Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16156 Azd-8330 GSE70138 MCF10A Human 24h 0.04uM EID0005
Types Number Response transcription factors
Up-regulation 198 KDM5A; TSC22D3; NFKBIA; SOX4; ZNF33B; TRIM29; IRF9; CALCOCO1; PNRC1; PBXIP1; ZMIZ1; ARID5B; MXD4; NCOA3; CBX7; SRCAP; BTG1; SUPT7L; HDAC9; ADRB2; PCGF3; BPTF; SOX12; MZF1; TP63; ZNF665; EZH1; JUP; WWC1; CEBPD; NFE2L2; SALL2; ELF4; VGLL4; NCOA2; ZNF165; PHIP; ZFHX3; ID3; GATA3; WNT4; HBP1; ZNF224; ELF3; NR5A1; ZSCAN31; PPP1R13L; MEIS1; ING4; CDIP1; ZNF195; OSR2; CREBL2; LHX3; HDAC5; OVOL2; NR1H2; KAT2B; MECOM; CARF; ZNF350; MECP2; AES; ZNF43; JAK2; DLX4; TRIM22; FOXO3; ZNF768; RARG; ZNF117; PRDM2; ZNF354A; FOXN3; TRIM16; ATF3; MXI1; ZNF652; ZNF91; ZNF611; KLF5; GATA6; SNAI2; TFAP2A; TCF4; PBX1; BACH1; ZNF345; HMGN3; TCEB2; ZNF467; FOXO1; IRF6; SOX2; ZHX2; HMBOX1; ZNF264; LIN28A; PDLIM1; BRWD1; ZNF415; ZNF667; EHF; KLF13; ZNF75D; FOSL2; RXRA; HOXD1; SIM1; AR; VGLL1; ZSCAN18; TERF1; ID4; TLE2; ZNF711; ZFPM2; ZNF331; E2F5; EPAS1; SRY; BBX; MAF; SSBP3; TOX; HIVEP1; HLF; LMCD1; PKNOX2; MYCL; REL; CUX1; MNT; PEG3; SOX3; GATA2; ZNF423; FOXF1; BCL6; ID1; ZNF83; MEIS2; HOXD3; CREB3L2; ZMYND8; HOXB2; DLX5; TCF7L1; PAWR; BNC2; ISL1; ERBB2; NFE2L1; ID2; CERS4; NHLH2; TRPS1; CBFA2T3; AHR; KAT6B; MITF; TLE1; SOX17; BCL11A; ZNF512B; TRIM24; SOX11; CUX2; ESR1; TOB1; INSM1; TXNIP; RBFOX2; ETS2; ARNT2; POU2AF1; MTA1; HEY1; TWIST1; SCAND1; LITAF; BCL3; ZBTB16; MNDA; ERBB4; TFAP2C; SSBP2; NFATC4; TRIB3; ASCL1; VPS72; ZNF589; WT1; HOXB6; ZIC1; FOXO4; CREB1; MAFB
Down-regulation 95 CCNA2; FOSL1; HMGA2; EZH2; PSMC3IP; TFDP1; DNMT1; BRCA1; HMGA1; FOXM1; DRAP1; CDK2; EGR1; HMGB2; MYBL2; YEATS4; TBP; WHSC1; CHAF1B; MTF2; FHL2; ZNF143; RNF138; RBL1; CENPF; PA2G4; NPM1; TCERG1; WWTR1; RHOA; GMNN; DEK; ITGB3BP; RBBP4; BLM; HNRNPD; WDHD1; C1QBP; PTTG1; CBX5; HMGB1; ETV4; RAN; RBM14; BCLAF1; TRIM28; SSRP1; BRIP1; SF1; ATF1; BATF3; CCDC59; CHD7; EGR3; BAZ1A; TAF1A; NELFB; EED; BMI1; PPRC1; ATF5; SUV39H1; CBFB; NFIB; RAD21; ETS1; ASH2L; PSMC3; SMARCE1; TFAM; ELK3; HOXC10; MAFF; NPAT; RBBP8; ETV5; SAP30; ACTL6A; ZNF410; ARNTL; TSC22D2; CBX3; MSX1; NR2F1; MYBL1; NR2F2; PURA; SFPQ; DACH1; HMGB3; HOXC6; KLF2; PPARG; EGR2; LEF1