Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16172 Pelitinib GSE70138 MCF10A Human 24h 0.12uM EID0005
Types Number Response transcription factors
Up-regulation 227 CALCOCO1; RFX5; NFKBIA; PBXIP1; SCMH1; ZNF268; PNRC1; SOX4; KDM5B; ZNF195; ZNF688; AR; ZNF768; ZNF117; ING4; TSHZ2; AES; CREBL2; ELF4; ARID5A; OSR2; ZNF652; WNT4; HDAC5; SP110; STAT2; NCOA3; MZF1; VGLL4; IRF9; ZNF611; BPTF; NR5A1; TCEB2; YEATS2; CREB3L2; ZNF43; SRCAP; CIR1; HBP1; CBFA2T3; ZMYM2; ID3; ELF3; TFEC; NCOA2; SUPT6H; PHIP; PRDM2; ATF4; TGIF2; ZNF665; CUX1; ZNF136; ZNF33B; ARID5B; ZSCAN31; ZSCAN32; MED12; BTG1; ZNF224; ZNF44; MECP2; CDIP1; CBX7; SETDB1; TAF7; KAT2B; REPIN1; CARF; SIM1; SREBF2; CEBPD; ZNF85; MAML3; CSDC2; DLX4; KDM4A; DYRK1B; MECOM; ZNF263; CIITA; TRIM22; MEIS1; TRIM29; FOXK2; ZNF155; THRA; SALL2; EZH1; MYCL; JUP; SP140; SUMO1; HDAC9; MYF5; ZBTB3; RARB; TRIM16; ZNF91; ESRRA; ZNF34; LITAF; PKNOX2; UBE2B; L3MBTL1; NFIL3; DDX17; ZNF345; HESX1; ATF3; GATA3; E2F2; SSBP3; SP140L; ERBB2; ZHX2; ZNF362; IRF6; ZNF160; SREBF1; MNDA; PCGF3; TP63; ZFPM2; ATF7IP; LYL1; FOXN3; ZNF500; OVOL2; ZNF350; CBX4; TCF7L2; GATA6; LDB1; ZNF124; EHF; KAT8; DAXX; SOX3; JAK2; TCF12; BHLHE41; MXI1; E2F5; INSR; ZNF112; ESR1; MEOX2; TRIM24; TWIST1; SMARCC2; PCGF2; TRPS1; NFE2; GRHL2; PEX14; PDLIM1; ARID1A; TERF1; REL; ZNF354A; ZNF141; FOXO1; KLF5; PEG3; RORA; HMBOX1; SNAI2; ZNF512B; FOXO3; ZFP36L2; TCEA2; HIC2; FLI1; ZNF430; NR5A2; ZNF467; TAL1; HMGN3; LMCD1; NR1H3; ZNF711; MYCN; CERS4; IRF1; CERS6; HTATIP2; ZBED2; ZNF264; SMAD1; JUNB; SMAD6; PAWR; FOSL2; TFAP2C; NKX2-1; ZBTB1; SOX17; EMX2; BCL11A; AEBP1; SMARCA1; FOXF2; TRIB3; ZNF423; VPS72; HEY2; TOX3; NANOG; HOXD1; TLE1; HEY1; MEIS2; FOSB; ARNT2; TCF4; TOX; ID4; MAF; INSM1; WT1; PBX1; SSBP2; FOXO4; NFATC4; ID1
Down-regulation 84 CCNA2; FOSL1; HMGA2; EZH2; PSMC3IP; WHSC1; CDK2; MTF2; FOXM1; EGR1; TFDP1; BRCA1; DNMT1; DRAP1; FHL2; MYBL2; PARP1; RUVBL2; CENPF; NUP62; TCERG1; HMGB2; ETV1; HOXA5; CHAF1B; ING3; HDAC2; PTTG1; TAF5; TRIM28; RBL1; GMNN; BAZ1A; TFAM; PA2G4; EED; BLM; CBFB; ELK1; SAP30; EGR3; NELFB; DEK; HNRNPD; HMGA1; RBM14; XBP1; TAF1A; SUV39H1; RNF4; TOPORS; RB1; NFIB; SSRP1; BCLAF1; TDP2; HSF2; ETS1; PREB; NR2F1; MYBL1; HLTF; ILF2; SOX9; NR2F2; YWHAB; PSIP1; HOXC6; TSC22D2; AGO2; MED1; RBBP8; KLF2; RUNX3; ELK3; SFPQ; HMGB3; ZFP36L1; HMGB1; TGFB1; KLF9; CREB1; PPARG; EGR2