Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16193 Pf-477736 GSE70138 MCF10A Human 24h 1.11uM EID0005
Types Number Response transcription factors
Up-regulation 89 TSC22D3; KLF1; PNRC1; NR1H2; HBP1; ARID5B; ZNF33B; CDIP1; KLF15; WNT4; GATA1; TSG101; ZNF467; TRPS1; NFE2; HOXB13; NAB2; SOX3; BCOR; GFI1B; AR; VENTX; ZNF580; IRX4; ZNF667; NFIX; CDK9; PRDM12; HOXB1; TP73; ZNF219; ZNF611; CUX2; FOXA1; HLF; WWC1; EGR1; RARA; CREBL2; RARG; LYL1; TFAP2A; AEBP1; CERS4; TWIST1; ZMYND8; NR1H4; NR4A1; ZNF331; SOX2; STAT4; EGR3; SMAD3; BNC2; JUP; IRF9; RYBP; ID4; TFAP2C; ZHX2; RORA; SOX10; ZNF117; KAT2B; XBP1; TCEA1; ZSCAN31; BACH2; EYA1; TRIB3; CBFA2T3; ZNF91; TSC22D1; SIX2; NR4A2; SOX17; GATA6; ZBTB20; HOXB2; TRIM22; ARNT2; FOSB; TGIF1; FOS; MYRF; BCL11A; ATF3; EGR2; MEIS2
Down-regulation 42 CCNA2; ADRB2; TFDP1; HSF2; MYC; NUP62; EED; CRY1; EZH2; BMI1; PDLIM1; WHSC1; CHD7; SMARCA2; MNAT1; BRCA1; SAP30; RBM14; BCLAF1; SMAD7; CREB3L1; ZNF443; ING2; BATF3; TRIP6; ZBTB38; HOXB7; RBPMS; CALR; IRX5; HMGN3; ELK3; ZIC1; ZNF22; NR2F2; ZBTB18; BASP1; STAT5B; SUV39H1; HOXC6; SATB1; TCFL5