Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16182 Roscovitine GSE70138 MCF10A Human 24h 0.37uM EID0005
Types Number Response transcription factors
Up-regulation 17 RFX5; CTR9; TSG101; DEAF1; ZNF195; SIX1; SOX11; HTATIP2; FOXA1; FOXJ3; HMGB3; HMGN3; TSC22D1; LEF1; POU2AF1; FOS; MAFB
Down-regulation 29 PHF1; EPAS1; GATA6; MYRF; FLNA; TCF21; ZNF331; PAX6; BNC2; RUNX1; CREM; LMCD1; EMX2; CALR; EHF; TRIB3; IRF6; BCL11A; ST18; INSM1; HOXB7; AEBP1; ESR1; HOXB6; VPS72; KLF9; MEIS2; KLF4; STAT5B