Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16169 Pelitinib GSE70138 MCF10A Human 24h 3.33uM EID0005
Types Number Response transcription factors
Up-regulation 195 TSC22D3; IKZF1; ATF4; TRIM29; CALCOCO1; PNRC1; PBXIP1; OSR2; ELF3; ZNF33B; NR3C1; TRIM16; HDAC5; ZNF165; ZNF195; SREBF2; HDAC6; CIITA; NCOA3; KDM5A; ZSCAN31; ZNF768; ING4; SIX3; ZNF268; TRPS1; SOX12; KLF5; VGLL4; ATF3; KDM4A; NFIL3; NKX2-5; ZMYM2; ZNF529; PAX9; HOXB3; TP63; HNF4G; NCOA2; MYF5; MKL1; ZBTB3; SOX4; RFX5; ZNF688; CEBPD; IRF6; PIR; EHF; OVOL2; GATA6; LIN28A; ZKSCAN4; XBP1; JUP; BPTF; CEBPA; FOXJ3; ZNF34; KLF3; CARF; BCL6; BCOR; PHIP; MNT; TXNIP; ZNF254; TRAK1; DLX4; ZNF358; INSR; ZNF80; SNAI2; WNT4; GRHL2; EBF2; HESX1; POU5F1B; ELF5; ZNF83; SIM1; TRIM22; BCL11A; YBX1; DDX17; EYA2; DDIT3; STAT5A; KLF4; HTATIP2; MEIS1; FOXO3; SOX10; ZNF75D; TOX; ZNF226; MXI1; MEF2C; ZNF141; CNOT1; ZNF117; TBX1; CBX7; ZIC3; DNMT3B; HLF; SOX3; ZNF160; ZSCAN16; TCEA1; VGLL1; HMGN3; HBP1; EMX2; ZNF682; NR0B2; LYL1; NFE2L1; ZNF345; LMCD1; NFATC1; CEBPG; SOX17; LITAF; PDLIM1; MEOX2; FOXJ1; TFDP2; PCGF2; TRIB3; FOXF2; BTG1; FOXA1; HEY1; CREB5; PAX5; RORA; FOSB; KAT2B; CERS4; BACH2; EN1; ISL1; E2F5; FOXC1; TCF7L1; IRF9; ZNF711; TRIM24; RSF1; ERBB2; FOXG1; PEG3; HOXD1; ZNF124; TCEA2; TOB1; NR5A2; MEIS2; TCF7L2; TOX3; PBX1; DLX5; TLE1; FOXF1; CREG1; SMAD6; SIX2; INSM1; FOXN3; ZHX2; HIC2; ZIC1; POU2AF1; NR1H4; ZSCAN18; ZNF423; IRX5; ASCL1; SSBP2; ESR1; ARNT2; FOSL2; MYRF; AHR; ARID4B; TFAP2C; MAF; TGIF1; STAT5B; KLF11; MAFB; FOXO4; ID1
Down-regulation 91 CCNA2; FOSL1; HMGA2; DNMT1; MYBL2; EGR1; TFDP1; EZH2; PSMC3IP; ETV1; MTF2; MYC; GMNN; DRAP1; MYCBP; PARP1; BRCA1; RUVBL1; WHSC1; CENPF; TCERG1; HMGB2; FHL2; FOXM1; NUP62; CHAF1B; UBE2I; ING3; EED; HDAC2; RUVBL2; PA2G4; CAPN15; BAZ1B; NPM1; TFAM; CBX5; ZNF576; POLR3F; CCNC; TRIM27; DDX54; BRPF1; TRIM28; EGR3; NFKB1; PREB; SOX9; NELFB; BAZ1A; ZEB1; PTTG1; HNRNPD; RB1; NR2F6; SUZ12; PPRC1; RNF4; DEK; BLM; YWHAB; BCLAF1; CBFB; ELK3; SUV39H1; SSRP1; RNF138; RAN; BMI1; C1QBP; RBM14; HOXB7; HMGB1; TSC22D2; CALR; TRIP6; BATF3; CREB1; ING2; PPARG; HHEX; NR2F2; SFPQ; FOXD1; TGFB1; PURA; BASP1; RELB; MYBL1; SATB1; KDM5D