC1; ID4; SIX1; RSF1; TCF20; JARID2; CHD7; TAF9B; BRD3; WWTR1; ARRB1; CREB3L2; CUX1; RBPJ; ING3; PEG3; NCOA1; PURA; SMARCA2; DACH1; TFCP2; ZBTB38; SERTAD2; SOX9; NR1D2; STAT5B; SATB1; MYB; CBX6; TAF10; ZBTB18; NR2F1; HDAC4; HIPK3; CITED2; IRX5; TRIP6; SPDEF; BHLHE40; MNDA; AFF1; MEIS1; BCL3; FOXC1; EDF1; TOX3; GATA6; TRPS1; LITAF; SOX11; ZIC1; MAFB; PBX3
Down-regulation 29 NFE2L1; ERF; LDB1; PEX14; TGFB1I1; COPS2; POU2AF1; C1QBP; ATN1; NR0B1; CTNNB1; RORA; HMBOX1; SOX13; ZFP36L2; NKX3-1; TCEA2; BACH2; FOXD1; IRF6; DLX5; ESR1; ZBTB16; PIR; FOXG1; VPS72; LEF1; ARNT2; MEIS2