Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16170 Pelitinib GSE70138 MCF10A Human 24h 1.11uM EID0005
Types Number Response transcription factors
Up-regulation 226 TSC22D3; ZNF274; ARID5B; CALCOCO1; ZNF33B; ZNF688; ZNF268; PNRC1; TRIM29; IRF9; KLF1; MZF1; ZNF91; MED16; ZNF606; ZNF83; ZNF304; HBP1; ZNF611; DLX4; ZNF665; HDAC6; ZNF544; NCOA3; ZMYM2; ZNF419; TRPS1; ZBTB48; EZH1; ZNF768; ZNF134; TRIM16; SOX4; BAZ2B; HDAC5; SUPT7L; BPTF; ZNF467; ZNF667; ZNF217; ZNF85; KDM4A; ZNF135; EP300; ZNF131; L3MBTL1; MED12; ZNF44; ARHGAP35; TSHZ2; RARG; NR1H2; ZNF329; ZNF117; ZNF224; LDB1; SMARCD3; ZNF652; RING1; HINFP; ELF4; CARF; TBX4; WNT4; MXD4; ZNF84; SREBF1; GATA6; HSF4; ZNF350; ID2; CDIP1; TCEA2; ZNF358; ZNF12; BCL11A; ZSCAN18; MYCN; DAXX; ZMYND8; GATA1; SIX3; AES; RARA; CBX7; CSDC2; RFXANK; ZNF160; ZNF500; NFE2L1; CEBPD; ZNF140; CIR1; TFEC; ZKSCAN4; NFIL3; DDIT3; TRIM22; NCOA2; MKL1; ZNF195; ZNF112; PHF20; LMCD1; ZKSCAN1; IRF6; SALL2; WIZ; PBXIP1; GFI1B; HOXB1; EBF2; ATF3; TWIST1; ING4; ARID3B; ZNF257; KLF3; EPAS1; NFE2; ZNF165; ZNF248; ELF3; ZNF93; ZNF136; ZNF219; ZNF331; INSR; ZNF175; BACH1; TP73; FOSL2; TLE2; SCAI; ZNF264; HOXB13; PRDM2; TEAD3; SP140; TP63; THRA; PRRX2; TFAP2A; DLX5; ZIC3; TRIM24; ZNF587; ZNF141; PEX14; RNF10; TRIB3; DDX17; LYL1; TCF7L1; ZSCAN31; IL16; ZHX2; FOXN3; ATF7IP; CUX2; TCEB2; CBFA2T3; FOXO3; ERBB4; BCL6; WWC1; MED13; AHR; GLI2; HLF; DACH1; MXI1; TP53; PBX1; NR5A2; BATF; CSDE1; MECOM; MEN1; OSR2; RYBP; MAF; NCOA1; TXNIP; VGLL1; ZNF415; HMBOX1; PDLIM1; SOX2; MEIS1; ZBTB16; ZNF711; HEY1; BTG1; MNDA; HMGN3; SNAI2; KLF13; ZNF423; EYA1; TLE1; KAT2B; MEIS2; TGIF1; POU2AF1; TCF4; ELF5; FOXF2; ARNT2; JUP; MYCL; CREG1; HTATIP2; HOXD1; TAL1; BACH2; ESR1; VPS72; ZFPM2; TFAP2C; MYRF; ZBTB18; NFATC3; NFATC4; BHLHE41; FOXO4
Down-regulation 98 CCNA2; FOSL1; HMGA2; MYCBP; TFDP1; PSMC3IP; EZH2; FHL2; DNMT1; DRAP1; EGR1; HDAC2; PA2G4; WWTR1; PARP1; MYBL2; HMGA1; TBP; MYC; FOXM1; NUP62; RBL1; CDK2; EED; BRCA1; BCLAF1; YEATS4; TCERG1; GMNN; RUVBL1; ZNF143; BMI1; SUB1; ETV1; BAZ1A; TRIM28; BIRC2; SSRP1; RNF4; PPRC1; KMT5A; SF1; CENPF; CTR9; TOPORS; POLR3F; NFYA; C1QBP; UBE2I; CBFB; MAX; BAZ1B; ETV5; MAFF; RB1; FOXD1; TAF9B; HNRNPD; ATF5; PTTG1; BATF3; DEK; NPM1; PHF2; NR2F2; UBP1; ELK3; RUVBL2; HMGB2; HOXB7; NFIB; RNF138; SFPQ; CHD7; SATB2; RBM14; CALR; GATAD2A; HLTF; HHEX; SMAD2; HMGB1; SUV39H1; PRKDC; HDAC4; JUNB; YWHAB; HOXC6; KDM5D; EGR3; MYBL1; NKX2-2; RBPMS; MSX1; PURA; CREB1; BASP1; SATB1