Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16144 Cgp-60474 GSE70138 MCF10A Human 24h 0.12uM EID0005
Types Number Response transcription factors
Up-regulation 676 ZNF701; ZNF304; NFKBIB; ZNF136; ZNF586; CDIP1; ZNF611; ZNF665; RFX1; ZNF91; ZNF44; PRDM14; ZNF117; ARID5B; TSC22D3; EP300; TLE2; ZNF350; TAF4B; NEUROD1; NR1H2; POU6F1; LIN28A; ZNF550; ZNF419; ERBB4; ZBTB3; ZNF667; ZNF331; TULP2; RFX3; OVOL1; ASCL3; ZIC3; NR6A1; CBX2; CBFA2T3; PRDM2; CHD2; ZNF671; RING1; EMX1; FOXH1; ING4; HINFP; ZNF549; ZNF329; HOXB8; ZNF778; EZH1; SHOX; THRB; ZNF79; ZNF571; CSDC2; ZNF816; ZKSCAN8; ZNF43; CBFA2T2; MECP2; ZNF529; ZNF573; ZNF257; ZNF180; SOX18; ZNF440; POU6F2; SOX21; PRDM5; ZNF492; HBP1; ZNF391; PAX6; ZNF442; IRF9; ZNF814; ZNF695; ZNF211; SOX5; ZNF682; LHX3; ZNF3; IKZF3; ZBTB44; SOX2; ZNF268; ZNF221; FOXE3; FEZF2; ZNF154; ZNF749; ZSCAN32; NEUROG2; NRL; ZNF223; HES2; SP4; ZXDC; PHIP; NEUROG3; E4F1; PAX2; ZNF669; ZIC4; PRDM10; ONECUT1; ZNF235; ZNF688; ZNF132; E2F2; SCAI; VENTX; HDAC5; ZNF394; ZNF500; ZNF507; PEX14; ZNF264; NHLH1; MAK; ZNF85; GRIP1; TAF11; TBX5; ZBTB43; PRDM9; FOXD3; SCRT1; ZNF135; SALL2; ZNF83; NKX3-2; PAX7; ZNF160; ZNF345; GCM2; POU3F3; SNAPC4; ZNF430; L3MBTL1; ZNF273; ZNF174; SOX3; PAX4; ZNF254; ZNF134; ZNF141; ESRRB; SOX14; SSX7; MAPK8IP1; ALX4; TWIST1; SIX3; CALCOCO1; LHX1; GFI1B; ZNF208; MYCL; NEUROD2; DOT1L; ZNF460; NR5A1; ZNF426; HNF4G; AR; POU2F3; ZFP2; ZNF225; ZNF674; ZNF407; ONECUT2; ZNF222; CUX2; DLX4; ZKSCAN4; PRDM16; ARID3B; AFF2; GRHL2; ZNF343; ZNF214; ASCL2; VHL; TEF; TLX1; ZNF80; ZNF780B; ZNF157; ZNF471; SOHLH2; ZNF613; CBX7; ZNF81; ZNF75D; ZNF274; ZNF334; TAF6L; ZNF14; RARG; RARB; CUX1; NHLH2; NFKB2; ZNF480; PAX1; ZNF711; ZNF142; KLF13; ZNF506; GCM1; GSC2; ZNF467; NANOG; WNT4; EZH2; NOCT; HESX1; PAX3; ZNF764; ZNF675; ZNF721; ZNF606; TBL1Y; POU1F1; TGIF2; DACH1; NEUROD4; ZNF510; CAMTA2; ZNF184; ZNF324; TBR1; ZNF34; HNF1B; ZNF362; POU4F2; CDX4; ZBTB39; ZBTB48; HOXB1; TBX4; BRDT; ZNF239; ZNF544; TDP2; ZXDB; MEF2C; AIRE; ZFY; ZNF623; THAP9; BNC2; DCC; SRY; LMX1B; SP2; PPARA; TLX3; TAF1C; ZSCAN2; ATOH1; HOXD3; WHSC1L1; DMRT1; BARX1; ZNF562; FUBP1; CBX8; POU3F4; CIITA; SOX1; HOXD1; PIAS4; GLI2; FOXI1; SUPT7L; ZNF202; TFDP2; ETV3; TFDP3; ZNF423; ZNF551; SCMH1; ZNF287; ZNF770; IFNB1; GATA1; CBX4; SUPT4H1; CCNH; ZBTB17; TFEC; BRWD1; MAML3; GATA6; GMEB2; FOXN1; OSR2; SSBP3; ZNF253; ESR1; ZIM2; EPAS1; HOXD12; ZNF41; TXNIP; ZNF493; ZKSCAN1; RORB; HIC1; PKNOX2; DLX2; DAXX; TBX6; RFX2; ZNF200; CIR1; ZNF24; ZNF16; HIRA; ZFPM2; ZNF195; TCF7; FOXD2; ZFP69B; KLF8; MDM2; PROP1; RBPJL; SIN3B; MED31; ZNF250; POU4F3; NKX2-5; MLLT1; ZNF165; NCOA3; MYEF2; ZNF12; ZNF234; GON4L; ALX3; INSR; ZNF219; EN2; MSX2; CRX; ZNF415; ID4; FOXP3; PRDM13; TERF1; IL16; ZSCAN31; TRIM24; ST18; TCEA2; PRDM1; SOX17; ZNF212; TEAD3; PNRC1; HEY2; GBX2; ZNF140; ZNF484; PHF1; ZNF93; TFAP2A; DYRK1B; ZNF155; ZNF107; ZNF8; NAB2; HDAC9; NKX2-1; ZNF552; ZSCAN16; ZHX2; E2F3; ZNF652; TCF21; MXD4; MED12; ZNF215; NR2E1; SIX6; KLF15; ZNF232; ZKSCAN7; ZNF263; ELF4; RXRG; LBX1; UTF1; FOXB1; ZBTB7C; IRF8; HOXC11; NEUROG1; EYA3; SOX30; ZBTB20; MED25; AFF3; HSF1; DLX6; IKZF2; ZNF10; TP73; PRRX1; TAF7L; NFRKB; ZSCAN9; RORA; ZNF536; VGLL1; ZNF557; FOXE1; ZNF444; ZNF813; HOXD13; SNAI1; MDM4; GBX1; ERF; CAMTA1; HIC2; NFE2; ZNF33B; HNF4A; E2F5; MXD1; FOXJ1; HLX; CD3D; ETV2; BNC1; ATF6B; ZNF835; IKZF1; DLX5; LMO1; PBXIP1; NEUROD6; TUB; E2F6; HABP4; ATF3; MYT1; NR0B2; CERS4; MNDA; ZNF74; TRIM22; SPI1; ZNF124; GFI1; ZFP37; MEIS2; NFE2L3; MYF5; NR1I3; SKIL; SKI; IRF7; RARA; CARF; TFEB; MED17; VAX2; ACTL6B; E2F1; ATF2; ZNF286A; KLF3; ID2; NACA2; BCL11A; TULP1; ZNF226; HIF3A; TGFB1I1; TULP3; ZBTB7B; HOXD9; NFE2L2; BARX2; ZNF177; ZNF7; ZFHX3; PHF20; ZSCAN18; RSF1; MECOM; HOXA2; TRPS1; FOXN3; TOX4; POU2F1; ZNF512B; HNF1A; ZBTB6; EHMT1; THRA; EVX1; BHLHE41; LZTS1; CBL; TBX1; WT1; ANKRD1; ZNF654; ARID3A; KDM4A; ZNF468; ETV7; YBX2; PRDM12; REL; ZNF112; HSF4; ZNF148; GTF2I; PPP1R13L; STAT2; HEYL; SUPT3H; ZNF528; OVOL2; ZFP30; ZNF354A; PPARD; ZNF432; NFYC; PDX1; HOXC13; ELK4; CREBL2; SETDB1; ZBED2; BACH1; TBX19; MEN1; HOXC5; NR1H4; MED14; SSX1; ARL2BP; CEBPE; ZNF587; CIZ1; INSM1; HOXB13; AEBP1; PEG3; NR5A2; NR4A3; ZNF224; SP140; HOXD11; HOXA3; MTF2; PCGF3; POU2AF1; KLF11; HOXB5; OLIG2; IRF5; MYRF; CEBPD; MEOX2; PAWR; LYL1; FOXG1; LHX2; HHEX; NFIC; GATA4; SOX11; LMCD1; PGR; ZNF266; IRF6; DBP; HIPK2; EGR4; REPIN1; STAT4; TAF5L; SMAD7; TBX2; ZBED1; TGS1; NR0B1; CREM; CDK9; SOX13; NCOA2; PBX3; EN1; RBPMS; MYNN; FOXL2; TGFB1; JAK2; AES; PLAG1; KDM5C; SALL1; ING3; GTF2F1; NR4A2; PIAS1; BACH2; CNOT2; TOX; SPDEF; BANP; ESRRG; PROX1; NKX2-2; KMT2A; RAD21; SMAD1; FOXO1; SMARCD3; TBX3; HIPK1; NR3C2; TCF7L1; FOXA2; ZNF217; BRD4; SMARCA1; CNOT3; NFATC3; MYBL1; SHOX2; CCNE1; CREB5; HLF; TAL1; TRIB3; CITED1; NR4A1; CHD8; ARNT2; TFAP2C; FOXF1; ZNF589; TCF4; BTG1; FOSL2; NFATC4; POU4F1; MXI1; TOB1; JUP; SMAD6; THAP11; PBX1; STAT3; RUNX3; LEF1; FLI1; VPS72; ZBTB16; KLF10; SATB1; CRYM; SOX9; EGR2; CREB1; MAFB
Down-regulation 151 MYC; CCNA2; ADRB2; TFDP1; FHL2; FOSL1; GTF2A2; RBBP4; HDAC2; ATF6; SMARCC1; TCERG1; HOXA5; ATF1; TP53; BMI1; ORC2; NFIL3; PARP1; BAZ1A; RUVBL2; NRIP1; CBFB; HSBP1; ZBTB38; MYCBP; EED; ENO1; HMGA2; NUP62; BRD3; HMGB1; MBD2; YBX1; SMARCA2; BLM; TAF10; RBBP7; BCLAF1; ASH2L; PA2G4; C1QBP; RAN; HNRNPD; SMAD3; CTR9; RBM14; SF1; RHOA; PTTG1; ATF5; TLE1; HOXC6; PBRM1; BRCA1; HOXB7; SFPQ; HLTF; KLF5; SMARCE1; NCOA1; CENPF; NPM1; FOXD1; SMAD2; MAGED1; CNOT1; TEAD1; SSRP1; EGR1; HMGB3; NFKB1; UBP1; RUNX1; WHSC1; TMF1; ATF4; GCFC2; MAZ; UBE2I; JARID2; PPARGC1A; NEDD8; PRKDC; BASP1; ZMYM2; ELK1; TRIM28; ETS2; MNAT1; XRCC6; CBX5; SMARCD2; PURA; NCOR2; PHF2; NCOA4; JUNB; SREBF1; CTNNB1; NCOA6; STAT6; ITGB3BP; ARNTL2; AATF; RBM39; TAF9; HOXC10; SMARCA5; TRIP6; ZNF146; BHLHE40; PMS1; GTF3A; TCF12; RNF14; NR2F2; AFF1; HES1; PPRC1; DEK; ALX1; YWHAB; ZNF532; TFAM; HDGF; TBL1XR1; GATAD2A; MED1; APEX1; MED24; CREG1; XBP1; HMGA1; ABL1; ELF1; DDX17; ARNTL; SPEN; SUB1; CALR; ARID4B; ERBB2; EGR3; IKBKAP; PUF60; HTATIP2; STAT5B; ELK3; PITX1; ID1