Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16237 Alpelisib GSE70138 MCF10A Human 24h 10uM EID0005
Types Number Response transcription factors
Up-regulation 78 TSC22D3; CALCOCO1; CEBPD; PNRC1; ZMIZ1; BCL6; HBP1; CREBL2; ING4; ZNF131; CDIP1; BTG1; SALL2; LIN28A; PBXIP1; HMGB3; ZNF665; TCEB2; TFEC; ARID5B; SOX11; PRDM2; ZNF83; ZNF117; FLI1; MYCL; CUX2; SOX3; PBX1; WNT4; ISL1; TCF7L1; ZIC3; IRF6; ZNF160; NFATC1; ERBB2; ZNF467; ZNF217; FOXN3; MXI1; NR5A2; GATA6; TRIM22; KLF11; NANOG; NR1H4; BASP1; EN1; HMGN3; ZNF232; TCF7L2; KLF4; ZNF512B; TAL1; TCF4; CITED2; ERBB4; MECOM; DACH1; ID1; INSR; ID3; ARNT2; ZNF91; AEBP1; NFE2L3; ASCL1; PBX3; MYBL1; SOX9; MAGED1; MYCN; ATF3; TXNIP; MNDA; NFATC4; MAFB
Down-regulation 38 FOSL1; CCNA2; EGR1; TBPL1; DNAJC1; TEAD1; NFYA; CTR9; TRIM28; HSF2; CRY1; C1QBP; CCDC59; MSX1; SFMBT1; SFPQ; CHD1; SLC2A4RG; ECD; EGR3; CCNE1; HOXB7; ETS1; MED1; LEF1; RBM14; STAT3; BMI1; NR2F2; BCLAF1; YWHAB; HOXC6; CALR; NR1D2; PIR; HOXC10; SATB2; STAT5B