Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16141 Cgp-60474 GSE70138 MCF10A Human 24h 3.33uM EID0005
Types Number Response transcription factors
Up-regulation 631 PPARD; EGR1; RFX1; AR; NR1H2; ERBB4; THRB; LIN28A; CDIP1; EP300; TWIST1; GLI2; ZNF816; RFX3; CREB3L2; ZBTB48; BARX1; ARID5A; TBX6; HDAC5; SPI1; E2F2; ZNF136; ZNF154; FOXH1; SOX17; HIF3A; PRDM9; PHF1; RBPJL; ALX4; ZSCAN2; CIITA; LHX3; HAND1; NR6A1; SHOX; FOXE3; ZNF667; CAMTA2; CALCOCO1; NR5A2; MEF2C; HES2; ZBTB44; ZNF117; ZNF536; ZNF254; PRDM16; LMX1B; ZNF506; ASCL3; TBX5; POU6F2; SALL2; PRDM14; ESRRB; LZTR1; ZNF682; ZNF550; SCAI; FEZF2; REL; ZNF442; ZNF257; NEUROG2; ZIC3; ZFP2; SOX5; HBP1; ZNF440; SOX1; WHSC1L1; ZNF331; HOXD12; FOXL1; NR5A1; ZNF586; ZNF701; CRX; CDX4; TEF; SKI; ATF6B; IKZF3; HOXA6; ZNF221; PRDM2; GRHL2; SOX3; ATOH1; DOT1L; HOXB8; ZNF85; ZNF749; NACA2; POU6F1; ZNF814; ZNF611; ZNF484; ZNF471; ZNF250; GRIP1; NEUROG3; ZNF671; PRDM1; ZNF549; ZNF391; ALX3; ZSCAN9; SCRT1; RING1; ZNF345; ZKSCAN8; HOXB1; ESR1; MECP2; ZNF500; ZNF695; GSC2; ZNF268; DLX6; ZNF208; SUPT5H; MDM4; ZNF350; HNF4G; BRDT; ZKSCAN4; ZNF665; TLX1; AFF2; IKZF2; TFAP2B; HIC1; L3MBTL1; AFF3; POU1F1; ZIC4; SOX18; TLX2; SRCAP; KMT2D; ZNF75D; MAML3; SSX7; TULP2; ZNF362; HINFP; HLX; ZNF91; ETV3; LBX1; EMX1; MAFK; SP4; KAT2B; CEBPE; ZNF43; PBXIP1; HOXC8; ONECUT1; NEUROD6; ZNF573; PAX3; AIRE; NFIX; NEUROD4; MED25; PRDM12; POU2F3; HAND2; ZNF688; NOCT; TBX1; SOX14; ARID5B; ZNF467; POU3F3; TGIF2; ZNF80; HNF4A; ZNF223; PHOX2A; FOXD3; ZNF132; ESR2; VENTX; OVOL1; KLF8; ZNF623; RORB; E4F1; NPAS1; ZNF235; CARF; TCF21; ASCL2; ZNF675; GCM2; HDAC9; TBL1Y; ZNF224; THRA; NR4A3; ZNF415; ZFHX2; GATA3; ZNF780B; ZNF407; LMCD1; SUPT3H; GBX2; PROP1; ZNF253; ZSCAN18; GFI1B; ZNF493; STAT2; ZNF157; ING4; TUB; POU4F3; ZNF507; HOXD3; MLLT1; ZNF142; TBX10; NR2E1; FOXB1; PAX4; ZNF264; MAPK8IP1; ZBTB3; VSX1; LITAF; TULP1; STAT4; HESX1; NEUROD2; PDX1; FOXD2; TBR1; ZNF44; TBX19; RFX2; ZNF674; ZKSCAN3; ZBED2; ZNF81; NR1I3; SOX21; SIM1; ZNF571; ZNF107; MSX2; PAX7; NFKB2; HOXA3; ZBTB7C; NKX6-1; UTF1; ZNF606; ZNF835; DLX5; ZNF225; VHL; ZNF155; ZNF214; CBX7; CDX1; SRY; THAP9; CBX2; EYA3; CHD2; PLAG1; BNC2; ZXDB; GBX1; ZIM2; ZNF562; ZNF165; NFIC; PRDM10; MXD4; IRF9; ZNF710; KLF13; ATF2; ETV2; NRL; FOXN1; HEYL; RORA; DCC; TBX21; TFDP2; SSX3; ZFY; VGLL1; TBX4; MAK; FUBP1; TSHZ2; ZNF669; TFDP3; SOX2; ZNF304; MYEF2; ZBTB7B; PAX1; OVOL2; ZNF79; SIX5; ZNF556; NEUROG1; SUPT7L; MYF5; IRF6; BNC1; ZNF180; ZNF654; ZNF334; TAF6L; ZBTB17; NKX2-8; EZH1; CREM; ARHGAP35; ZNF41; FOXP3; ZNF770; POU5F1B; ZNF174; HHEX; ZNF234; WNT4; ZNF532; POU3F4; SIX6; PRDM8; GLI1; ONECUT2; ZNF287; KDM4C; MED31; PPARA; ZNF273; SCMH1; SHOX2; CBX4; TCEA2; GATA6; NR0B2; POU2F2; ZNF492; IKZF1; THAP3; ZNF768; MEIS2; TONSL; ZNF140; NEUROD1; TEAD3; ZNF135; ZNF419; ZNF613; TAF1C; MECOM; ZNF468; CUX2; ZNF426; HMGA2; GFI1; ZFPM2; ARID3B; FOXF1; DMRT1; ZNF329; CBFA2T3; ATF7; CDX2; LZTS1; CERS4; PNRC1; ZNF652; ZNF771; SP140; ZNF76; DYRK1B; SNAI1; EHMT2; ZNF239; MYT1; HNF1A; CREB5; SOHLH2; MAP3K10; SP140L; BRWD1; NFAT5; MXI1; NKX3-2; MZF1; NKX2-5; HNF1B; RXRG; CD3D; CREBL2; ARNT; ZNF423; TP73; SKIL; ZNF711; HSF1; PRMT2; RARG; PKNOX2; ZNF529; FHL5; ZNF141; TCF4; VAX2; MXD3; HIC2; NR0B1; BCL11A; PEX14; RNF2; HABP4; ZNF528; ZNF10; ARID3A; TLX3; MKL1; FOXI1; IRF3; RCOR3; DBP; NHLH1; FOXE1; PBX2; FOXJ1; ZNF222; KLF15; DLX4; HOXC5; ZSCAN32; TAF7L; GCM1; ZNF215; LHX6; RAX; FOXL2; SMARCA1; ZNF93; ZBTB32; HOXA2; NFATC4; MEIS1; ZNF205; ZNF177; ACTL6B; ZNF551; HOXB5; CIR1; TFAP2A; PHOX2B; MBD4; SSBP3; YEATS4; HOXD13; EBF2; SUPT6H; TCF7L1; TSC22D3; ZNF552; HMBOX1; PRDM13; ARL2BP; ZFP37; ZNF358; HOXD9; E2F5; HSF4; KAT2A; NKX2-1; TRPS1; ZNF34; ZSCAN16; RBL2; RORC; MYNN; GATA1; LDB1; TXNIP; MYCN; HIVEP1; NR4A1; NANOG; HIPK2; MDM2; SUMO1; BACH2; SP100; ZFP30; TTF2; MEOX2; TRIM24; KLF7; NHLH2; SIX3; CERS6; WWC1; TOX; ST18; GATA2; ZNF580; ZSCAN31; ZNF74; THAP7; ATN1; KDM5C; EN2; PITX3; EVX1; FOXA2; TGFB1; ZMIZ1; LOXL2; PITX2; ELF4; POU3F2; ZNF248; WT1; ZFP69B; PLAGL1; ARRB1; EMX2; TFEC; TULP3; ZNF444; OLIG2; ZNF544; ZNF112; ZNF195; TAF11; CCNE1; NCOA2; ZFHX4; HEY2; YBX2; SIN3B; NR3C2; NFE2; MED14; ZNF226; BRD4; TAF1; RSF1; FOXN3; ZNF124; AEBP1; SMAD6; PEG3; PEX2; MYCL; FOXF2; HOXD1; WWP1; PIAS4; DACH1; PSIP1; ZNF589; MED15; SOX10; E2F8; CALR; ESRRG; INSR; ZKSCAN7; CNOT3; ZHX2; FOS; SALL1; ZNF83; NR4A2; AES; INSM1; SPDEF; MYBL1; HEY1; BBX; DLX2; VPS72; ETS1; HTATIP2; OSR2; ATF3; KLF11; JUP; HLF; ID4; MSX1; NR1D2; MEOX1; PGR; ARNT2; PRRX1; PAX6; ETV5; ASCL1; NKX2-2; ID3; NR1H4; TGFB1I1; MYRF; TRIB3; SOX11; SSBP2; NFATC3; EHF; FLI1; TBX3; ZIC1; SSX1; CRYM; MAF; SNAI2; LEF1
Down-regulation 209 CCNA2; MYC; USP22; NFKBIA; CRK; FOSL1; HOXA5; TCERG1; ADRB2; FHL2; NUP62; TBP; UBE2I; HDAC2; CDK7; RBBP4; TBL1X; RBM14; CTR9; SNW1; ATF1; DNAJC2; ATF6; TRIM28; NRIP1; CENPF; BAZ1A; HOXA10; MED6; EZH2; NKX3-1; AATF; MBD2; BCLAF1; RAN; SFPQ; RNF6; NCOA4; ECD; TP53; HNRNPD; SMARCE1; ADNP; NFIL3; ATF4; SMARCC1; ZNF473; NCOA6; HOXC6; PATZ1; BRD3; CNOT1; PA2G4; SMARCA5; ZBTB11; ZNF146; SAP30; NPM1; SMAD1; ELF1; CTCF; RUVBL2; REXO4; ZMYM2; RNF4; MED1; NR2F2; CCDC59; YBX3; CENPB; TRIM27; RUVBL1; DDX54; PPRC1; ERG; NACA; HOXB7; ZFP64; KAT7; TCF20; MLX; ZBED4; UBP1; CNOT6; TSC22D2; NPAS2; XBP1; ZBTB24; HMGB2; ZNF672; MAX; EED; DDX5; TAF4; ILF2; CBFB; BAZ1B; NPAT; HCFC1; NFYA; BRD8; KLF10; XRCC6; PHF20; YWHAB; BASP1; SOX9; NELFB; TRIM32; RNF138; HMGB1; WHSC1; APEX1; MTDH; BRPF1; TCF12; BMI1; DDX17; ELK3; DEK; TAF5; PRKDC; NFKB1; VEZF1; NONO; PLAGL2; CEBPZ; JARID2; PTTG1; TRIM29; RNF111; CBX3; RREB1; IRF2; PBRM1; CBX5; C1QBP; SSRP1; PRPF6; CRY1; RBM39; TRIP6; MED17; CEBPB; SCAND1; NFE2L1; ZBTB18; HMGB3; MEF2A; STAT6; HSBP1; COPS2; PUF60; AFF1; SMAD2; ETV4; SMARCD2; FOXC1; ING2; ITGB3BP; BHLHE40; SUV39H1; ENO1; TBL1XR1; MYBL2; ARID4B; BLM; IKBKAP; YAF2; SP3; KDM2A; BRCA1; NFYB; ZNF410; MAGED1; PURA; KLF6; REST; ZNF443; HOXC10; RCOR1; HDGF; RBPJ; SUB1; IFI16; TRIM16; GATAD2A; SMARCA2; KLF5; MED24; ETS2; BTG1; ERBB2; BATF3; PCGF2; EDF1; KLF4; CTBP2; BCL11B; NFIB; TOB1; NCOR2; KLF2; ZFP36L1; PIR; ID1; TSC22D1; MAFB; MYB