Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16153	Azd-8330	GSE70138	MCF10A	Human	24h	1.11uM	EID0005

Response Information :

Types	Number	Response transcription factors
Up-regulation	146	TSC22D3; MNAT1; TRIM16; SOX4; NFKBIA; BAZ2B; CALCOCO1; VGLL4; ARID5A; PBXIP1; SRCAP; ADRB2; SUPT7L; PNRC1; BPTF; ID2; HBP1; RFX7; NAB1; REPIN1; E2F5; ZMYM2; ARID5B; HDAC6; RING1; TRIM29; ZNF268; BTG1; TP63; SIAH2; ZKSCAN4; DLX4; EP300; ING4; NFE2L1; NR2C1; IRF9; NFE2L2; NR3C1; HDAC5; RFX5; TCF12; ZNF34; CUX1; OSR2; HDAC9; PHF20; MXD4; SIRT2; MECP2; NFIL3; CBFA2T3; HMGN3; PDLIM1; ZNF84; ZSCAN31; ZFHX3; WNT4; ZHX2; TFDP2; HIVEP2; ZBTB11; AR; ZNF160; STAT6; ZNF665; ARHGAP35; CBX7; PHIP; BBX; RNF10; CREBL2; REL; ATF7IP; ELF3; SERTAD2; ZNF85; LITAF; CDYL; ARNT; PRDM2; RLF; JUP; GTF3A; HMBOX1; MBD4; MDM2; MECOM; HIVEP1; DBP; ELF1; FOXO3; SALL2; ID3; ELF4; TRIM22; ESR1; SP110; FOSL2; PAWR; MYCL; RBL2; GRHL2; SREBF1; NCOA2; IRF6; AHR; IRF7; CITED2; MEOX2; TLE1; FOSB; TCF4; ERBB2; ZKSCAN1; TOX; ZNF652; TCF7L1; ZFPM2; BCL6; MAF; ZNF512B; GATA6; LMCD1; ATF3; ZBTB1; NKX2-1; MITF; RSF1; BCL3; HTATIP2; ZBTB20; NCOR2; ASCL1; MEIS1; PIR; ID1; ZNF91; ZSCAN18; POU2AF1; SSBP2; BASP1; ARNT2; EMX2; FOXO4; FOS
Down-regulation	111	CCNA2; FOSL1; FOXM1; EZH2; DNMT1; MYBL2; TFDP1; PSMC3IP; EGR1; ETV1; CENPF; CHAF1B; HMGB2; HMGA2; BRCA1; TDP2; ETV4; E2F1; CDK2; RBL1; GMNN; BLM; DRAP1; PA2G4; TBL1X; DNAJC2; TAF9; CAPN15; EGR4; C1QBP; BAZ1B; RUVBL1; SAFB2; TCERG1; PPRC1; PTTG1; TFAM; CBFB; HMGA1; RNF138; KMT5A; YEATS4; SAP30; WHSC1; WDHD1; ETV5; SSRP1; MXD1; CARM1; POLR3C; NPM1; CBX5; GATAD2A; EGR3; GATA4; TCF21; PAX6; TEAD4; NELFB; HOXC10; HOXD10; NR2F1; SIM2; ING1; LHX2; SATB2; BCLAF1; MAFF; CCNE1; WWTR1; MYBL1; ILF2; RB1; EGR2; SUV39H1; TGFB1; HES1; BRCA2; NPAS2; BATF3; NR2F6; BMI1; HNRNPD; SOX9; ZEB1; HOXD11; PSMC3; HOXB7; CEBPZ; FOXG1; NANOG; BHLHE40; HMGB1; ZBTB18; NFIB; CITED1; PITX1; NKX2-2; MYT1L; PURA; HOXC6; IFI16; PBX3; HOXB6; FOXF1; SOX11; PEG3; BHLHE41; WT1; KDM5D; SATB1