Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16146 Ldn-193189 GSE70138 MCF10A Human 24h 10uM EID0005
Types Number Response transcription factors
Up-regulation 298 TSC22D3; NFKBIA; CEBPD; HBP1; NFKB2; CALCOCO1; IRF9; ZBTB48; IRF7; TSG101; EP300; AR; PRDM2; CSDC2; NR1H2; HDAC5; NCOA3; ZNF611; MAFG; MECP2; UBE2B; ZNF160; HINFP; ATF3; ZNF131; NR4A3; STAT2; TBX3; TBX6; PNRC1; ZBTB43; SRCAP; ONECUT2; TULP2; NCOA2; ZNF701; GATA6; NR5A1; RFX1; ZNF536; BANP; BARX1; EZH1; JUND; REL; ZNF550; JUNB; RFX3; ASCL3; ESRRB; HOXB1; CIR1; PRDM9; IKZF3; BPTF; NR4A1; CBFA2T2; NOCT; NACA2; IRF1; ZNF24; ZNF154; SIX5; MZF1; ZBTB7C; MED13; DDIT3; HOXB13; BTG1; SOX1; ZNF224; ARID5B; SHOX2; ESR2; AFF2; HIVEP1; GATA3; ZNF136; MXI1; MSC; LHX3; FOXD3; ZBTB17; TEF; JUP; ATF4; NFIC; NFE2L2; ZHX2; ZFHX3; SUPT7L; POU6F2; THRB; OSR2; CRX; ZNF117; GBX2; SOX2; CBX7; MEF2C; DYRK1B; BACH1; POU2F3; MDM4; ZNF394; ZNF350; CBX4; ZNF268; ZNF665; CHD1; HMBOX1; NR4A2; PHOX2A; SIN3B; GBX1; HIF3A; NFIX; ZNF331; ZNF440; PAXBP1; WNT4; PHIP; RSF1; PRDM12; PLAG1; TWIST1; ATOH1; PAX9; CBFA2T3; ARID4B; FEZF2; CDIP1; POU4F2; ING4; ZNF500; ZNF91; MLLT1; MYF5; KLF13; FOXO3; PKNOX2; SOHLH2; PEX14; RXRG; CERS4; ZNF675; TERF2; NKX3-2; ZNF257; BCL6; L3MBTL1; BNC2; CNOT2; SAFB; TULP1; VENTX; DLX4; TLX3; ZNF667; ZNF225; NEUROG2; BRDT; ZNF682; NKX2-1; ZNF10; STAT1; MAFF; GMEB2; ZBTB44; POU4F3; HOXD1; HOXD3; SUPT4H1; CUX1; SRY; ZBTB7A; ZNF75D; FOXA1; INSR; MYCL; TAF7; ZNF345; SCAI; E2F2; CREB5; MED17; PIAS4; DBP; HIVEP2; ZNF721; FOSB; ST18; TCF7; CREBL2; BHLHE41; ZFHX4; SOX18; DDX17; ERBB4; TBX1; SOX3; RLF; SIX3; GLI2; NAB2; LDB1; GATA2; MEIS2; SP140L; ZKSCAN1; CAMTA1; GRHL2; SPEN; ZNF141; ZNF165; RNF10; ELF4; EN2; KAT2B; PAWR; PITX2; XBP1; CREM; ZNF652; MNDA; HLX; NEUROD1; ZBTB16; CUX2; CITED2; TRPS1; RELB; EYA1; E2F5; FOXF2; ZIC1; TCF21; HDAC9; RORA; ZNF264; TRIM29; HES1; HIC2; IRF8; ISL1; ZNF430; SMARCA1; TRIM22; PEG3; TRIM16; ZFPM2; ZNF93; TCEA2; ASCL1; FOSL2; TLE1; SOX10; KLF4; AEBP1; WT1; TCF4; INSM1; TOB1; CD3D; ZNF423; BCL11A; ZSCAN18; KLF6; HHEX; NFATC4; HIPK1; DLX5; MITF; POU2AF1; FOXF1; SSX1; RUNX3; SIX2; FLI1; BHLHE40; HTATIP2; FOS; SOX11; ZEB2; MYRF; BASP1; CRYM; ARNT2; BCL3; ZNF589; TXNIP; TFAP2C; SPDEF; MAF; NFATC3; PBX3; FOXO4; KDM5D
Down-regulation 86 CCNA2; ADRB2; FHL2; MYCBP; TFDP1; PARP1; FOXM1; EZH2; HOXA5; WWTR1; CENPF; PDLIM1; DNMT1; CHAF1B; HMGA1; MYBL2; GMNN; ITGB3BP; BRCA1; NRIP1; TAF9B; DEK; ELK3; MKL2; PA2G4; HMGA2; ETV1; YEATS4; CBX5; SMARCC1; SMARCA2; HMGB1; HOXB7; ING2; NFIB; CARHSP1; EED; ZBTB38; ZFP64; SMARCD2; NR2F2; WHSC1; HOXA1; CBFB; RBBP4; HNRNPD; TRIM28; PTTG1; NPM1; ID3; NELFB; PSIP1; GTF3A; HMGB2; RBBP7; JARID2; ZNF32; BMI1; ZBED4; DNAJC1; PIAS3; BLM; PMS1; CBX3; NCOA6; C1QBP; STAT6; RNF141; SFPQ; MTDH; SMAD1; FOXC1; FOXJ3; SUV39H1; ETV5; SUB1; TRIM32; ERBB2; HMGB3; ID1; ZNF22; TCFL5; IKBKAP; HOXB6; HOXC6; HMG20B