Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16183 Roscovitine GSE70138 MCF10A Human 24h 0.12uM EID0005
Types Number Response transcription factors
Up-regulation 64 PAX8; NFKB2; HIRA; JUNB; ESR1; NAB1; ISL1; MTF2; PHIP; ZNF217; NFAT5; SOX17; FUBP1; TRIM29; ZNF136; FOXO3; EMX2; ZKSCAN7; MED23; MEIS1; ELF2; FOXE1; MEOX1; ZNF248; BAZ2B; ERBB4; CREB3L2; ZBTB20; JUP; ESRRG; BRD3; ZSCAN18; HDAC9; TSC22D1; ID4; ZNF331; TXNIP; ZBTB38; ING3; NR0B1; BBX; PEG3; ELF5; WT1; SALL1; DACH1; NR4A2; ZBED2; ATF3; CUX2; ZFPM2; HEY2; ST18; TCF4; ZFP36L1; IRF6; HOXB2; ZNF423; TRIB3; ASCL1; LEF1; BHLHE41; ARNT2; FOS
Down-regulation 29 CRK; ZNF281; MNT; SF1; C1QBP; BATF; HMGA1; ZNF394; KLF6; MAFF; RBPMS; IL16; CENPF; CD3D; IRF4; ZNF432; IRX5; ETS1; ENO1; PIR; PCGF2; RUNX1; POU2AF1; GATA6; ZBTB18; STAT5B; KLF9; FOXG1; SATB1