Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16239 Alpelisib GSE70138 MCF10A Human 24h 1.11uM EID0005
Types Number Response transcription factors
Up-regulation 40 GLI2; HOXA10; RFX5; TCF21; ISL1; IRX4; ARID5B; AEBP1; SIX3; ARNTL2; KDM5D; NFATC1; FLNA; THAP11; IRF8; KLF5; TCF4; ZBTB16; KLF6; EHF; NR2F2; EYA1; BNC2; GATA6; MEOX2; TGFB1I1; FOXD1; PAX5; DLX5; KLF9; MYCN; PBX1; FOSB; TOX3; FOXF1; MAF; INSM1; SNAI2; HOXC6; ID1
Down-regulation 23 DDIT3; CHD7; ZNF43; ZNF200; VPS72; ZNF468; RBBP8; NR4A2; TOB1; RNF14; NR1D2; ACTL6A; TGIF1; SALL1; PIR; CITED2; ATF3; ZNF91; TRIB3; CREB1; BASP1; PEG3; SATB1