Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16233 Nvp-bez235 GSE70138 MCF10A Human 24h 1.11uM EID0005
Types Number Response transcription factors
Up-regulation 482 CALCOCO1; ARID5B; HBP1; ZNF268; ZNF350; TSC22D3; ZNF586; PNRC1; RFX3; ZNF671; NR1H2; ZNF33B; SCAI; POU6F1; SOX18; ZNF91; ZFP2; NEUROG3; BARX1; CBX2; ZNF669; RFX1; PRDM14; RING1; TCF3; ZNF117; HINFP; GFI1B; ZBTB3; SP4; EZH1; PRDM9; ZNF304; POU6F2; NAB2; ZNF701; EP300; CAMTA2; ZNF768; ZNF141; CIR1; GLI2; PAX4; ZNF225; ZNF500; FEZF2; ZNF254; ING4; ZNF665; BRWD1; NR5A1; IRF9; HLX; ZNF549; ZNF79; TBX5; ZNF682; ZBTB44; GRIP1; CHD2; PHIP; CREBL2; SSBP3; HNF4G; ZNF442; TSHZ2; ZIC4; GCM2; ZNF695; POU1F1; ZNF214; ASCL2; ZNF81; ZNF154; HDAC5; ZNF675; ZXDB; LHX3; ZNF155; TBX6; ZKSCAN8; ZNF688; ZSCAN2; JUND; E4F1; TLX2; ZNF814; ZIC3; ZNF257; ZNF674; GSC2; NEUROG2; ZNF80; ZNF112; TBR1; GBX2; ZNF177; THRB; ZNF75D; AFF2; ZNF780B; ZNF471; BACH1; ZNF157; ZNF749; ZNF550; ZNF135; ZNF43; ZNF667; ZNF623; ZNF440; ASCL3; VHL; ZNF613; ZNF223; CBX7; ST18; ZNF573; SCRT1; TBX1; PRDM2; ZNF358; SRCAP; SPI1; SOX3; ZNF510; SUPT7L; ZNF492; SHOX; ZSCAN9; GRHL2; HOXD12; CBFA2T3; ZNF250; FOXD3; CDIP1; ZNF345; WNT4; ZNF419; SNAPC4; ZNF391; KLF8; POU2F3; ZNF606; CIZ1; SRY; ZNF407; EMX1; PBXIP1; TBX4; ZNF329; MAML3; HIC1; FOXN1; KLF7; MED12; ZNF93; DLX4; FOXE3; SOX14; SUPT4H1; TXNIP; ZNF132; THAP9; LBX1; PPP1R13L; ZNF460; ZNF85; NR1I3; ZNF180; ZFP69B; TCEA2; ZNF835; SOX1; FOXI1; TCF7L2; ZNF174; E2F2; ZNF41; FOXB1; JAK2; CRX; ZNF234; SOX4; SSX7; DOT1L; IKZF3; NEUROD1; FOXH1; ZNF611; TRPS1; TFAP2A; ETV2; GCM1; MSX2; PIAS4; ZNF136; VENTX; NEUROG1; ETV3; ZNF208; LZTR1; ZNF423; CDX4; ZNF507; ZKSCAN4; ZNF362; ATOH1; L3MBTL1; PEX14; KAT2B; TEAD3; TLX3; TCF7L1; ELF4; ALX3; LIN28A; HOXD1; TWIST1; ZNF253; ZNF235; CDK9; PCGF3; NEUROD2; NKX2-1; ZNF571; SOX21; SIX5; TAF1C; PRDM1; SUPT6H; OSR2; NHLH1; ERBB4; NKX3-2; ZNF217; PRDM10; DCC; HOXB8; NEUROD4; ZSCAN32; ZNF506; MLLT1; HOXB1; TAF6L; TFEC; BRDT; ZBED1; CBX4; ZNF711; ZNF133; WWP1; SOX17; ZNF134; ZNF287; DLX5; ZNF415; ZNF816; MAPK8IP1; HESX1; TEF; PRDM12; AIRE; TP73; ZNF334; GON4L; ZNF778; RXRG; CUX2; MYEF2; ZNF557; AES; ZNF493; ZNF34; TULP1; POU4F3; ZNF219; CBFA2T2; ZNF264; STAT2; MEOX2; ZNF529; LHX1; NCOA2; NPAS1; HSF4; SKIL; ZNF770; ZHX2; MAF; KLF13; SOX13; UBE2B; SETDB1; PROP1; PHF1; CSDC2; VAX2; CDX1; DYRK1B; PPARD; ZNF354A; ZBTB17; ZFPM2; ZNF14; FOXN3; SIM1; NR4A3; RORC; ZNF222; DMRT1; ONECUT1; BNC1; REL; SALL2; ZNF74; TFEB; MXD4; EPAS1; LHX2; NFKB2; SUPT3H; DLX2; HSF1; ZEB1; THAP7; TERF1; RARG; CERS4; CARF; KDM5C; KLF11; ZFY; ZNF195; HOXB13; TFDP2; ZSCAN16; MYF5; STAT4; PLAG1; MEOX1; NFE2L3; HOXD13; ZNF140; NR5A2; INSR; KLF3; TCF4; EVX1; MEIS2; ARL2BP; NPAS2; ZSCAN18; SOHLH2; SOX5; BCL11A; PAX6; ZSCAN31; ZNF205; HMGA1; HMBOX1; RBPJ; MEF2C; ZNF654; ARID3A; IRF6; TLE2; TGFB1I1; ZFHX3; VDR; DAXX; SIX3; TBX3; MEF2D; ID4; ZNF232; LMCD1; SOX2; BAZ2B; PAWR; ZBTB16; NFIC; TRIB3; BACH2; HOXD3; NHLH2; POU2F2; SKI; MYRF; MNT; ZNF10; LDB1; ZFHX4; TCEB2; FOXE1; SOX11; PRRX1; ZNF426; TLE4; MBD4; EHMT2; BHLHE41; SMAD3; HEY1; CAMTA1; NR1I2; AEBP1; NR0B2; JUP; OLIG2; HIPK2; ZNF165; SMARCC2; TFAP2C; TCF21; LOXL2; HLF; ARID1A; HMX1; ZNF160; ATF7IP; ZNF467; FOXF2; BNC2; ZKSCAN7; ACTL6B; RBPMS; ZNF189; FOXF1; ZNF331; HEY2; ID3; GATA6; ARNT2; SALL1; ZNF281; HHEX; POU2AF1; NFATC4; SMAD6; HOXB5; IKZF1; INSM1; HDAC9; ZNF589; IRF8; EN1; TULP3; ZFP36L1; NR1H4; MYCL; ERBB2; ELF3; TGFB1; VPS72; TRIM29; NANOG; HIPK1; MYCN; TAL1; NFATC3; SNAI2; MXI1; HIC2; FOXG1; SOX10; PBX3; ZNF512B; STAT5B; FLI1; MYBL1; SOX9; PLAGL1; LITAF; PBX1; TSC22D1; KLF4; CRYM; MEIS1; ATF3; SSBP2; ID1
Down-regulation 112 CCNA2; MYCBP; PARP1; ADRB2; TFDP1; FOSL1; EZH2; CTR9; NUP62; GTF2A2; HDAC2; TCERG1; RBBP4; HLTF; GMNN; DNAJC2; TBP; DEK; RBBP7; RUVBL2; ETS1; BAZ1A; EED; TFAM; CBX5; BRD2; BMI1; CCNC; DRAP1; ITGB3BP; HOXA5; PTTG1; MAGED1; RNF6; BAZ1B; BCLAF1; SUB1; SMAD5; SSRP1; RBM14; PA2G4; SMARCA2; HSBP1; ELF1; MED1; HOXC6; SFPQ; IRX5; RNF4; ASH2L; HMGB2; XBP1; RAN; ZNF146; WWTR1; NR2F2; MYBL2; PBRM1; C1QBP; WHSC1; BRCA1; RBBP8; BASP1; KDM2A; SREBF1; UBP1; TRIM28; HMGB1; PRKDC; TRIP6; CENPF; PMS1; ATF5; TRRAP; HSF2; ING3; HMGB3; HOXC10; PSIP1; HNRNPD; GATAD2A; RNF138; AFF1; BLM; JARID2; HDAC1; TRIM32; PIR; ENO1; PURA; ZBTB38; SUV39H1; HIPK3; CBFB; CBX6; NR1D2; BRD8; ZBTB1; NKX3-1; CALR; HES1; SAP30; FOXJ3; FLNA; ELK3; TOB1; HOXB7; PITX1; ASCL1; TCFL5; IKBKAP; LEF1