Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16154	Azd-8330	GSE70138	MCF10A	Human	24h	0.37uM	EID0005

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	TSC22D3; SOX4; PNRC1; NFKBIA; TRIM16; VGLL4; HBP1; TRIM29; BTG1; SRCAP; CALCOCO1; ADRB2; MXD4; HDAC9; ELF3; ARID5A; RFX5; AES; ZMIZ1; ZMYM2; ID2; NFIL3; ZNF195; PBXIP1; CUX1; ID3; TRIM22; ARID5B; IRF9; BPTF; HDAC6; JUP; NFE2L2; TCEB2; HTATIP2; NCOA2; IRF6; REPIN1; PDLIM1; TRAK1; RUNX1; REL; ERG; PPP1R13L; CSDC2; OSR2; ZNF768; ATF3; ELF4; ZSCAN31; HDAC5; SP110; SIAH2; WNT4; HMGN3; MLXIP; TCF7L1; NAB1; RNF10; MAF; SMARCD3; HIVEP1; PLAGL1; EPAS1; ERBB2; ID4; E2F5; LMCD1; ZNF43; FOSL2; KAT6B; TXNIP; ZNF165; TFDP2; GATA6; KLF2; ZNF117; MED13; ZHX2; NFE2L1; FOXO3; TLE1; WWC1; STAT6; MXI1; AEBP1; KDM5B; FOXN3; ZNF652; TFEC; FOXO1; ELF1; LITAF; SP140L; ZKSCAN1; ZBTB16; BCL6; TRPS1; EHF; SNAI2; MEIS1; TRIP6; TCF4; SMAD6; FOSB; CTBP2; BCL11A; NR1D2; MITF; ZEB2; IRF1; MECOM; ZNF91; ETS2; SOX17; CREG1; ZSCAN18; MNDA; MAFB; TOX; SSBP2; MYCN; MEIS2; PEG3; FOXO4
Down-regulation	100	CCNA2; FOSL1; CDK2; FOXM1; MYBL2; PSMC3IP; HMGA2; EZH2; TFDP1; RBL1; CENPF; DNMT1; BRCA1; CHAF1B; HMGB2; ETV1; CEBPD; WHSC1; DRAP1; HMGA1; YEATS4; ETV4; E2F1; MTF2; PA2G4; WDHD1; TCERG1; NUP62; TFAM; GMNN; SSRP1; BLM; DEK; HMGB1; TEAD4; TAF1A; TGIF2; TAF9B; BRIP1; NOC2L; BMI1; RNF138; BCLAF1; PTTG1; PPRC1; ETV5; EGR4; ETS1; TAF9; TDP2; XRCC6; HNRNPD; ILF2; NCOA6; NPM1; WWTR1; SATB2; TTF1; PRKDC; FOXE1; LHX2; CCDC59; ING2; RBBP8; CBFB; PAX6; RAN; BAZ1A; BRCA2; SAP30; E2F8; NKX3-1; RAD21; NR2F1; ZFHX4; MYBL1; ITGB3BP; NR2F6; YWHAB; FOXF2; BRD4; SOX9; NFIB; SUV39H1; ACTL6A; ZEB1; TBX3; HOXB7; HHEX; KLF6; HOXC10; EGR3; FOXF1; PPARG; MYT1L; DLX2; TGFB1; HOXC6; BHLHE41; SATB1