Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16192 Pf-477736 GSE70138 MCF10A Human 24h 3.33uM EID0005
Types Number Response transcription factors
Up-regulation 69 TSC22D3; BACH1; CALCOCO1; EGR1; PNRC1; TRIM22; HBP1; NR1H2; FOXJ3; IRF9; ATF4; SMARCD3; SUPT4H1; SKIL; SALL2; TCEB2; KLF3; BCL6; NRBF2; TAF7; CBX4; RORA; IRF7; FOSL2; ZNF467; EGR3; DDX5; CITED2; ZNF281; NKX3-1; HTATIP2; KAT2B; EDF1; KAT6B; CEBPG; MEIS1; TSC22D1; RYBP; BTG1; KLF9; TGIF1; ERBB4; KLF2; ZNF423; ZEB2; LMCD1; TRPS1; TLE4; PLAGL1; TAL1; FLI1; TRIM29; NR4A2; AHR; STAT1; NR1D2; MYCN; TRIB3; HLF; FOS; BASP1; JUP; TGFB1; EGR2; PITX1; KLF4; MAF; ID1; MAFB
Down-regulation 38 CCNA2; CDK2; ADRB2; MYBL2; DNMT1; TFDP1; EZH2; ERG; WHSC1; CHAF1B; BRCA1; FOXM1; RBL1; HOXB7; MBD2; GFI1; HOXC6; HMGB2; BAZ1A; PRKDC; ZEB1; TOX3; HOXC4; CHD7; BATF3; ZNF266; HNRNPD; HOXC10; NR1H3; IRF4; NFIB; BCLAF1; FOXD1; NR2F2; MYB; SUV39H1; INSM1; BHLHE41