Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16238 Alpelisib GSE70138 MCF10A Human 24h 3.33uM EID0005
Types Number Response transcription factors
Up-regulation 46 ETV1; VGLL4; ZMYM2; PCGF3; HDAC9; PBXIP1; PNRC1; ZFP36L2; ETV4; IRX4; TXNIP; IFI16; NPAS2; REPIN1; XBP1; EHF; ING4; ZHX2; RERE; ID2; RUNX1; TRIM29; TP63; ELF5; TCF4; MYCL; FOSB; MAGED1; OLIG2; SOX11; TFAP2C; ARID4B; AEBP1; ARNT2; ZSCAN18; KLF4; JUP; BACH2; ZBTB16; CTBP2; TRIB3; NR4A2; MAFB; HMG20B; ID1; FOS
Down-regulation 22 ENO1; TMF1; CRY1; RBPJ; SMAD7; RORA; PAX6; ZBTB38; SMARCA1; ZEB2; STAT3; BHLHE40; ZNF423; IRF4; MYT1L; SAP30; DACH1; YWHAB; BASP1; PITX1; EMX2; SATB1