Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16178 Torin-2 GSE70138 MCF10A Human 24h 0.04uM EID0005
Types Number Response transcription factors
Up-regulation 249 TSC22D3; CALCOCO1; SOX4; CAMTA2; CBX7; GLI2; EP300; ZNF688; HAND1; HBP1; SPI1; RING1; ZNF536; CREBL2; L3MBTL1; ZNF611; ZMYND8; NEUROD1; TBX6; ZNF43; CDIP1; ZNF665; ZNF195; ZBTB44; PHF1; ZFHX2; MZF1; HINFP; MNT; ZSCAN9; ZBTB7A; ZBTB43; PNRC1; ARID1A; AFF2; ESR2; SRCAP; ZNF93; NCOA3; NHLH2; THRB; CIITA; TADA3; NAB2; TGFB1I1; ZFP2; NFIX; TCF21; ST18; ZNF91; HMGA2; YEATS2; EZH1; ZNF136; ZNF135; ZNF667; ING4; TBPL1; ZNF816; CUX1; MECP2; ELF4; E2F2; CARF; ZNF224; ZNF133; ZNF500; BAZ2B; ZNF33B; ZIC3; SUPT3H; ZFPM2; ZNF337; TSG101; NHLH1; ZNF3; ZNF85; MEIS1; LIN28A; TSHZ2; MDM2; TCEB2; ZNF44; ZNF573; MAFF; ZNF83; LZTR1; ZNF160; SSBP3; ZNF264; RBPJ; PAX6; ZNF117; ZFHX3; PHOX2B; ZNF239; ZBTB20; SCAI; ZMIZ1; CBX4; ZNF506; ZNF202; BRWD1; TFEC; CIR1; ZNF835; SOX2; INSM1; ZNF415; PCGF3; DDX17; MAK; ZNF362; KMT2A; VENTX; ZKSCAN4; GBX1; TRAK1; PEG3; BPTF; GATA3; NKX3-2; BNC2; FEZF2; CBFA2T3; PRDM2; TEAD3; JAK2; TCEA2; ZNF358; KLF7; BTG1; CSDC2; ZNF467; FOXN3; ZNF112; JUP; ZNF345; IRF8; NFKB2; IRF6; ZNF654; ZNF682; ZNF175; CTBP1; ZNF426; HLX; BACH1; ZNF334; HDAC9; MXI1; KAT2B; ZNF423; ZBED2; GATA6; HDAC5; FOXO3; PFDN5; SMARCC2; TAL1; GATA2; PRDM12; IRF9; ZNF354A; HOXD3; SNAI2; RARG; SALL2; GLI3; HMBOX1; CBX6; TCF7L2; ACTL6B; ZKSCAN7; HLF; NFAT5; TULP3; SOX17; ATN1; HIPK2; BASP1; HIC2; RBFOX2; HTATIP2; REL; MAF; AES; CREB3L2; SOX3; STAT6; AHR; ZNF711; JUND; IRF1; JUNB; CHD3; ZNF331; BCL11A; CUX2; SHOX2; CITED2; ZKSCAN1; INSR; ZNF430; LMCD1; COPS2; PAWR; ESR1; IKZF1; ZNF302; OSR2; KAT6B; MEIS2; HOXD1; FOXF2; BCL6; ZFP36L1; BCL3; ZFP36L2; PLAGL1; ATF3; ERBB4; MYRF; ZNF652; KLF4; RSF1; EMX2; TCF4; MEOX2; WT1; EHF; KLF6; FOSB; ZBTB16; TGFB1; MNDA; SSX1; TRIM29; BACH2; MYCN; ZEB2; KLF11; CREB1; ARNT2; NFATC4; FOS; BHLHE41; KDM5D; MAFB
Down-regulation 83 CCNA2; EZH2; MYBL2; TFDP1; HOXA5; MYCBP; TCERG1; FOSL1; BRCA1; PDLIM1; NUP62; RHOA; RUVBL1; CENPF; TFAM; CBFB; DEK; CCNC; CHAF1B; CEBPD; CDK2; GMNN; TAF9B; PSMC3IP; MED6; HMGB2; CRY1; BCLAF1; RUVBL2; PTTG1; RBBP4; HMGB1; SFPQ; FOXM1; TRIM28; HNRNPD; WWTR1; ITGB3BP; BMI1; STAT3; TOB1; ZNF200; PMF1; SUB1; SMAD5; RBM14; RAD21; HLTF; HOXB7; ENO1; HDAC1; BLM; BHLHE40; PIR; RBBP7; RNF6; ILF2; PRKDC; RAN; STAT1; SUV39H1; ING2; SAP30; RBBP8; PSMC3; SMAD1; MAGED1; PUF60; HOXC10; MED1; NR2F1; POU4F1; DNMT3B; HMGB3; EGR3; NFIB; AFF1; IRX5; HOXC6; FOXG1; LEF1; ZBTB18; TCFL5