Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16155 Azd-8330 GSE70138 MCF10A Human 24h 0.12uM EID0005
Types Number Response transcription factors
Up-regulation 138 TSC22D3; ADRB2; NFKBIA; CALCOCO1; SOX4; VGLL4; CUX1; RFX5; PNRC1; NCOA3; TRIM16; HBP1; PBXIP1; ID2; ZNF44; ZMYM2; BTG1; ELF3; HDAC6; MXD4; NFIL3; ARID5B; EZH1; MZF1; BPTF; TRIM29; ZNF33B; PHF20; NR3C1; GATA3; BRCA1; CEBPD; REPIN1; BAZ2B; EP300; ZNF268; ZMYND8; HDAC9; NFE2L2; FOXO3; ZNF652; MXI1; AES; TAF7; DLX4; SOX12; BBX; TCF12; OSR2; CBX7; MEIS1; TP53; ZNF160; NCOA2; ELF1; KLF5; MNT; ZBTB16; TXNIP; ZNF587; NFE2L1; JUP; PDLIM1; TCEB2; LITAF; KAT6B; HMBOX1; MAF; LMCD1; SIAH2; AR; TLE1; HMGN3; PIR; ID3; FOSB; ZNF226; SSBP2; WNT4; ZKSCAN1; SP110; TRIM22; FOXO1; FOSL2; RNF141; TCF7L1; ZBTB38; CREB3L2; ZNF468; ZNF189; E2F5; CREBL2; PPARGC1A; IRF9; FOXN3; DDX17; ERBB2; TOX; SNAI2; ZIC1; KLF7; SMARCA2; ZNF91; SALL2; NCOA1; HEY1; ZNF415; SMARCA1; AHR; ESRRG; BCL6; MECOM; FOXA1; BCL3; MEOX2; PEG3; NCOR2; TOX3; STAT1; HTATIP2; MITF; ID1; KLF2; IRF6; HOXB6; CITED2; HOXB2; ATF3; CREG1; MAGED1; ETS2; CRYM; MYCN; EMX2; BASP1; CREB1; FOXO4; FOS
Down-regulation 89 CCNA2; FOSL1; HMGA2; FOXM1; DNMT1; MYBL2; EZH2; CDK2; MTF2; CHAF1B; TFDP1; CENPF; HMGA1; ETV4; KMT5A; GMNN; WHSC1; HMGB2; DRAP1; BAZ1B; TEAD4; ILF2; TFAM; WWTR1; PSMC3IP; WDHD1; C1QBP; RNF138; PA2G4; DEK; NOC2L; PRPF6; DR1; MYBBP1A; ETV1; NUP62; TRIM28; RBL1; HNRNPD; ETV5; E2F1; PTTG1; HIRA; CBFB; PSMC3; HHEX; BATF3; LZTS1; CAPN15; ARNTL2; TAF1A; NFIB; PPRC1; SOX9; SSRP1; BAZ1A; HMGB1; SATB2; ZNF232; MAFF; TTF1; AGO2; SAP30; NPM1; TGFB1; RAD21; TAF9B; RAN; PAX6; MYBL1; RBBP8; SMARCB1; SUV39H1; TFCP2; EGR3; IRF8; DLX2; NFE2L3; CALR; ZBED2; PBX3; NR2F1; EGR2; HOXC10; BHLHE41; ZNF22; WT1; NFATC4; SATB1