Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16235 Nvp-bez235 GSE70138 MCF10A Human 24h 0.12uM EID0005
Types Number Response transcription factors
Up-regulation 157 TSC22D3; CALCOCO1; PNRC1; SOX4; HMGA2; FHL2; HBP1; EZH1; BAZ2A; CREBL2; MED12; HDAC5; NFKBIA; TSG101; ZNF264; KDM4C; NR2C1; KLF6; PBXIP1; ZMIZ1; BTG1; SRCAP; CDK7; E4F1; UBE2B; MAFF; SCMH1; ZMYM2; MED23; HIVEP1; STAT2; NR1I2; NKX2-1; NFATC1; ARID4A; ZSCAN18; CIR1; MXD4; MNT; RBPMS; RELA; ZBED2; CUX1; CDIP1; SETDB1; RUNX1; ZNF83; NCOA2; ZHX2; ZNF205; ZBTB43; HINFP; AES; MEOX2; ZNF175; MYBL2; HDAC9; COPS2; FOXN3; SMARCA2; YEATS2; ZNF688; NAB2; ZNF91; TGFB1I1; ZNF160; PRMT2; STAT6; ZNF430; ATF7IP; CBFA2T3; JUP; HLX; ERBB2; HOXA3; FOSB; BASP1; HIVEP2; MED13; IRF9; ZBTB38; ZNF606; ZNF136; TFCP2L1; PFDN5; ZNF611; TCEB2; ZBTB20; ZNF500; HTATIP2; IRF7; YBX1; SKI; GTF2F1; SP110; TERF1; ARNTL; ZNF358; ZMYND8; ELF3; MEF2D; ZBED1; JAK2; PRDM2; CERS6; INSR; TLE2; PDLIM1; NRIP1; SALL2; ST18; INSM1; TGIF1; FOXO3; TFEC; KAT2B; TFDP2; CSDE1; BCL11A; NR1D2; CREB3L2; RBPJ; TSC22D2; ZNF117; KLF7; TXNIP; ZNF217; KLF2; LMCD1; ATF3; HMBOX1; PLAGL1; TAL1; ZNF652; TULP3; TRIP6; CITED2; KLF10; ELF5; SAP18; BCL3; ZNF512B; KLF9; FOXD1; KDM5B; TCF4; MAF; IRF6; RELB; TRIM22; SOX11; NR4A2; KLF4; KDM5D; PEG3; CREB1; FOXO4
Down-regulation 97 CCNA2; TFDP1; MYCBP; EZH2; DNMT1; PARP1; CDK2; PSMC3IP; GMNN; ZNF473; WDR77; RUVBL1; FOSL1; GTF2I; BRCA1; GTF2A2; TAF1A; SNIP1; TCERG1; RBL1; FOXM1; CENPF; RBBP8; RBBP7; YEATS4; HSF2; HMGB2; WDHD1; ZNF672; C1QBP; TAF5; SUB1; ETV1; ZNF614; KMT5A; BRD7; PMS1; ABT1; MSX1; TFAM; PLAGL2; TAF9B; MED20; FUBP1; UBP1; CBFB; MTF2; NR2F1; XRCC6; PA2G4; PPRC1; BLM; SHOX2; ISL1; MECOM; RBBP4; RAN; ZNF200; TRIM28; LEF1; SAP30; PRKDC; PREB; BRIP1; RBM14; ILF2; RNF138; SSX1; TEAD4; HOXA11; GATAD2A; CEBPG; PITX1; MYBL1; ID2; FLNA; MED24; FOXL2; CALR; YWHAB; HLTF; NKX3-1; PTTG1; STAT1; OSR2; NR2F2; FOXF2; SUV39H1; HOXB6; PIR; DLX2; PBX3; MEIS2; IKBKAP; WT1; HOXC6; ID1