Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16142 Cgp-60474 GSE70138 MCF10A Human 24h 1.11uM EID0005
Types Number Response transcription factors
Up-regulation 687 EGR1; ZNF586; PRDM14; MEF2C; HOXC8; ERBB4; HAND1; ARID5B; ZNF304; NCOA3; ZSCAN2; RFX1; GLI2; PAX8; CALCOCO1; HBP1; BARX1; NR5A2; ZNF606; RBPJL; RFX3; CBX2; ZBTB44; SALL2; CDIP1; EP300; TGIF2; ZNF331; EZH1; TBX6; ZNF467; ZNF154; TLX2; SOX17; MECP2; NR6A1; ESR1; LHX3; ALX4; ZNF671; MXI1; ZNF350; TWIST1; ZNF117; ZFP2; ZNF536; HOXA6; ZNF264; NEUROD6; PHOX2A; FOXE3; FOXP3; NEUROG2; ZNF500; PRDM5; EMX1; HES2; ZNF550; SOX21; TSHZ2; POU6F1; ZNF556; ZNF701; HIF3A; NFIX; POU6F2; SP4; LIN28A; PRDM1; SOX1; FEZF2; FOXH1; TBX5; ASCL3; PROP1; NR1I3; ZBTB48; ZNF221; ZIC3; SOX5; ZNF442; ZKSCAN3; HDAC5; THRB; CBX7; ZNF688; FOXL1; SCRT1; SOX18; HNF4G; IKZF3; ZNF136; HOXB8; ZFPM2; HOXD3; ZNF695; TAF1C; ZNF257; ZNF682; SSX7; HOXD12; CRX; PHOX2B; E4F1; NEUROG3; ZNF778; ESRRB; CDX4; PRDM9; ZFHX2; HEYL; NKX6-1; PRDM16; ZIM2; ETV3; ZNF814; ARID3B; PHF1; HOXB1; CIITA; HAND2; TBX10; ZNF667; NPAS1; WHSC1L1; SOX14; LMX1B; ZNF816; ZKSCAN4; GBX2; BRDT; TULP2; E2F2; ZNF549; ZNF250; TLX1; ONECUT2; HOXA3; ST18; ZNF696; AIRE; TEF; RORB; CHD2; BNC2; TUB; ZNF423; NOCT; SIX3; DLX6; MED12; ONECUT1; TBL1Y; NEUROG1; GSC2; TFDP3; SSX3; MAFK; FOXD3; TULP1; ZNF223; ZNF507; MED25; MXD4; TBX4; EYA3; GRIP1; SHOX; TFAP2B; GBX1; ZNF85; NRL; ZNF177; HNF4A; ZNF132; ZNF419; POU3F3; ZBTB3; ZNF91; ZNF268; SCAI; OVOL1; SIX5; PBXIP1; HSF4; ZNF345; ZNF75D; CIR1; NEUROD4; ZNF43; PAX2; SNAI1; LHX6; ZNF142; CREBL2; KMT2D; PRDM2; AFF3; HOXD1; STAT2; ZNF484; VENTX; IRF9; ZNF749; ALX3; EHMT2; LZTR1; MAPK8IP1; TAF6L; BAZ2A; ZNF623; MLLT1; NEUROD2; HESX1; TBR1; PAX7; AFF2; NFAT5; POU3F4; RFX2; HIC1; ZIC4; RING1; ATOH1; DYRK1B; ZNF768; ZNF613; NFKB2; GATA2; NR1H2; SRY; GRHL2; TCF21; POU1F1; GCM2; OVOL2; ZNF205; ZNF362; MEIS2; NR5A1; MECOM; ZNF532; CBX4; POU4F3; ZNF8; PNRC1; TONSL; KDM5C; SOX2; KLF13; PAX4; TCF4; ZNF80; MAP3K10; ATF2; MAML3; ZNF771; DOT1L; L3MBTL1; NKX2-8; ZNF135; AR; CBFA2T3; ZNF214; ZSCAN32; CEBPE; ZNF197; NCOA2; FOXB1; ETV2; BRWD1; ZNF415; TFDP2; PEX14; ZNF669; HINFP; ZKSCAN8; ZNF343; ATF6B; POU2F3; FOXJ1; PPARA; GLI1; ZNF471; SKI; ZNF224; ZNF208; ZNF254; IFNB1; HNF1B; NHLH1; SMARCA1; ZNF573; ZNF79; LHX5; NFE2; LDB1; ZNF211; DLX2; GFI1; ZNF407; LMO1; ZNF440; ZNF780B; ZNF674; FOXI1; NKX2-5; RXRG; TP73; ZNF157; ZSCAN9; SCMH1; ZNF611; ZNF460; ZNF562; ASCL2; MYF5; ZNF235; ZNF81; RARG; VHL; ZNF174; ESR2; TCEA2; LBX1; RAX; PPARD; SOHLH2; ZBTB7B; ZNF665; CARF; PDX1; ZNF391; EBF2; TLE2; ZNF33B; ZNF175; ID4; MSX2; CBFA2T2; SUPT6H; SSBP3; MEOX2; GATA1; TTF2; ARL2BP; ZNF239; RUNX2; TFAP4; SOX3; FOXD2; ZNF180; TLX3; MAK; ZNF141; E2F4; ZSCAN18; NFIC; SPI1; ZNF41; PRDM8; ZNF492; CERS4; CCNE1; NKX3-2; POU2F2; BCL11A; ZNF552; ASH1L; ZNF93; THRA; BARX2; ZNF155; DCC; ZNF544; IKZF4; EVX1; KLF15; DLX5; DBP; ZNF225; THAP9; SIX6; WWC1; NFKBIB; ZBED2; CIC; TERF1; EPAS1; ARHGAP35; ZNF76; ZNF234; PITX3; HNF1A; HOXC5; PAX1; PAX3; FOXN3; ZNF253; VSX1; NAB2; POU5F1B; NACA2; LITAF; ATF7; HMBOX1; WNT4; ZNF770; ZNF287; ZNF133; SRCAP; JUN; GFI1B; ZNF165; PKNOX2; PRDM12; MZF1; TAF7L; CREB3L2; TXNIP; ACTL6B; ARRB1; ZNF444; CDX1; MED31; ZXDB; GCM1; ZNF493; ZNF134; DLX4; BNC1; MYEF2; APBB1; HDAC9; MYOD1; HOXD9; FOXN1; NEUROD1; UTF1; HOXD13; FOXE1; CRTC1; ARNT; ZBTB7C; HOXA2; E2F1; ZNF506; MSC; ZNF74; ZNF124; FOXF1; ZNF112; TBX19; CD3D; CSDC2; REL; MEIS1; ZNF480; ZNF329; FOXL2; ATF3; SLC2A4RG; TCF3; VAX2; LHX1; ZNF34; SUMO1; SOX12; ZNF184; HMGXB3; GATA6; TBX1; MYT1; POU3F2; CAMTA2; HLX; WT1; HMGA2; ZNF551; KLF8; TAF1; CDX2; VGLL1; MED15; SUPT3H; ZNF510; NHLH2; HOXB3; ZNF140; ZNF219; POU4F2; NR2E1; ZNF710; MYF6; SOX11; PBX2; MDM4; ZNF148; TFAP2A; ZNF571; CITED2; FHL5; ZNF835; NR0B2; IKZF1; LZTS1; E2F8; ZNF248; NANOG; HLF; PRDM10; TBX21; SETDB1; SMAD6; ZNF358; EN2; HOXB5; CUX2; ZFP69B; IRF6; HOXA4; ZNF675; NR4A2; ZFY; MEOX1; DMRT1; MYCL; NFATC4; TFEC; SIM1; HHEX; SHOX2; ARID3A; ZBTB17; E2F5; YBX2; ZNF589; ZNF10; ZNF654; SKIL; NFE2L3; ING4; ARID5A; CALR; MED14; ZNF711; ZNF14; KLF7; PAX9; SPIB; FOXC2; RARB; PROX1; CHD3; MXD3; MYCN; RBL2; YAP1; MYRF; LMCD1; HIVEP1; ZNF426; IRF5; CBX6; KDM4C; MBD4; TEAD3; CREB5; RSF1; ZNF200; ZNF131; BANP; TULP3; ZNF334; CNOT3; ZNF12; MLLT10; GLI3; NKX2-1; KAT6B; PEG3; ZNF529; MNX1; ZNF557; VPS72; MDM2; HIPK2; RORC; DAXX; ZSCAN31; ZNF44; TBX3; ZFX; TRIM24; ZNF273; TRPS1; RBPMS; NFATC1; BACH1; PRRX2; NR1H3; LHX2; ISL1; ING1; ZNF217; ZNF354A; FOS; TCF15; RORA; NR2F1; THAP10; FOXA2; PITX2; HOXC4; IL16; STAT4; CSDE1; ZFHX4; ARID1A; WWP1; HMX1; KLF11; ZKSCAN7; TOX; SPDEF; ZSCAN16; ZNF232; LOXL2; NR1H4; SSX1; GATA4; SSBP2; ZEB1; BHLHE41; ATN1; TRIB3; SMAD1; ZNF652; HOXB13; ZNF430; AEBP1; NR4A3; TGFB1I1; ZNF512B; PAX6; FOXA1; TCF7L1; OSR2; BRD4; IRF4; KAT2B; RBFOX2; IRF1; KLF9; HEY1; PBX3; EYA2; MNDA; IRF7; FOXF2; FOXG1; FLI1; CRYM; CREM; HEY2; ZBTB20; JUP; PTRF; DACH1; NR4A1; NKX2-2; TAL1; TGFB1; ARNT2; FOSB; POU2AF1; MAF; PBX1; TGIF1; EMX2; ZNF22; TOX3; NFATC3; HOXB6; TSC22D1; TFAP2C; FOXO4
Down-regulation 203 USP22; CCNA2; MYC; TCERG1; FOSL1; ADRB2; CRK; NUP62; VGLL4; HOXA5; NFKBIA; HDAC2; FHL2; EZH2; SNW1; BAZ1A; RAN; YBX3; ATF1; DNAJC2; DEK; CDK7; RBBP4; SFPQ; UBE2I; AATF; KAT5; NRIP1; MBD2; RBM14; NELFB; NFIL3; SMARCE1; CENPF; NPM1; NACA; MLX; ATF6; SMARCC1; PTTG1; TBP; NCOA4; BMI1; ZNF672; HSBP1; ZBTB11; ATF4; VEZF1; YBX1; GATAD2A; BCLAF1; TLE1; ELF1; TMF1; RBBP7; CTR9; MED1; XBP1; RNF6; KAT7; CEBPG; HNRNPD; TRIM28; BAZ1B; DR1; PA2G4; ZNF146; RUVBL2; EED; NR2F2; HOXC6; JARID2; HOXA10; NKX3-1; DDX5; TP53; RNF138; CBFB; FOXM1; CCDC59; HOXB7; MED24; PUF60; PRKDC; PATZ1; REXO4; RNF4; TSC22D2; DDX17; YAF2; BTG1; BRPF1; TRIM29; ASXL1; NCOR1; HSF2; ARID4B; SSRP1; MED6; CENPB; TAF10; DDX54; CEBPB; SMARCD2; CARM1; TBL1XR1; BRD3; CTCF; XRCC6; UBP1; SMARCA2; CRY1; RFX5; CBX5; PURA; SMARCA5; ERBB2; NONO; SF1; PHF2; STAT6; TTF1; TRIM32; CTBP1; CEBPZ; CNOT6; ZBED4; RBM39; ADNP; CCNC; ZBTB24; HMGB2; BCOR; ENO1; NPAS2; PPRC1; SMAD3; YWHAB; BIRC2; PMF1; ZMYM2; FLNA; ZFP36L1; IFI16; ZBTB1; NAB1; MTDH; CHD7; RRN3; BHLHE40; FOXD1; KDM2A; MED21; MEF2A; APEX1; BRCA1; ASH2L; SAP30; TFAM; ECD; ITGB3BP; NCOA6; SIM2; BATF3; EDF1; KLF4; BLM; ILF2; ING2; TCF12; TOB1; MYBL2; TRIM16; ARNTL; SUV39H1; NFKB1; BRD8; JUND; CREB3L1; CREB3; AGO2; ETS2; HLTF; HDGF; SCAND1; IKBKAP; FOSL2; ELK3; RREB1; SUB1; HMGB1; KLF5; NCOR2; HMGB3; ASCL1; MAFB; KDM5D; HOXC10; KLF10; BASP1; MAGED1; ZIC1; STAT5B