Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16180 Roscovitine GSE70138 MCF10A Human 24h 3.33uM EID0005
Types Number Response transcription factors
Up-regulation 25 RFX5; SUB1; CREB3L2; PHIP; CHD7; ZNF217; IRF2; BMI1; BAZ2B; NKX2-1; FOXO1; SP3; IFI16; ZBTB20; RYBP; HHEX; POU2AF1; KLF2; NR1D2; HMGN3; TAL1; DACH1; TXNIP; ASCL1; EGR2
Down-regulation 19 MAX; PHF20; MED21; PFDN5; HMGA1; SMAD1; FOXG1; SOX9; FLNA; HOXC10; TRPS1; EYA2; ZIC1; SAP30; MEIS1; TOX; HOXC6; SATB1; ZBTB18