Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16137 Nvp-aew541 GSE70138 MCF10A Human 24h 1.11uM EID0005
Types Number Response transcription factors
Up-regulation 60 KDM5A; TSC22D3; NR1H2; IRF7; ZNF24; VGLL4; MECOM; SOX9; ATF4; PHIP; CAPN15; AES; CEBPD; FOSB; BASP1; FLNA; JUNB; ZMYND8; ZIC1; WWTR1; JUND; KLF2; ELF4; MEIS1; DDX5; TSC22D2; ZNF83; PIAS3; CTNNB1; ZNF217; JUN; SMAD3; LOXL2; RBPMS; ZNF423; TGFB1; PBX1; FOXN3; ZNF415; TGFB1I1; ERBB2; EDF1; SCAND1; INSR; YWHAB; NFIB; HIPK1; CALR; MEIS2; TWIST1; SOX17; KLF4; ZFP36L1; BCL3; TRIM29; NR2F2; MNDA; FOS; MAFB; HMG20B
Down-regulation 31 CCNH; MKL2; RCOR3; SP140L; ITGB3BP; PAX5; RYBP; HOXB2; SOHLH2; PMS1; CHD7; STAT4; CCNC; RNF14; PTTG1; VDR; TCEA2; ELF5; SMAD1; SUB1; TBX3; TGIF1; HMGB3; SSX1; SOX10; ZNF22; CREB1; TCFL5; LEF1; SATB1; KDM5D