Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16232 Nvp-bez235 GSE70138 MCF10A Human 24h 3.33uM EID0005
Types Number Response transcription factors
Up-regulation 289 CALCOCO1; TSC22D3; ADRB2; HBP1; EZH1; PPARD; ZNF665; ZNF611; ZNF586; SOX4; IRF9; EP300; ZNF304; ZBTB43; SP100; ZFHX3; NCOA3; PHIP; ZNF768; ZNF264; ZNF33B; ZNF160; ZNF217; RING1; ATN1; KLF13; ZNF580; REL; ZNF91; SSBP3; TGFB1; NAB2; SOX12; TSHZ2; LMX1B; ZSCAN18; ZFHX2; ZNF358; IRF6; MZF1; HMGA2; HDAC5; MECP2; ZSCAN9; ZNF667; NR1H2; SPI1; ZNF688; CIR1; HDAC6; WNT4; ZNF671; ELF4; PNRC1; ZNF606; SALL2; ZNF44; ATF2; ZNF134; SUPT6H; TP63; TCF3; TGFB1I1; RFX2; ZNF211; THRB; ZBTB7A; PCGF3; PPP1R13L; RORC; NHLH1; TCEA2; LHX3; ZNF175; SRCAP; YEATS2; TUB; ZNF652; KLF1; MED12; CARF; ZKSCAN4; ZNF43; ZNF235; ARID1A; ZNF669; ZNF532; ARID5B; PRDM14; BCL10; ZKSCAN8; ZNF135; TAF1C; HDAC9; CDIP1; SUPT3H; JUND; L3MBTL1; ZNF778; EYA1; CRTC1; JAK2; BACH1; SUMO1; ZNF224; AFF2; TEAD3; FOXJ2; BPTF; CHD9; NFE2; TRPS1; ZNF154; FLNA; PRDM12; MED16; RFXANK; HOXB13; HOXA3; TCF7L2; CDK9; ZNF467; STAT2; KLF6; CBX4; ZNF350; AES; MNT; ZMYND8; ZNF112; RCOR3; NEUROG1; GFI1B; HIVEP1; TFE3; PHOX2A; ARID5A; HOXB1; TFAP2A; SOX13; KAT2B; ARID3B; BCL3; ZNF223; KLF15; ZNF93; SIRT2; ZNF426; SPIB; EVX1; MYCL; ZNF354A; ERF; GRHL2; CBX7; PCGF2; HLX; ZNF117; SNAI2; BTG1; ING4; IRF5; ZNF629; HOXD1; HOXA4; LIN28A; PHF1; NFKB2; ZNF362; ZNF444; TULP3; ZNF423; MYT1; ZBED4; PROP1; ZKSCAN1; ZNF544; NFATC1; AHR; CIZ1; ZNF329; RARG; RARA; EHF; NKX2-1; MED13; CEBPE; TCF25; PKNOX2; ZBTB20; SP3; ZNF75D; POU2F2; PBXIP1; ZNF587; IRF7; ZIC3; PEX14; OSR2; ZNF83; ZNF430; MAZ; CNOT3; MED15; THAP11; ZFP36L1; SIX6; MXI1; ZFHX4; SIX3; FOXN3; ERBB2; MAF; ZNF500; SERTAD2; PDLIM1; TCF7L1; BNC1; HMBOX1; BRWD1; PRRX1; IKZF1; MAFF; CBFA2T3; HMGA1; DLX5; CDYL; FOXA2; ZNF415; BAZ2B; AEBP1; CERS4; CITED2; CUX2; BCL11A; KLF7; CSDE1; SOX17; CREBL2; TCEB2; JUP; NCOA2; VDR; BRD4; SMARCC2; ZNF12; SOX2; TBL1XR1; ERBB4; TAL1; KLF11; TFEC; GATA6; ESR1; RXRA; FOXF2; BCL6; FOXF1; FOXO3; IRF8; CTBP2; ZNF512B; SOX10; NFATC4; KLF9; TRIB3; ARNT2; ZBED2; NCOR2; HEY1; KLF4; SOX9; ZFPM2; TFAP2C; VPS72; TRIM29; ZNF589; RELB; ARID4B; TXNIP; CREB1; NFATC3; TGIF1; TSC22D1; ZIC1; ATF3; EMX2; FOS; MAFB
Down-regulation 104 CCNA2; MYCBP; EZH2; PARP1; TFDP1; RUVBL1; GTF2A2; MYBL2; FOSL1; TFAM; GMNN; ZNF672; TBP; NFIL3; C1QBP; ITGB3BP; HDAC2; RBBP4; BRCA1; HLTF; EED; PSMC3IP; TRIM28; RUVBL2; PA2G4; CRY1; BAZ1A; SUB1; CREBZF; BMI1; CBFB; TCERG1; CHAF1B; RBL1; RNF6; RBM14; SSRP1; POU4F1; FOXM1; SMAD1; ELF1; SMARCA5; HSF2; RBBP7; EGR4; MTF2; MSX1; PREB; BCLAF1; TSC22D2; PURA; RAN; SREBF1; TAF1D; GABPB1; ENY2; CTR9; UBE2L3; HOXA1; HMGB1; TAF9; UBP1; DNMT3B; XBP1; RNF138; SFPQ; BCL11B; MTDH; CCDC59; PTTG1; PRKDC; PPRC1; ID2; ECD; ING3; RB1; HES1; PSIP1; LEF1; IKBKAP; HNRNPD; PUF60; HOXC6; FOXO1; CHD7; TRIM32; GATA4; ING2; NPM1; CENPF; NFIB; BASP1; CEBPG; PEG3; SAP30; SUV39H1; ZBTB18; STAT1; HOXB7; RBPMS; WT1; POU2AF1; PPARG; PBX1