Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16143 Cgp-60474 GSE70138 MCF10A Human 24h 0.37uM EID0005
Types Number Response transcription factors
Up-regulation 760 ZNF586; MEF2C; EP300; ZNF331; RFX1; NR6A1; E2F2; ZNF350; RFX3; ZBTB44; SOX17; ERBB4; AR; ZNF701; EGR1; TBX6; ZFPM2; REL; SCAI; ZNF667; ARID5B; SOX18; ZNF154; ZFP2; GLI2; ZNF43; ZNF85; PRDM9; ZNF536; ZNF117; NEUROD6; ZNF257; THRB; FEZF2; ZNF136; FOXH1; ZNF671; HOXC8; RBPJL; ZNF682; ZNF180; NR1H2; EMX1; LHX3; ZNF550; ZSCAN2; ZNF695; HOXD3; ZNF442; ZNF814; ASCL3; TSHZ2; SALL2; IRF9; NRL; SOHLH2; SSX3; POU6F1; PRDM14; ZNF688; CBX2; ZNF304; SHOX; E4F1; NEUROG1; NEUROD2; HNF4G; NR5A2; LMX1B; CHD2; IKZF3; ZNF816; CRX; PRDM10; NEUROD4; ZNF440; NEUROG3; ZIC4; ZNF264; FOXE3; NR4A3; ZNF268; LZTR1; KAT2B; CDIP1; CBFA2T3; ZNF556; L3MBTL1; CARF; SP4; ZNF573; ZNF507; EZH1; ETV3; POU6F2; HES2; HBP1; DCC; ZNF254; AFF2; TBR1; ZNF500; ZNF345; BRWD1; ZNF221; SSX7; ZNF224; VENTX; GSC2; ZNF506; TGIF2; POU2F3; ZNF91; ZBTB48; HAND1; SOX5; TBX5; ZNF611; HOXD12; ALX4; HINFP; NEUROG2; PRDM16; HOXB1; GRIP1; CBX7; ZNF613; CCNH; WHSC1L1; NR2E1; SKI; ZBTB43; ZBTB3; ATOH1; TULP2; ZNF571; PAX3; MAML3; TFDP3; CAMTA2; ALX3; ZNF549; ST18; PAX4; GCM2; ZNF492; FOXD3; ZNF770; MECP2; ID4; ZNF235; SUPT7L; ZNF749; RING1; NR5A1; ZNF362; PRDM5; ZNF471; ESR1; SRY; SOX3; ZNF75D; TAF1C; ZNF529; ZKSCAN3; ZNF467; LIN28A; ZNF669; ZNF391; SOX21; ESRRB; POU1F1; ZNF493; GRHL2; BNC2; ZNF484; POU3F3; ZNF223; ZNF132; ZNF80; ZNF415; NEUROD1; TLX2; ZIC3; ZNF81; FHL5; CDX4; ESR2; SOX14; NHLH1; PROP1; ZNF225; ZNF135; HIC1; ZNF407; HHEX; HIF3A; TBL1Y; ZNF665; GFI1B; RXRG; ING4; ZNF674; ZFHX2; PRDM2; ZNF157; CALCOCO1; ZNF287; SPI1; TWIST1; NR1I3; TFAP2B; ZNF44; SCRT1; HOXA6; ZNF93; ZNF33B; NKX6-1; ZNF780B; ZNF606; GBX1; TEF; ZNF239; EYA3; TBX4; ZKSCAN8; SOX1; HNF4A; ZNF41; HDAC9; FOXP3; VHL; POU3F4; ZNF214; PBX2; ZNF273; ZNF175; CIITA; ZNF14; TBX10; CERS4; ETV2; ZSCAN9; PAX7; ZNF562; THAP9; FOXB1; RORB; HOXB8; ZBED2; ASCL2; NFKB2; GATA2; ARID3B; BARX1; RFX2; SRCAP; IKZF2; ZNF112; ARID5A; PDX1; ZNF711; ZKSCAN4; FOXL1; MED12; TAF6L; ZNF423; TCF4; DOT1L; ZNF208; ZNF195; MAPK8IP1; CBX4; OVOL1; PRDM1; GLI1; ZNF623; KLF13; MXD4; GCM1; CREB3L2; BCL11A; ZNF234; MSX2; SSBP3; ONECUT2; MDM4; ZNF155; TLX1; DLX5; CUX2; SIX6; HOXA3; ZXDB; NKX3-2; TP73; CBFA2T2; PKNOX2; LBX1; MEIS1; TULP1; ZNF8; HOXD9; FOXI1; WNT4; ZSCAN32; LHX6; ZNF142; TCF21; BRDT; PAX1; ZNF10; HABP4; MLLT1; FOXF2; HDAC5; ZNF343; HIC2; HESX1; VGLL1; GBX2; MEIS2; MED31; ZNF394; HEYL; ZXDC; ZNF334; PHF1; ZNF639; MAFK; TUB; THRA; ZNF675; OVOL2; STAT2; SUPT3H; ZNF764; SOX2; KLF8; LHX1; DLX4; POU4F2; ZNF141; ZNF654; MYEF2; AFF3; SIX5; ZNF253; ZNF250; CUX1; ZBTB7B; ONECUT1; ZNF79; RUNX2; ZNF778; RSF1; MYF5; HNF1B; NR3C2; MAK; POU4F3; ZNF768; BACH1; SUMO1; IFNB1; DLX6; ZNF215; CIR1; SHOX2; NKX2-5; NFIX; NPAS1; PAX2; ASH1L; MYCL; ZNF174; GATA6; MEOX1; HAND2; EHMT1; FOXD2; HSF4; MECOM; ZFHX3; MXD3; ZNF460; TBX1; NACA2; NHLH2; HOXB5; HOXD1; EVX1; TBX19; CEBPE; ZNF184; HOXD13; ZNF34; TFEC; E2F4; PRDM13; NR4A1; NR4A2; ZNF134; LMCD1; ZEB1; LMO1; DLX2; RARG; FOXE1; HIVEP1; THAP7; PHOX2A; ZNF140; ZNF696; ZNF329; PRRX1; ZFY; PHOX2B; ZNF197; ZNF480; BPTF; ZBTB20; ZNF222; ZSCAN18; PLAG1; TCEA2; GATA3; ZNF131; MED25; VSX1; PRDM12; NAB2; CSDC2; ZFP69B; CREM; ZNF813; PAX6; ZNF668; GMEB1; HMGXB3; TLE2; FOXF1; CCNE1; ATF7; KLF15; ZBTB17; FOXN1; IKZF4; ZSCAN31; ZIM2; NOCT; TONSL; ZNF444; SOX30; ZBTB7C; TAF7L; LHX5; HOXB13; IRF8; CIC; THAP3; BNC1; ZNF419; RAX; SUV39H2; SNAPC4; ZNF557; ZNF133; EBF2; HMBOX1; SKIL; POU2F2; TULP3; TEAD3; ZFP30; ZNF551; HLX; ZSCAN16; WT1; ZNF124; SSX1; CREB5; HOXC5; ZNF248; MYT1; ATF3; LHX2; HOXA2; HNF1A; IRF6; NKX2-8; KDM5C; MZF1; JAK2; FOXN3; APBB1; PAX8; KMT2D; ZNF165; SNAI1; IRF7; POU2F1; MKL1; TFAP2A; BHLHE41; TRIB3; TAF1; PBXIP1; BAZ2A; RFXAP; ELK4; DMRT1; ATF2; CRTC1; CREBL2; EN2; PEX14; MXI1; SIM1; PIAS4; ZNF468; RORC; PPARA; NR0B2; TAF4B; MEOX2; ZNF710; AIRE; ARHGAP35; YBX2; CBX8; ZNF74; NFAT5; KLF7; ZBTB39; HLF; HIPK2; ZFP37; MYOD1; ZNF354A; ATF6B; ZNF652; FUBP1; ZNF771; ZNF835; ZNF205; ZEB2; ZNF274; ZNF76; DYRK1B; HOXB3; ZKSCAN5; NFE2; GLI3; ZNF107; ZNF426; FOXJ1; CNOT3; ZNF544; KDM4C; ACTL6B; TFDP2; IKZF1; TLX3; RCOR3; FOXL2; SUPT5H; TXNIP; POU3F2; SPIB; NCOA2; E2F1; PITX2; SMARCA1; ZNF430; PITX3; ARID3A; YEATS2; ZNF510; NANOG; FOXC2; ZNF292; SIX3; ZNF3; TRPS1; ZFHX4; ARID4A; CDX1; EGR4; MYNN; VPS72; NFIC; UTF1; PHIP; TCF3; ZFX; ARL2BP; VAX2; EMX2; ZKSCAN7; HOXB2; ZHX2; TBX3; EHMT2; MED15; E2F8; CD3D; ZBTB6; MYCN; POU5F1B; ZNF83; NR0B1; TCF7L2; BARX2; ATN1; SMAD6; NFE2L2; TBX21; PRMT2; ZNF232; MYRF; MSX1; NFATC4; MBD4; SOX11; PAXBP1; KAT6B; ELF2; PEG3; CAMTA1; PNRC1; CDX2; WWC1; ARRB1; GON4L; HEY2; PRRX2; SIN3B; PCGF3; ZNF219; GFI1; ARID1A; EPAS1; AEBP1; DACH1; SP140; MAF; JUP; JUN; ZNF432; GATA1; MYBL1; RORA; CCNT1; TCF15; TFEB; DBP; KLF11; ELF4; BACH2; SUPT4H1; STAT4; ZNF32; ZNF358; SOX13; ZNF589; ZNF202; LZTS1; MNDA; KAT2A; TFAP2C; HEY1; DAXX; CDK9; NR1H4; BAZ2B; SP100; ARNT; OSR2; TTF2; OLIG2; MED17; SALL1; TRIM24; ISL1; TAL1; NR1I2; BRCA2; SP140L; ZNF226; HMX1; ZNF532; CHD3; HOXB6; NKX2-2; HOXC4; ING3; ID2; ZNF512B; THAP10; SPDEF; TERF1; NFE2L3; ESRRG; GATA4; FLI1; E2F5; PBX1; LOXL2; RYBP; ZNF267; SOX10; PLAGL1; TOX; INSM1; EHF; FOS; ZKSCAN1; FOXA2; FOSB; ZNF189; SSBP2; HOXD11; CREB3; KMT2A; SMAD1; HTATIP2; DMTF1; PEX2; TCEA1; STAT5B; NKX2-1; TGFB1; MAFF; MITF; RBFOX2; PGR; AHR; SNAI2; NFATC3; FOXA1; NR1H3; INSR; FOSL2; EYA2; LITAF; BCL6; EGR3; KLF9; CITED2; IFI16; CALR; EGR2; ARNT2; ZNF22; TOX3; TBX2; SATB1; CREB1; FOXO4
Down-regulation 189 USP22; CCNA2; TCERG1; EZH2; MYC; HOXA5; ATF6; FHL2; RBBP4; NUP62; ADRB2; HDAC2; CDK7; ATF1; UBE2I; TRIM28; VGLL4; SNW1; DNAJC2; RAN; AATF; CTR9; SMARCE1; YBX3; NONO; TBP; TFDP1; DEK; MED6; TBPL1; TBL1X; FOXJ3; RBBP7; SSRP1; HNRNPD; ZNF146; BCLAF1; HDAC1; SMARCC1; CBFB; BAZ1A; RBM14; NCOA6; ATF4; NPM1; MLX; PA2G4; BRD8; HOXC6; CNOT1; NELFB; YBX1; CENPF; ENO1; FOSL1; XBP1; NRIP1; WWTR1; BAZ1B; BMI1; GTF2A2; TCF12; NCOA4; RUVBL2; HOXA10; KAT7; NACA; TP53; MBD2; ZFP64; CRK; MED1; ADNP; SFPQ; YWHAB; HSBP1; UBP1; HMGB3; RNF138; SF1; PUF60; JARID2; SMARCA5; CBX5; NFE2L1; SMARCD2; ZNF672; MAX; TRIP6; PTTG1; ITGB3BP; NCOR2; TOB1; BRD3; DDX54; CEBPZ; PRKDC; RNF6; SMARCA2; CTBP2; MTDH; CRY1; RFX5; XRCC6; CBX3; MED24; FOXD1; TRIM16; GATAD2A; VEZF1; RNF4; SAP30; CCDC59; BASP1; MAGED1; CCNC; ELF1; PATZ1; HMGB2; BATF3; NR2F2; TAF10; PPRC1; ASH2L; FLNA; TCF25; PMF1; ZMYM2; TCF20; RUNX1; PHF2; PIAS2; APEX1; SIX1; NKX3-1; DDX5; RBM39; KDM2A; TRIM32; REST; HDGF; C1QBP; SMAD2; TFAM; HMGB1; CXXC1; PRPF6; ZBTB38; PHF20; PITX1; PURA; POLR2A; PCGF2; STAT6; ECD; RREB1; SIAH2; TFCP2L1; ELK3; BRCA1; TRIM29; RRN3; ING2; SREBF1; MED4; HLTF; YAF2; EDF1; TBL1XR1; KLF2; ZBTB18; SUV39H1; HOXC10; IRX5; TSC22D2; IKBKAP; AFF1; SCAND1; ZBTB1; NFIB; KLF5; HIPK3; MTA1; HOXB7; ZFP36L1; KDM5D; ETS2; SOX9; MYB