Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16159 Tgx-221 GSE70138 MCF10A Human 24h 1.11uM EID0005
Types Number Response transcription factors
Up-regulation 15 RFX5; FOXO4; CRY1; MLXIPL; TSC22D4; TCF15; CTNNB1; CHD7; NR1D2; PIR; MYT1L; PEG3; TRIM29; WT1; FOS
Down-regulation 28 TWIST1; TGFB1I1; TFCP2L1; ISL1; APEX1; PITX2; NKX2-1; KLF4; ZEB1; PAWR; MECOM; TBX3; RBPMS; ZNF217; ZNF232; GATA6; CITED2; SOX11; ZFP36L1; LOXL2; TRIB3; ZNF423; ZNF512B; TFAP2C; CREB1; SOX9; PBX3; MYB