Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16151 Azd-8330 GSE70138 MCF10A Human 24h 10uM EID0005
Types Number Response transcription factors
Up-regulation 130 TSC22D3; NFKBIA; RFX5; GLI2; CALCOCO1; PNRC1; IRF9; VGLL4; ZSCAN31; NCOA3; GATA3; CREBL2; HBP1; SP110; MXD4; SOX12; NAB1; PBXIP1; ID2; MYBL2; ELF3; ARID5B; NFIL3; ZMYM2; TRIM29; WNT4; TRIM22; HDAC9; NFE2L2; IRF7; ZNF33B; SRCAP; CEBPD; TRIM16; FOXO1; BPTF; OSR2; GATA6; SOX4; FOSB; PDLIM1; CSDC2; AES; ZNF467; NCOA2; TBX1; MED13; ID3; ZBTB38; TRPS1; CERS6; ATF3; PIR; TRIM24; ZFHX3; HMGN3; ZNF606; NFE2L1; HLF; PHF20; GRHL2; HIVEP1; REPIN1; MYCN; MBD2; MAF; JUN; JUP; MYCL; BNC2; HOXB13; PLAGL1; TERF1; RBPMS; SIAH2; FOXO3; TLE1; MEIS1; WWC1; CUX1; BAZ2B; TOX3; SMAD6; ISL1; JUNB; CUX2; RLF; COPS2; KLF5; NFAT5; MEOX2; HTATIP2; PAWR; MYRF; FOXN3; ETS2; HDAC1; JUND; ZNF217; ZKSCAN1; KAT2B; PBX1; SP3; MXI1; PITX1; ZBTB1; KDM5B; ESR1; IRF1; MECOM; TFAP2C; SALL1; DACH1; HIPK1; TOB1; AHR; MITF; ARID4B; TXNIP; CREG1; BCL3; POU2AF1; KLF10; SSBP2; BASP1; TCF4; FOXG1; MAFB; ID1; KDM5D
Down-regulation 69 CCNA2; FOSL1; EZH2; DNMT1; HMGA2; FOXM1; BRCA1; CDK2; ETV1; HMGB2; TFDP1; PSMC3IP; WHSC1; TCERG1; GMNN; CENPF; CHAF1B; ILF2; MED27; HMGA1; RBBP8; TAF1A; DRAP1; DEK; CBX5; NUP62; C1QBP; XRCC6; RBL1; SSRP1; GATAD2A; MYBL1; HMGB1; TDP2; RUVBL2; CEBPG; PA2G4; ETS1; PTTG1; BATF3; RNF138; YWHAB; HIRA; RBPJ; NFKB1; WWTR1; PMS1; CCDC59; SAP30; CHD7; ING3; HNRNPD; ZEB1; VDR; NR2F6; CCNC; SUV39H1; RAD21; SMARCB1; DLX2; IRX5; BCLAF1; CREM; PBX3; PURA; NR4A2; SATB2; PPARG; SATB1