Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16174 Torin-2 GSE70138 MCF10A Human 24h 3.33uM EID0005
Types Number Response transcription factors
Up-regulation 408 TSC22D3; CALCOCO1; HBP1; PNRC1; EZH1; ATF4; EP300; ZNF688; HINFP; SOX4; GATA2; BTG1; ZNF671; HDAC5; IRF9; ZNF91; CDIP1; ING4; ZNF33B; CBFA2T2; ZNF224; CEBPD; ZNF117; RFX1; GLI2; ZNF611; PHIP; ESR2; SUPT5H; ZNF500; ZNF304; SRCAP; ZNF667; ZNF154; PRDM14; CREBL2; CBX7; ZNF160; NEUROD6; THRB; L3MBTL1; ZNF268; MECP2; EED; ZNF264; CAMTA2; LHX3; ZKSCAN4; PRDM2; ZNF135; TBX6; IRF7; RFX3; MZF1; ZNF223; FEZF2; ZNF43; ZNF419; ZBTB44; GON4L; CIR1; DLX4; ZNF292; PHF1; ASCL3; CARF; MED12; ARID5A; ZNF133; ZNF506; TBX4; BARX1; STAT2; ZNF93; SALL2; ZNF665; ZNF573; ZNF175; RBPJL; ZNF536; E4F1; PLAG1; AFF2; ZNF606; NAB2; BPTF; PRDM9; MED13; ZFHX2; CHD2; HOXB1; HNF4G; SOX18; SOX17; SCAI; ZNF701; ZNF257; GCM1; TBX19; ZNF235; LZTR1; ZBTB3; NR5A1; CITED2; CRX; KAT2B; ZNF112; ZNF219; ZNF507; ZNF586; TLX1; BRD4; YEATS2; ZNF589; ZNF362; ZNF177; PBXIP1; FOXE3; ZNF682; ZNF208; RCOR3; ZNF345; PRDM10; IKZF3; POU2F3; ZNF669; KLF8; ZNF358; ZNF768; KLF13; ELF4; BACH1; RORC; NR1H2; HESX1; VENTX; MDM4; TBX5; ZNF549; PPP1R13L; NHLH1; LMO1; ZBTB7A; ZNF814; BAZ2A; GRHL2; CERS4; RING1; CIC; ZIC3; SOX3; ZNF440; PEX14; ZNF211; TCEA2; GBX2; IRF6; ZNF816; BRWD1; POU1F1; HIF3A; SETDB1; ZSCAN18; PKNOX2; SP100; DLX5; MKL1; TBX21; MAML3; MEF2C; ID4; DCC; FOXD3; ZSCAN9; PRMT2; POU6F2; E2F2; PRDM12; APBB1; HOXD13; MXI1; DYRK1B; MYF5; ZNF334; SUPT6H; ATF2; KMT2A; ARID4A; GBX1; MXD3; SOX10; TEAD3; ZNF444; SOX21; ZNF354A; ZNF254; TCF25; MNT; ZNF350; ZNF155; TSG101; ZNF140; PAX4; FOXJ2; TCF7L1; ZNF623; PRDM13; IRF8; GATA3; NEUROG2; ZNF214; MED23; AES; NKX3-2; STAT4; TAF6L; LDB1; ZMYND8; LIN28A; SMARCC2; THAP9; ZNF132; MED14; SPI1; ZNF80; SCRT1; ZNF426; SIX6; CBX4; ZNF331; HEY2; SNAPC4; NPAS2; TULP1; ZNF695; TBX1; MED25; ZNF529; OVOL2; TRIM29; ZBTB17; CTBP1; NFIX; NEUROD2; ZZZ3; ZNF202; ATOH1; PROP1; ZNF81; ZNF225; HSF4; FOXO1; IRX4; LMCD1; NFKB2; PRDM1; AEBP1; SUPT3H; ZNF329; ZNF674; CEBPE; VGLL1; HDAC9; NCOA2; ZNF675; ZBTB20; ZNF83; ZNF75D; HSF1; SP110; TP63; KDM5C; ST18; CREB3L2; ZBTB16; AR; RARG; ZNF532; ARID1A; BACH2; BCL11A; ZNF415; ZNF195; ERBB2; ZNF580; ZKSCAN1; HMBOX1; TFAP2A; TULP3; JUP; TRPS1; TRIP4; SIN3B; ELF5; ZNF85; TXNIP; CDK9; MDM2; PCGF3; ZFHX3; ZKSCAN7; TFEC; TCF7L2; DDIT3; FOXO3; ZNF34; SRY; ZNF141; TRIM22; TLE2; MBD4; CUX2; TP73; RORA; IKZF1; EPAS1; JAK2; HOXD1; CHD9; ZSCAN16; ZHX2; MED17; PSPC1; TGFB1I1; NEUROD1; KLF7; ERBB4; NR2C1; SOX2; HMGA1; TERF2; HOXB2; ZNF423; TAL1; HOXD3; NR5A2; EYA1; E2F5; SMARCA1; JUND; HOXB13; ZBED2; HTATIP2; CBFA2T3; EN1; FOXF2; PITX2; WNT4; TGFB1; RSF1; ZNF512B; PAWR; KLF5; TCF4; DDX17; TFAP2C; CHD8; ACTL6B; GTF2IRD1; MAFF; INSM1; MEOX2; ZNF711; ESR1; EHF; ZNF217; ZNF430; ZNF12; FOXN3; FLI1; BNC2; NR1H4; ZNF232; STAT3; NANOG; BHLHE41; OLIG2; INSR; ARNT2; SALL1; CTBP2; NFATC4; TRIB3; KLF11; SNAI2; POU2AF1; NFATC3; FLNA; IRF1; MYBL1; FOXO4; BCL3; TOX3; NFE2L3; MAFB; ZIC1; FOSB; CREB1; PBX1; KDM5D; MEIS2; HMG20B; MAF; RELB; TLE4; FOS; MYRF; BASP1
Down-regulation 102 ADRB2; CCNA2; MYCBP; FOSL1; PARP1; TFDP1; EZH2; GTF2A2; RUVBL1; NUP62; RBBP4; MYBL2; HDAC2; DRAP1; MYC; TCERG1; CBFB; BMI1; RUVBL2; TBP; HLTF; GMNN; ETV1; C1QBP; TFAM; PA2G4; RHOA; HSBP1; CTR9; RNF138; DNAJC2; EGR1; SUB1; BCLAF1; RBM14; BRCA1; ITGB3BP; ECD; MED21; PIAS2; CHD1; RBBP7; SMARCA4; MED6; HDAC1; ENO1; TAF9B; PSIP1; TRIM28; IKBKAP; SMAD5; NFYA; SFPQ; JARID2; BAZ1A; NEDD8; ATF1; ZNF146; CCDC59; HOXA10; ID2; RAN; SSRP1; PMS1; HMGB2; ZBTB38; SMAD1; MTDH; ELK3; HOXC6; HOXB7; HNRNPD; BLM; PTTG1; RNF14; HMGB1; DEK; ING2; RBBP8; ZBTB18; LOXL2; YWHAB; LEF1; EGR3; TRIM32; IRX5; CALR; PITX1; NR2F2; SUV39H1; PURA; HOXC10; HES1; HMGB3; NR2F1; PIR; ID3; PUF60; MYB; ID1; STAT5B; TCFL5