Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16196 Pf-477736 GSE70138 MCF10A Human 24h 0.04uM EID0005
Types Number Response transcription factors
Up-regulation 47 PRDM1; SOX18; ARID5B; ELF4; ZNF75D; HBP1; HHEX; ZFP36L1; GLI2; SHOX2; NR0B2; BNC1; SOHLH2; CREB3L2; ZNF165; NR1H4; TRIB3; TRIM29; ZNF512B; SOX2; ZNF711; SSX1; KAT2B; SP140L; TFAP2C; HEY2; CUX2; ZBTB20; AEBP1; SALL1; DLX5; ARNT2; MECOM; BACH2; IRF6; MYRF; VPS72; HOXD1; TBX3; KLF11; ERBB4; TLE4; MNDA; NFATC4; MEIS2; ID1; MAFB
Down-regulation 24 TP53; ZBTB38; SIX1; BMI1; SMAD1; EGR3; BCLAF1; ETS1; RBPMS; CENPF; ZNF281; STAT3; DNMT3B; RNF14; MED1; IRX5; TOX3; SATB2; KLF10; ZBTB18; MYB; TSC22D1; STAT5B; CREB1