Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16234 Nvp-bez235 GSE70138 MCF10A Human 24h 0.37uM EID0005
Types Number Response transcription factors
Up-regulation 132 TSC22D3; GATA3; SOX4; HBP1; HMGA2; FHL2; ZNF33B; PHF20; CREBL2; CALCOCO1; PBXIP1; HDAC5; HDAC6; CDK7; ATF4; TSG101; ZNF160; THAP11; BPTF; ELF4; DLX4; MNT; ZNF688; MED12; ZNF768; ZNF358; HIVEP1; MAFF; ZNF665; ATF2; GBX2; ZNF611; RBBP5; SP100; SPI1; HIVEP2; ZNF536; IRX4; ZMYM2; PNRC1; ZNF573; ING4; BTF3; CIR1; ZNF140; ZNF83; ZNF532; ZNF292; HOXB13; NFATC1; SRCAP; ZKSCAN1; NCOR2; ZFHX3; ZBED1; PFDN5; BCL10; MXI1; FEZF2; EGR1; REL; E2F5; TBX1; KDM5B; CHD9; SMARCD3; NRIP1; FOSB; ZNF623; NCOA4; SOX9; ZFP36L2; ERBB2; GTF2F1; RUNX1; NCOA2; DDX5; TCF7; ID2; REPIN1; ZNF354A; TGFB1I1; TRIM16; PCGF2; TCEB2; FOXC1; HMGA1; AES; ZNF165; KLF4; INSR; STAT6; TBX3; TAL1; ZNF117; NR1H3; TXNIP; ZNF32; PDLIM1; FOXJ3; ZNF415; IRF7; INSM1; IRF6; BTG1; MEOX2; GTF2IRD1; NRBF2; SMAD6; ELF3; MAF; SMAD7; RBPMS; TLE1; TSC22D1; ZNF91; EN1; LITAF; ATF3; BCL11A; KLF2; HOXD1; TGFB1; TFAP2C; VPS72; ZSCAN18; NFE2L3; TRIM29; BASP1; ARNT2; ASCL1; FOS
Down-regulation 87 CCNA2; TFDP1; MYCBP; MYBL2; EZH2; DNMT1; CDK2; RUVBL1; PARP1; FOSL1; GTF2A2; GMNN; BRCA1; PA2G4; DR1; PSMC3IP; FOXM1; C1QBP; TP53; RUVBL2; TFAM; PTTG1; WDR77; SAFB2; ZNF692; NUP62; ITGB3BP; CHAF1B; SMAD5; EED; HMGB1; ABT1; HMGB2; MTF2; TAF5; PMS1; CBX5; RBM14; NFIL3; HLTF; GABPA; SUB1; ZBTB24; TRIM28; SSRP1; CENPF; BLM; SFPQ; RNF138; TCF21; RFX5; RBBP8; HIRA; PRKDC; HOXA11; PAX6; HMG20B; GATAD2A; ENO1; RBBP7; POLR2A; HOXB2; SAP30; STAT1; KLF9; IRF4; POU4F1; NR2F1; ZBED2; HNRNPD; SUV39H1; HOXB7; MED1; PEG3; SALL1; ZBTB18; ZEB2; PURA; IRF1; HOXC10; HOXB6; ID3; CREB1; EGR2; WT1; PBX1; SATB1