Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16171 Pelitinib GSE70138 MCF10A Human 24h 0.37uM EID0005
Types Number Response transcription factors
Up-regulation 410 NR3C1; TSC22D3; CALCOCO1; ZNF33B; GATA3; ZNF586; MZF1; TRIM29; EZH1; ARID5B; HINFP; IRF9; GLI2; ZSCAN9; ZBTB44; NR1H2; SALL2; ZFHX3; AR; ZNF611; NCOA2; WNT4; TRPS1; ZNF467; HBP1; ZNF606; ZKSCAN4; PHIP; PNRC1; ZNF350; ID4; ZNF268; ZNF337; TP63; ZNF44; ZNF768; OSR2; NR6A1; RFX1; ING4; ZNF224; ZNF304; SOX12; ZNF331; HNF4G; ZSCAN31; ZNF688; ZNF652; PRDM14; CIITA; RORC; SOX13; ZBTB3; THRB; BPTF; ZNF701; CUX1; ZNF136; ZXDC; HOXB3; HDAC5; TAF1C; ZNF135; FOXH1; THAP7; AFF2; EYA3; ZNF165; RBPJL; SRCAP; ARID5A; NR5A1; NEUROG3; CERS4; NR0B2; ZIC3; ZNF816; ZNF667; HLX; CBFA2T3; ASCL3; L3MBTL1; ZNF254; TSHZ2; BRWD1; SETDB1; SOX18; LZTR1; RFX3; PBXIP1; HIVEP1; ZKSCAN8; GRHL2; ERBB4; SUPT3H; ZNF85; ZNF195; SOX3; ZNF669; ZNF223; ZBTB20; KAT2B; ZNF665; HIF3A; GFI1; HESX1; HDAC9; HOXB1; EP300; MAML3; BACH1; LHX3; JAK2; PRDM2; POU2F3; NKX2-5; ZNF91; KLF1; CUX2; TCEA2; ZNF778; SUPT7L; ZNF235; ZNF814; SSBP3; TCF4; BCL11A; CIR1; ZNF423; MKL1; ZNF75D; ZNF154; SIX3; NCOR1; IRF6; POU2F1; STAT4; BAZ2B; ZNF257; ESR2; ZNF117; PPP1R13L; NFE2L2; MYCL; CHD9; GON4L; HDAC6; ZNF264; ELF3; CEBPD; OVOL1; MEIS1; TBL1X; MED12; ZNF771; SIM1; RING1; FOXI1; MTF1; ELF4; ZNF112; ARID1A; TBX4; ZNF529; ZNF426; TBX1; ZNF43; POU1F1; ZNF492; NR1I3; TFAP2A; REL; DLX5; HOXB2; ZNF133; TFDP2; ESR1; ZNF362; SIN3B; RARG; ZNF248; CREB5; ZNF506; EMX1; SPI1; ZNF93; MNX1; RAX; PRDM10; PRDM1; TP73; SOX5; MECP2; CARF; KDM4A; ZNF202; CRTC1; TBX19; BCOR; ZFPM2; TRIM16; DYRK1B; GBX1; TFEB; IKZF3; KMT2A; NFAT5; HSF4; HOXD9; MXD4; TFEC; TEAD3; VENTX; BARX1; ZNF24; ZNF225; MED14; ARID3B; TOX3; CHD2; ZNF141; ZNF682; DLX4; ZSCAN18; MDM2; SOX17; LYL1; EHMT2; KLF3; PAX1; VGLL1; ZNF574; BCL6; ZNF329; ZSCAN16; PEG3; ZNF274; DACH1; MYF5; FOXO3; ZNF580; ZHX2; PLAG1; THRA; FOXN3; INSM1; NR5A2; TCF25; ATOH1; ZNF675; ZKSCAN1; NEUROD1; ZNF14; RSF1; SOX2; ZNF493; HIRA; ZNF80; MEOX1; ZNF573; ZNF430; NFE2; ZNF219; MEIS2; PIAS1; ZNF721; SCAI; MXI1; HOXD13; CBX7; MNT; PRDM12; ZMYND8; BRD7; ZNF345; LMCD1; SOHLH2; CSDC2; IRF8; ZNF674; LIN28A; ZNF205; ZNF83; AEBP1; MGA; MEOX2; FOXA2; ZNF34; ZNF354A; AES; ZFP36L2; ZNF544; ZNF551; OVOL2; RXRA; DMRT1; EBF2; PAWR; ZNF711; ZNF589; EHF; TCEB2; PKNOX2; TCF7L2; CREBL2; ZNF160; YAP1; GATA6; E2F5; HMBOX1; JUP; ZBTB16; FUBP1; PAX6; KDM4C; RORA; MYRF; ATF3; EPAS1; ARL2BP; NFKB2; MBD4; ZNF623; ELF5; TCF21; EMX2; ST18; SALL1; ZNF358; HLF; TAF1D; TAF1; PEX14; ZNF444; PFDN5; SKI; MNDA; ZNF273; TRIM22; NCOA1; WWP1; ZMIZ1; HOXB5; LDB1; ZNF415; TCF7L1; TLE2; SIAH2; TRIB3; ZNF532; TFAP2C; PGR; FOSL2; HIC2; RBL2; ATN1; NHLH2; ZNF432; BTG1; BNC2; SNAI2; FOXA1; NFE2L3; MYCN; GATA2; EYA1; ID3; TULP3; SMARCC2; JUND; CREB3L2; AHR; VDR; HOXD11; ISL1; MAF; CD3D; ARID4B; HOXB6; HEY1; ESRRG; NFATC3; BACH2; TLE4; TRIM24; PBX1; ARNT2; IRF1; LITAF; BHLHE41; ZNF266; NR1H4; ZIC1; NFATC4; FOXG1; MAFB; ID1; PLAGL1; NANOG; WT1; INSR; HIPK1; PIR; ZNF512B; SPDEF; SSBP2; KLF4; VPS72; TSC22D1; FOS
Down-regulation 119 CCNA2; FOSL1; HMGA2; EZH2; TFDP1; PSMC3IP; DRAP1; EGR1; CTR9; PARP1; FHL2; RHOA; MYCBP; HDAC2; MYC; BMI1; UBE2I; TBP; RUVBL1; RBL1; RBBP4; WHSC1; NUP62; TCERG1; KMT5A; BRCA1; CHAF1B; CENPF; DEK; SUB1; BAZ1A; FOXM1; HMGB2; BCLAF1; HNRNPD; MYBL2; PTTG1; EGR3; EED; SAP30; WDHD1; HLTF; RNF4; CBFB; TAF9; NPM1; BAZ1B; CCNC; RBM14; BATF3; SMARCA5; CREG1; GABPB1; ZMYND11; RAN; SFPQ; SMARCE1; ZNF146; MAFF; PA2G4; ING3; TRIM32; C1D; UBP1; NELFB; HMGB1; MNAT1; SUV39H1; JUNB; NRIP1; ING2; BLM; ITGB3BP; CALR; YWHAB; TRIP6; TSC22D2; ARNTL; TBL1XR1; HOXA1; RUVBL2; HOXC6; SMARCA2; ZBTB38; PIAS2; ELF1; MED1; CCDC59; RNF138; CBX3; ZNF302; KLF2; CITED2; MAGED1; ELK3; SMAD3; FOXD1; HMGA1; RBPMS; NKX3-1; ZNF281; BCL11B; HOXC10; HIPK3; RUNX1; AFF1; DNMT3B; NR2F2; PURA; MYB; HMGB3; LEF1; TCFL5; SOX9; PUF60; ZBTB18; STAT5B; ASCL1; KDM5D