Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16163 Azd-6482 GSE70138 MCF10A Human 24h 10uM EID0005
Types Number Response transcription factors
Up-regulation 38 TSC22D3; HOXA10; ZNF665; TRIM29; ZNF117; PRMT2; ZNF611; MDM4; TRIM16; TP63; MNT; NR1D2; NCOA2; ZNF160; ZNF83; RBL2; TP53; HES1; SOX13; CHD9; TRIM22; BTG1; BBX; SATB1; BHLHE40; LITAF; TXNIP; FOXN3; ZFP36L1; IRF1; IRX5; HOXD1; SPDEF; ESR1; CREG1; ZNF91; SOX11; PITX1
Down-regulation 30 FOSL1; DRAP1; HMGA2; EGR1; E2F3; LMCD1; WWC1; IRF4; GATA4; ECD; NKX3-1; CSDE1; NFIB; ST18; JUN; HHEX; HEY1; MYT1L; SFPQ; RUNX3; CD3D; MED1; DLX2; IRF8; EGR3; VPS72; HOXB6; NR2F2; LEF1; KDM5D