Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16184 Roscovitine GSE70138 MCF10A Human 24h 0.04uM EID0005
Types Number Response transcription factors
Up-regulation 79 ADRB2; NFIL3; MNAT1; MTF2; WWP1; TOPORS; JUN; RRN3; NR4A3; ZNF184; CDC5L; ZSCAN16; ZNF140; MED13; MECOM; FOXF2; SMAD2; PNRC1; DACH1; ISL1; PBRM1; TCEB2; TBX2; HEY2; TSC22D2; MDM2; SUB1; MAZ; SKI; ZNF623; ZNF165; AHR; TCF12; TFEC; FOXF1; SOX11; ZBTB20; ZNF189; HLX; ZSCAN31; CREBL2; PRKDC; NR4A2; SATB2; ID4; NR3C2; RAD21; SFPQ; NR2F1; TCF4; ATF3; KAT2B; MEOX2; ELF3; MXI1; TWIST1; TXNIP; OSR2; MSX1; TOB1; PIR; ETS2; CALR; AEBP1; NR4A1; HMGB3; BHLHE41; EGR2; PURA; KLF4; PITX1; PBX1; ZFP36L1; ASCL1; TGIF1; ELK3; POU2AF1; LEF1; TLE4
Down-regulation 38 PHF20; ZNF44; APEX1; PFDN5; TCF25; TP53; RELA; PPRC1; BASP1; GTF3A; ZNF239; MNT; NKX3-1; STAT5A; RBPJ; ZNF281; E2F8; KMT2A; ZNF91; YWHAB; SMARCA1; HOXD1; SPEN; STAT3; TRIM29; ZBED2; SCAND1; MAGED1; KLF6; BCL11A; HOXB6; MYCN; MYRF; FOXG1; FOS; PEG3; TSC22D1; KDM5D