Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16166 Azd-6482 GSE70138 MCF10A Human 24h 0.12uM EID0005
Types Number Response transcription factors
Up-regulation 45 DMTF1; TCF15; FOXO4; PBX2; MYOG; GLI1; SIX5; SIRT2; ZNF646; MSC; LHX1; ESR2; MLXIPL; NPAS2; TSC22D4; MEF2D; PBXIP1; EVX1; TCF21; BARX1; ZNF184; BTAF1; NKX3-2; HOXB13; SIM2; ZNF205; TEAD3; ZSCAN16; TERF1; BRD2; HMX1; ZNF91; BCL11A; FOXF1; POU2AF1; PEG3; HOXD1; SPDEF; MAGED1; IRF8; ZSCAN18; TBX3; LEF1; WT1; FOS
Down-regulation 18 NR2F6; MSX1; RBPMS; FOXM1; EGR1; RBL2; JUND; TAF9B; HIPK3; GTF3A; NEUROD1; KLF7; EGR2; VPS72; NKX2-1; MECOM; KLF11; SATB1