Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16125 Gsk-1059615 GSE70138 MCF10A Human 24h 1.11uM EID0005
Types Number Response transcription factors
Up-regulation 278 TSC22D3; SOX4; HBP1; PNRC1; ZNF688; ZNF665; ZNF83; EP300; ZNF611; CEBPD; ARID5B; ZNF701; E2F2; L3MBTL1; ING4; ZNF33B; NCOA3; TFEC; ZNF350; HNF4G; BPTF; ZNF606; BCL6; INSR; ZNF573; ZNF467; ZNF268; ZXDB; ZNF440; GON4L; ZNF500; SPI1; ZNF250; ZNF135; NR1H2; ZNF446; ZNF160; THRB; PRDM9; MKL1; SOX3; ZBTB3; ZNF217; ZNF155; ATOH1; ZNF223; ZNF536; CARF; TXNIP; PCGF3; LIN28A; JUND; GLI2; CBX7; CREBL2; LHX3; ZNF43; SALL2; PRDM14; ZNF254; CIITA; CHD2; CALCOCO1; ZNF224; OSR2; ZNF471; ZNF749; ZNF814; PAWR; ZNF444; CSDC2; NAB2; ZNF345; BACH1; TRPS1; SIX3; NR1I3; FOXN3; BRWD1; ZNF157; ZNF214; SOHLH2; TCEB2; IRF9; ONECUT2; POU1F1; ZNF768; ZNF580; TSHZ2; ZNF81; NR1H4; FEZF2; TRIM22; NR5A1; LZTR1; HIF3A; ZNF362; TBX1; SOX18; VENTX; SP1; MAML3; TBL1X; HDAC5; ZSCAN9; ZNF117; ERF; ZNF225; ZNF682; DLX4; CUX2; ZNF623; POU2F3; DAXX; TCF7L2; NFATC1; ZNF34; SOX2; ZNF675; ZNF93; CDIP1; PKNOX1; SOX5; MAF; MYF5; ZFP36L2; REL; SCAI; PRDM2; KLF3; ZNF91; ZNF132; NPAS2; TCEA2; ZNF667; KLF11; ZNF257; TLE2; ZNF80; HOXD13; POU4F2; ZNF334; PBXIP1; ZNF112; ZNF331; CERS4; ZNF674; HOXB1; NFE2; NCOA2; HESX1; ZHX2; ZNF175; RORC; ZNF85; ZNF253; MED25; ZMIZ1; ZNF75D; PHIP; HLX; THRA; MYRF; ZSCAN31; ZFPM2; ZIC3; HOXD3; BAZ2B; ZBTB20; MNT; ZMYND8; OLIG2; SALL1; FOXA1; VGLL1; BASP1; ZNF654; PBX1; ZNF141; ZBTB16; TCF7L1; TRIM24; SIX6; ZFP36L1; DDX17; SRY; ZNF358; WNT4; SOX11; PHF20; ZNF721; OVOL2; ZNF415; ERBB2; SOX17; IRF6; NR5A2; SSBP3; GATA6; JUP; ZNF544; GRHL2; ESR1; PEG3; ERBB4; EN1; TLE4; FOXO1; TGIF1; ZKSCAN1; MEIS1; TFDP2; HOXD1; CUX1; ZNF165; HOXB13; JUN; TWIST1; KAT2B; WT1; HLF; FOXF2; ZNF302; CREB5; AEBP1; HOXC4; HDAC4; TULP3; MEOX2; KLF5; HHEX; BNC2; ID4; CBFA2T3; NANOG; BTG1; TGFB1I1; MEOX1; TAL1; EMX2; NFATC4; AHR; TOX3; TRIM29; ZNF264; NR1H3; ARNT2; RBFOX2; IRF8; KLF4; TFAP2C; TRIB3; SMAD1; LMCD1; ZSCAN18; FLI1; ZNF512B; ST18; HEY1; MYCN; HIC2; SCAND1; DLX5; SSX1; TBX3; TCF4; INSM1; FOSL2; EHF; ZIC1; SNAI2; MNDA; FOS; CRYM; VPS72; MAFB; BHLHE41; FOXO4
Down-regulation 85 CCNA2; FOSL1; GTF2A2; DRAP1; BMI1; ADRB2; MYCBP; CTR9; EED; HDAC2; EGR1; TBP; EZH2; NRIP1; RUVBL1; TCERG1; MLX; SF1; PSMC3IP; ETS1; CCNE1; NUP62; CRY1; ASH2L; CCNC; CHD7; HSF2; BCLAF1; RBM14; RNF6; XBP1; HOXA1; CCDC59; NPM1; MYBL2; FOXD1; RAN; SFPQ; ENO1; GABPB1; RBBP4; KDM2A; C1QBP; BHLHE40; FOXC1; HNRNPD; SUB1; ING3; ELK3; EYA2; SMAD7; JUNB; CALR; BATF3; PIAS2; COPS2; PRKDC; STAT1; ZBTB18; DNMT3B; STAT5A; HLTF; MTDH; HMGA1; MYB; KLF2; IRX5; CEBPZ; MAGED1; HMGB1; EGR3; STAT3; CBFB; SERTAD2; LEF1; PIR; PURA; SATB2; PITX1; SUV39H1; HOXB7; STAT5B; CREB1; TCFL5; SATB1