Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16168 Pelitinib GSE70138 MCF10A Human 24h 10uM EID0005
Types Number Response transcription factors
Up-regulation 227 TSC22D3; CALCOCO1; HDAC6; PNRC1; MNAT1; RFX5; ZNF33B; ZNF117; PHIP; PBXIP1; ZNF91; TRIM29; ZNF652; ARID5B; ZNF43; ZNF44; ZNF224; ZNF665; SIAH2; ZNF264; ZNF136; NCOA3; ZNF611; OSR2; EZH1; CBX7; MECP2; BPTF; ZNF701; VGLL4; TCF7; SUPT7L; ZNF350; ZNF133; SAP130; ZIC3; STAT2; ELF4; ERBB4; ZNF688; ATF4; ZNF84; MED12; ZNF83; IRF9; ELF3; ING4; BAZ2A; ZNF586; ZNF606; KAT2B; SOX12; CDIP1; SMAD6; HBP1; ID2; TFDP2; NCOA2; DLX4; EMX2; ZNF135; PHF20; ZNF329; HOXA10; HMGN3; ZNF587; ZMYM2; CEBPZ; DACH1; ZNF160; SALL2; CBFA2T2; SOX4; ZSCAN9; TRIM16; ZNF304; ZMIZ1; TWIST1; ZNF768; ZNF14; L3MBTL1; BAZ2B; NR1H2; MKL2; AIP; PEX14; ID3; ZKSCAN4; PHF1; CARF; TFEC; MED13; PIAS1; TAF7; TULP3; ZSCAN31; RXRA; TRPS1; CIR1; E2F6; DDIT3; CUX1; ZNF184; TOB1; POU2F1; ZBTB3; ARID1A; KLF3; ZNF175; ESR1; ZNF85; ZSCAN18; SMARCC2; HTATIP2; ZNF12; PRDM2; FOXN3; ZNF331; HDAC5; MYCL; SRCAP; SOX17; ZNF711; HDAC9; BCL6; ARNT; JUP; FOXA1; TRIM22; RSF1; ZNF93; ZHX2; SOHLH2; LMCD1; PAX6; NFKB2; KLF13; ZNF226; TCEA2; BTG1; BHLHE40; TP63; OVOL2; LIN28A; ZNF141; TFAP2A; ZNF248; KLF5; PIR; TERF1; ZNF423; ZNF544; BRWD1; ZNF273; CBFA2T3; HOXB2; CREBL2; SOX3; KLF11; CERS4; ZNF165; BHLHE41; MAF; ERBB2; ZNF415; ZNF189; TOX; PBX1; NCOA1; SERTAD2; FOXC1; SREBF1; TXNIP; ATF7IP; ZNF124; HMBOX1; DBP; E2F5; TLE2; NFAT5; ZNF217; HMGB3; TRIM24; BNC2; FOSL2; RYBP; ZBTB20; ZFP36L2; ATF3; FOXO3; IRF6; ST18; MSX1; ID4; MXI1; ZFPM2; MEIS2; AEBP1; NCOR2; TCF7L1; NR1D2; MNDA; SPDEF; LITAF; CUX2; MEOX2; ARNT2; TRIB3; HOXD1; TLE1; INSR; HEY1; TGIF1; CREB1; BCL3; MEIS1; NFATC3; ID1; VPS72; SSBP2; TFAP2C; BASP1; HMG20B; FOXO4; MAFB; NFATC4; LEF1
Down-regulation 122 MYC; FOSL1; HMGA2; CCNA2; TFDP1; ADRB2; MYCBP; HDAC2; RUVBL1; EGR1; DRAP1; TCERG1; ETV1; C1QBP; NFKBIB; PARP1; EZH2; NPM1; PSMC3IP; FHL2; RNF138; ARNTL2; MTA2; MYBL2; DNMT1; SAFB2; EGR3; TBP; GTF2A2; PA2G4; PPRC1; CDK2; HMGA1; CHAF1B; BRCA1; EED; POLR3F; SF1; NOC2L; DR1; BAZ1A; BCLAF1; CBFB; RBL1; UBP1; BAZ1B; DNAJC2; SNIP1; RAN; HNRNPD; DDX54; TFAM; CAPN15; GMNN; CTR9; NUP62; BRPF1; XBP1; WHSC1; PSIP1; NFKB1; SFPQ; TGS1; CCDC59; PMS1; PRKDC; WWTR1; ZNF593; ATF1; MBD2; RUVBL2; SSRP1; ETV4; HMGB2; ETS1; YWHAB; MTDH; SMARCA2; GATAD2A; TRIM28; BMI1; JUNB; BIRC2; TSC22D2; DEK; HLTF; TRRAP; NRIP1; URI1; SMAD7; CCNC; ELK3; JARID2; CITED1; RBM14; DDX5; BLM; ETV5; IKBKAP; MAFF; HDAC1; MYB; MED24; PTRF; TGFB1; ACTL6A; TRIP6; NR2F2; MYT1L; HOXC6; PAX5; EGR2; HOXC10; EDF1; ZBTB18; NR2F1; IRF4; SUV39H1; STAT5B; PUF60; FOS; SATB1