Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16231 Nvp-bez235 GSE70138 MCF10A Human 24h 10uM EID0005
Types Number Response transcription factors
Up-regulation 266 ZNF586; TSC22D3; HBP1; ZNF91; ZNF688; CALCOCO1; PNRC1; ZNF304; PBXIP1; ARID5B; ZNF134; EZH1; ZNF419; ATF4; ZNF671; EP300; CREBL2; ZNF268; SRCAP; FHL2; MZF1; ZNF611; DAXX; TBX6; LIN28A; ZNF264; LMX1B; ZNF33B; TGFB1I1; ZNF211; HDAC5; MED12; AES; RING1; CBX7; SOX4; ZMYND8; ZNF337; ZNF606; ZFHX2; E4F1; DLX4; STAT2; ZNF43; ZNF350; ZNF224; BACH1; NEUROD6; TLE2; ZNF551; ZNF500; CBFA2T2; ZNF112; TBX10; NAB2; ZNF665; HINFP; ZNF701; CIR1; ELF4; THRB; HMGA1; ZSCAN18; ZNF154; ZNF235; AFF2; CBX4; ZNF510; SSBP3; KLF6; REL; TSHZ2; ZNF93; CBFA2T3; ZIC3; MKL1; GRHL2; KLF3; TBX4; RFX2; ZNF155; ZNF536; ATOH1; MNT; DLX6; IRF6; ZNF426; LMO1; LHX3; E2F2; PRDM12; JAK2; BTG1; GBX2; ZNF117; ARID1A; CDIP1; FOXJ2; SETDB1; ZKSCAN4; IRF7; HDAC9; ZBTB7B; SPI1; IRF9; NFIX; LITAF; YEATS2; ZNF83; HEY1; ING4; FOXN3; ZNF587; ZNF345; SUPT3H; BCL10; IRF5; ZNF667; ZNF532; ZBED1; ZNF223; ZNF354A; ZNF358; TCF7L2; ARID3B; HIF3A; PPP1R13L; WNT4; NFATC1; POU5F1B; GATA3; LHX6; BRWD1; LMCD1; TCF7; ZNF544; ZNF160; FOXI1; ZHX2; IRX4; ZNF219; ATN1; FEZF2; ZNF85; HOXB1; ZNF136; BTF3; ZNF44; PHF1; RORC; SOX2; HMBOX1; TULP1; ZNF32; SCAI; TEAD3; TXNIP; PROP1; MAFF; CERS4; PHF20; ARID3A; TCF25; MED15; HHEX; ZBTB7A; PEX14; ZNF195; ZBTB16; TCEB2; ZNF415; TBX1; ERBB2; ZNF430; ZNF217; MEOX2; YAP1; MAF; LYL1; CARHSP1; SOX17; ZNF573; TFAP2A; NFE2L3; PRRX1; POU2F2; HIC2; TP73; KLF7; ID3; ZNF623; MEF2C; RARG; TAL1; ZNF239; SOX3; ZFPM2; SNAI2; GATA6; SIM1; MEOX1; JUP; CUX1; ST18; EHF; KLF11; MXI1; TFAP2C; PSPC1; VPS72; TRIB3; KDM5B; ID1; TCEA1; SALL2; FOXF1; THAP11; INSR; STAT6; TULP3; SCAND1; MYCL; ZNF652; ZFP36L2; KAT2B; KLF13; OSR2; TCEA2; AEBP1; ZKSCAN1; BHLHE41; IKZF1; ARNT2; TBX3; NR1H3; MITF; ZNF711; HOXD1; ZNF423; TGFB1; FLI1; FOXF2; NANOG; NKX2-1; DLX5; PBX1; SMAD6; ELF3; EN1; ZBTB20; IFI16; TWIST1; MEIS2; FLNA; ERBB4; HOXB2; MECOM; TOX3; ATF3; BCL11A; RELB; MYRF; NFATC4; TSC22D1; INSM1; FOS
Down-regulation 89 CCNA2; EZH2; TFDP1; MYCBP; PARP1; NUP62; TFAM; GTF2A2; DNAJC2; EED; NFIL3; TBP; TCERG1; CBX5; FOSL1; RUVBL1; HLTF; PA2G4; MYBL2; ADRB2; BAZ1B; PMS1; SIX1; ITGB3BP; ORC2; PHF8; HMGB1; SMAD5; CTR9; RUVBL2; ETV1; SUB1; SFPQ; WHSC1; TBPL1; PSMC3IP; BCLAF1; WDHD1; UBP1; TAF5; SAFB2; HSF2; RAN; DEK; BAZ1A; RBBP7; RBM14; ATF5; ING3; TP53; RBBP4; HMGB2; ZBTB24; ENO1; GATAD2A; PTTG1; CCNC; CCDC59; C1QBP; TRRAP; TRIP6; KDM2A; RBBP8; CENPF; BMI1; BLM; BBX; SAP30; CBFB; POLR2A; SUV39H1; HNRNPD; ID2; IRX5; MAGED1; ETV5; NR2F2; NR2F1; HOXC10; ZNF22; HMGB3; PURA; DACH1; NR4A2; MYB; LEF1; ZBTB18; CREB1; WT1