Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16191 Pf-477736 GSE70138 MCF10A Human 24h 10uM EID0005
Types Number Response transcription factors
Up-regulation 53 TSC22D3; RFX5; PNRC1; SP110; CALCOCO1; TRIM22; TSG101; BPTF; IRF7; EGR1; NFIL3; SREBF2; CITED2; SP100; BTG1; TRIM29; ZNF195; TOB1; MED13; KLF5; ZNF331; SALL2; CREBL2; ELF3; AES; MYBL2; HOXD1; ZNF91; IRF9; ZBTB38; TAF10; NR4A2; HOXB2; HMGN3; MNDA; ZSCAN31; LMCD1; TLE4; TXNIP; ATF3; FOSB; MEIS1; JUP; SOX9; INSR; TFAP2C; SPDEF; ASCL1; PBX1; KLF4; FOS; MYB; WT1
Down-regulation 49 CCNA2; ADRB2; EZH2; FOSL1; PSMC3IP; CDK2; NRIP1; HMGA2; CHAF1B; FOXM1; CHD7; BAZ1B; CENPF; HMGB2; ERG; TAF1A; MLXIP; ZNF107; HIRA; CRY1; FOXE1; BIRC2; BLM; BRCA1; EYA2; CBFB; DNMT3B; TRRAP; GATA4; BACH2; BMI1; ZFP36L2; SHOX2; NKX2-2; ZEB1; HHEX; MYBL1; LEF1; CEBPG; HNRNPD; MSX1; HIC2; SOX17; ELF5; ZIC1; SUV39H1; SOX11; SATB1; ID1