Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16152 Azd-8330 GSE70138 MCF10A Human 24h 3.33uM EID0005
Types Number Response transcription factors
Up-regulation 376 TSC22D3; ARID5B; PNRC1; CALCOCO1; SOX2; HBP1; ZNF268; ZNF688; BTG1; ZNF304; IRF9; GLI2; ZNF667; CBX7; SOX4; TRIM29; ZNF350; MZF1; ZFHX3; CREB3L2; ZNF195; ZNF33B; RFX5; ZNF224; CUX1; PBXIP1; ZIC4; ZNF14; SRCAP; ZNF669; L3MBTL1; SIM1; ZNF529; ZNF665; NCOA3; ZNF586; CDIP1; MEIS1; PRDM2; MYF5; TBX6; ZNF135; FHL5; TLX2; ZFP2; VGLL4; ZNF337; SCAI; CSDC2; CREBL2; HDAC9; ZNF112; ZNF136; PRDM16; MEF2C; ZNF506; NR5A1; FOXN2; FOXL1; ATF3; ZKSCAN4; CARF; HDAC5; ZBTB16; ZNF768; ZNF484; ZNF117; HNF4G; SP4; SOX21; ZSCAN9; TBX5; ZNF254; RFX3; ZNF91; BPTF; ZNF43; BACH1; TXNIP; ZNF223; ZNF442; BCL6; ING4; ZNF222; AR; TRPS1; ISL1; PPARA; SIX3; ZBTB44; ZNF652; DYRK1B; ZNF133; ZNF248; ZNF671; OSR2; TFEC; NR1H2; CIITA; ZNF345; KAT2B; ZNF257; ZNF444; TBX4; ATOH1; ATF2; SUPT7L; ZNF235; PRDM9; ZNF155; NCOA2; TBX19; ZNF573; PEG3; ZNF44; ZNF34; ESR1; CIR1; ZNF606; AFF2; ZNF132; HMBOX1; PKNOX2; NFAT5; ZNF419; ZNF225; TBX10; WNT4; JUP; ZNF701; ZNF264; ZNF253; ZNF571; ZNF611; YEATS2; ZNF391; ZNF174; SOX5; MDM4; HOXB3; KLF5; SOX17; REPIN1; GATA6; FOXB1; ZNF85; POU6F2; ZKSCAN8; SIX5; SOX12; MAK; ZBTB3; ZNF814; ZMIZ1; ZNF471; MXD4; MED25; TSHZ2; LHX3; ZNF287; ZNF12; SKI; MYCL; NFIX; CEBPD; VGLL1; ZKSCAN1; ZNF362; ARID5A; TEF; ZNF467; ETV2; ONECUT1; HIF3A; TAF1C; ZNF675; SALL2; GSC2; MEOX1; TCF7L2; ZNF536; EPAS1; BAZ2A; ZBTB17; MYT1; KLF13; ZNF426; TCEA2; BCL11A; JUND; POU1F1; EZH1; TULP1; ZNF81; REL; ZNF154; ZNF623; ZNF500; HOXB1; MDM2; PEX14; GATA2; MEIS2; SOX3; HSF1; ZNF492; TP63; ZNF7; SPI1; ZNF430; THRB; TCF21; FEZF2; ZNF80; ZNF415; ZNF780B; ZNF124; ZNF674; HESX1; CREB5; MKL1; E2F5; POU2F1; AES; CBFA2T3; ZNF165; ZNF354A; ZNF493; ZNF140; LMCD1; ZNF695; ZNF682; ZNF580; LIN28A; ZFP30; SMARCC2; NEUROG2; VENTX; ZNF75D; TLX3; EBF2; ZHX2; ZNF334; SP110; SCRT1; ZSCAN31; SNAI2; RORC; SRY; ZNF10; MEN1; FOXO3; ZNF141; SMARCD3; AEBP1; NAB2; HSF4; SOX18; ZKSCAN7; PRDM1; ARHGAP35; HIVEP1; E2F2; SHOX2; NR0B2; PRDM12; SP140L; ZNF175; TRIM22; SKIL; IRF6; DLX5; FOXN3; RXRG; ZSCAN16; TFDP2; TRIM16; TEAD3; ZNF358; NR5A2; CBX4; SSBP3; FOXJ1; SP100; TP73; ZNF593; HLX; ELF4; ZNF468; TCF4; ZFPM2; ELF3; MXI1; JUN; HLF; POU2F2; ID4; TCF7L1; EHMT2; ERBB4; MYNN; MED17; NKX3-1; ZNF93; TCEB2; CERS4; ELF5; NEUROD1; INSM1; PAWR; TSC22D1; ZNF544; POU2AF1; DDIT3; MYCN; CUX2; FOSL2; TRIM24; ZBTB20; ZNF83; MITF; CD3D; ZSCAN18; TRIB3; ZNF331; LITAF; ACTL6B; FOXO1; NR1H3; PDLIM1; NR1H4; HTATIP2; RSF1; ZNF711; ZNF423; TLE1; IKZF1; FOSB; AHR; INSR; EHF; ZNF512B; DLX2; FOXF2; TOX; TULP3; PBX1; BNC2; FOXC1; EN1; HOXB2; HIC2; NANOG; BACH2; MNDA; ARNT2; TFAP2C; IRF1; HEY1; VPS72; PLAGL1; BCL3; MYRF; SSX1; SPDEF; TOX3; ASCL1; PBX3; WT1; NFATC4; MAFB; ZIC1; NFATC3; MAF; EMX2; FOS
Down-regulation 98 CCNA2; FOSL1; HMGA2; EZH2; TFDP1; DRAP1; HOXA5; PSMC3IP; TCERG1; NUP62; PARP1; WHSC1; HMGB2; FOXM1; RBBP4; MYBL2; BRCA1; MYC; CTR9; FHL2; ATF4; XRCC6; HMGB1; CHAF1B; CENPF; RUVBL1; SMARCA5; HMGA1; CBFB; BCLAF1; BMI1; GMNN; MYCBP; BAZ1A; RBL1; PMF1; SSRP1; HNRNPD; CBX5; PRKDC; MLX; DNAJC2; RNF4; PMS1; UBE2I; HDAC1; ETV4; ELK3; TAF9; SMARCA2; YWHAB; PA2G4; HOXA1; TAF10; BHLHE40; SMAD3; BASP1; RBM39; HOXB7; NELFB; RBM14; EED; ILF2; RAN; DEK; NCOA6; BLM; HLTF; SUB1; SUV39H1; EGR3; RREB1; MNAT1; ITGB3BP; HSBP1; EDF1; NR2F1; NPM1; ING3; ING2; PTTG1; ABL1; TRIP6; SFPQ; XBP1; KDM5D; MED1; PSIP1; PSMC3; JARID2; TOB1; STAT3; NR4A2; IRX5; HOXC10; MYB; SATB2; TCFL5