Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16216 Pd-184352 GSE70138 MCF10A Human 24h 1.11uM EID0005
Types Number Response transcription factors
Up-regulation 299 TSC22D3; PNRC1; CALCOCO1; ZNF268; EP300; ARID5B; TXNIP; BTG1; RFX5; CEBPD; IRF9; SOX4; ZNF33B; ZNF274; HSF1; GATA6; ZNF529; NCOA3; VGLL1; TCF21; DYRK1B; SIRT2; HBP1; DAXX; BARX1; MKL1; ZNF140; ATF4; SPI1; ZNF667; NR5A2; E2F2; JUP; PLAGL1; PBXIP1; SOX3; ZNF536; MZF1; ZNF606; CBX7; HIF3A; ZNF223; ASCL3; ID2; ZNF573; TULP2; RORA; ZSCAN18; IFNB1; ZNF14; CDIP1; ELF4; SMARCD3; CBFA2T2; PITX2; ZNF586; KLF13; NKX2-5; ZNF257; WNT4; CIC; NR5A1; LHX3; CSDC2; KLF5; ING4; BRD2; ZNF135; MYF5; NFIX; SOX2; PRDM1; ID3; ESR2; ZNF248; PRDM2; ZNF250; HNF4G; ZNF665; OSR2; ATOH1; NHLH1; TRIM29; PKNOX2; MEF2C; MYRF; ZNF131; SOX12; ZNF91; ZKSCAN8; CRX; TSHZ2; BRWD1; VENTX; PEG3; FEZF2; ZNF165; AFF2; MXI1; LZTR1; MECP2; MAF; NKX3-2; ZHX2; BNC2; KAT2A; JAK2; SOX21; ISL1; HIC1; PKNOX1; ZNF112; ZNF423; L3MBTL1; ZNF239; HINFP; ZNF571; EMX1; PRDM10; ZBTB3; KLF11; EZH1; ZNF117; ZNF93; MLLT1; ZNF362; HCFC2; GCM1; ZNF225; SRCAP; EED; CDX1; HDAC5; ZNF215; IKZF1; TBX1; HSF4; ZNF43; TEAD3; TLE2; NEUROG1; MAML3; CDX2; SOHLH2; RORC; EPAS1; TRPS1; TULP1; ZNF195; NPAS1; BRD4; ZNF74; ZNF136; GATA2; HESX1; ZNF44; THRA; ZNF350; MEF2D; ZNF345; CIR1; NEUROD1; BACH1; ZIC1; GLI3; NFKB2; RELB; ZNF34; RARG; TCF25; BCL11A; SIM1; HOXB1; CDK9; NR1H4; ZFP36L2; ZNF10; TLE4; IRF6; PROP1; KDM5C; ZNF467; ZNF85; FOXO1; MXD3; ZBTB17; CBFA2T3; ZBTB44; ZNF75D; TULP4; HOXA4; HLX; MEIS2; ZNF224; KLF3; FOXL2; ZNF682; SOX18; MDM2; TFEC; PRDM12; CITED2; POU2AF1; RBFOX2; NR4A3; REL; NR0B2; MNT; TRIM22; KAT2B; HMBOX1; ZBTB16; ZFPM2; EN1; DLX5; LDB1; TP73; SMAD6; FOXN3; HIC2; FOXO3; SSBP3; ATF3; IRF1; ZNF500; INSM1; TFAP2A; ZNF711; ZNF623; FOXF1; SMARCC2; NFATC1; NCOA2; HEY2; FOSL2; FOXJ1; ZNF331; TP63; ZNF141; TBX3; TOX3; ARL2BP; MYCN; BACH2; HOXD11; SP140L; ZNF415; ID1; GLI2; NHLH2; TCF7L1; CUX1; BCL6; ERBB2; BCL3; HOXA11; TAL1; DLX2; SHOX2; ZNF124; KLF4; PDLIM1; SOX17; PBX1; SNAI2; ELF1; STAT4; KAT6B; ST18; TCEA2; BBX; IRF8; SMARCB1; MEIS1; TULP3; FOXC1; PAWR; ZBED2; FOXF2; MYCL; TOX; NFATC4; DACH1; ELF5; ARNT2; MECOM; ERBB4; HOXD1; TCF4; TGFB1; SSBP2; HOXB2; ASCL1; KLF9; NFATC3; PBX3; FOS; MNDA; WT1
Down-regulation 100 FOSL1; CCNA2; EGR1; PSMC3IP; EZH2; NUP62; MTF2; CTR9; DNAJC2; NRIP1; MYC; NR2F6; CHD1; RHOA; MLX; FHL2; CENPF; DRAP1; ORC2; TCERG1; FOXM1; BRCA1; TRIP6; HMGA1; ETV1; BAZ1B; ETV5; BAZ1A; ATF1; DEK; ETV4; NKX3-1; BMI1; RBBP8; POLR3F; RUVBL2; CBFB; MYBL2; C1QBP; C1D; GMNN; NEDD8; TAF9B; EGR3; ITGB3BP; ETS1; SIAH2; SSRP1; SIX1; BCLAF1; UBE2I; HOXB7; BRD8; TBL1XR1; ENO1; RNF138; NPM1; JARID2; RBM14; CCDC59; SMAD3; BLM; BRD3; RRN3; HLTF; RREB1; CRY1; BHLHE40; HMGB2; ELK3; TRRAP; SERTAD2; NCOA6; ZBTB18; ING3; CTNNB1; PTTG1; ZBTB38; MSX1; YWHAB; AFF1; DNMT3B; CEBPZ; BATF3; EGR2; SUB1; MYB; NR2F2; PURA; MED1; SAP30; SUV39H1; PITX1; CITED1; HES1; STAT5B; IRX5; TSC22D1; LOXL2; TCFL5