Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16241 Alpelisib GSE70138 MCF10A Human 24h 0.12uM EID0005
Types Number Response transcription factors
Up-regulation 11 SMAD3; CARHSP1; ARNTL; RBPMS; ZBTB38; JUNB; AHR; PTRF; ELF3; HMGB3; ELK3
Down-regulation 19 TLE1; RXRA; ZEB1; BACH2; SOX11; HEY1; CREB1; JARID2; PAX5; BCL11B; HHEX; TRIM22; TLE4; LEF1; EGR2; TFAP2C; ARNT2; SATB1; WT1