Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16123 Gsk-1059615 GSE70138 MCF10A Human 24h 10uM EID0005
Types Number Response transcription factors
Up-regulation 611 TSC22D3; CALCOCO1; EZH1; HBP1; GATA3; NR1H2; ZNF671; PNRC1; ZNF688; PRDM2; CBX7; HDAC5; HDAC6; ZNF133; ZNF211; CAMTA2; MZF1; SALL2; BAZ2A; ZNF768; PBXIP1; CBFA2T2; RING1; ZNF500; IRF9; HINFP; ZNF419; ING4; LHX3; PRDM14; NRL; PPARA; ZNF304; RORA; RFX1; ZXDC; FOXH1; CEBPD; BACH1; ZBTB48; SETDB1; THRB; ZNF83; IRF8; MECP2; WNT4; SRCAP; ZNF506; GLI2; ZNF467; CSDC2; ZNF701; CIITA; TAF1C; GATA1; CDIP1; TCEA2; ZNF33B; ZNF154; FOXN3; GFI1B; ZNF337; ZBTB43; JUND; ZIC3; KLF1; ZNF586; ZHX2; TULP2; HOXC8; ASCL3; POU6F1; TCF4; VENTX; SKI; BPTF; SOX17; ZNF611; RBPJL; ZNF778; ZNF224; ALX3; MEF2C; TSHZ2; ATOH1; TULP1; LIN28A; PAX6; CBFA2T3; ZSCAN32; ZNF665; TBX4; ZNF510; CRX; ARID3B; BARX2; KLF13; BTG1; DLX4; SOX2; TBX19; ZNF444; NR5A1; CRTC1; ETV2; GRIP1; NR1I3; TLE2; ZNF175; PRDM1; EP300; NCOA2; LZTR1; SIX3; SOX13; CIR1; ZNF177; NR6A1; ZNF180; PPARD; ARID5A; RFX2; NKX2-5; SSBP3; LMO1; SOX21; ZNF345; ZSCAN9; DYRK1B; NCOA3; SOX4; TBR1; ZNF76; MDM4; HIF3A; POLR3C; ZSCAN2; ZNF711; ZNF8; ZNF132; CBX2; NEUROG3; RARG; MBD4; TEF; TFEB; BRWD1; ID4; ZKSCAN8; ERBB4; RFX3; ZNF669; HDAC11; POU2F1; SALL1; OVOL1; ZBTB7B; ZNF264; ZNF816; GBX2; GON4L; FOXL1; PHIP; FOXB1; TADA3; ZNF75D; ZNF117; SUPT4H1; NEUROD1; ZNF814; TFE3; FOXN1; CHD2; E4F1; ZFP2; ZBTB3; ZNF223; ZNF549; POU6F2; ZFHX2; ZNF85; ZNF136; HESX1; NKX3-2; RORC; PRMT2; ZNF43; CERS4; STAT2; APBB1; ZXDB; TEAD3; HDAC9; ZNF134; BCL6; ZNF235; SIX5; HSF4; ZNF667; TBX5; VGLL1; KLF15; L3MBTL1; THAP3; SIN3B; LMX1B; SCRT1; OVOL2; YBX2; KAT2B; ZNF442; KLF11; PLAG1; PRDM9; NR2E1; GSC2; CUX1; SUPT5H; ZNF507; TBX21; ZNF91; HOXB1; TXNIP; TRPS1; PCGF3; TFAP2A; TAF6L; SIRT2; SUPT6H; THRA; MLLT1; FEZF2; MED31; SOX5; MLXIPL; SP4; CBX4; ZNF34; RAX; CDX4; TULP3; TLX3; PEX14; ZNF571; ZNF79; GBX1; ARNT; PAX9; POU5F1B; ZNF253; ZNF787; FOXO3; EMX1; ZNF391; PPP1R13L; RBPMS; AFF3; ZBTB44; ZNF225; NEUROG2; ZKSCAN7; IKZF1; ZNF550; IKZF3; PAX1; DBP; ZNF282; HOXD12; FOXD3; NFE2L2; SRY; GCM1; IFNB1; NHLH1; ATF6B; MAPK8IP1; ZNF273; PKNOX2; NEUROD6; POU3F3; SOX14; NFKB2; TP73; ESRRB; ZNF771; ZNF219; GFI1; FOXE3; ZNF135; ZNF155; MAFK; HNF1B; MAP3K10; ZNF343; ZNF536; HLX; PAX7; HIC1; KDM4C; CIC; IL16; ZKSCAN4; MED16; ZNF835; JAK2; CREBL2; MED25; ZNF695; PRDM8; TFDP3; SOX18; SIRT7; BCL11A; KLF8; ZNF212; ZNF446; ESR2; HNF4A; HNF1A; FOXA2; POU2AF1; NEUROG1; NEUROD4; ZNF257; TLX1; BAZ2B; ELF2; AR; AIRE; ZNF749; SPI1; DCC; ETV3; ZFPM2; NPAS1; MAML3; SHOX2; SCAI; ZNF362; TLE4; CENPB; FOXF2; INSR; TFDP2; SIX6; BACH2; POU2F2; ZBTB39; ZNF254; BNC2; ST18; MEIS1; MEF2D; DLX5; ZNF675; FOXO1; POU1F1; ETV7; HNF4G; ZNF14; PAXBP1; PRDM12; PHF8; ZNF407; HEYL; PIAS4; ZNF141; ONECUT2; KLF9; NANOG; MXI1; ZNF208; ZEB1; DOT1L; ZNF205; LHX1; ZNF329; ZNF174; CIZ1; ZBTB20; TGFB1; NFE2; ZBTB17; CARF; ZNF354A; BCOR; PDX1; NEUROD2; ZNF682; NR1H4; SETD2; ONECUT1; MDM2; ZFY; CREB3L2; MEIS2; RARB; BRDT; VHL; HAND2; SUPT3H; BARX1; TAF7L; ZNF573; ZNF334; ZNF358; ZNF227; TCF7L1; ZIM2; XBP1; ZNF74; KLF3; ARL2BP; GCM2; SIAH2; EVX1; ZNF780B; LZTS1; TCF21; SNAPC4; ZNF408; ZNF629; ZNF493; CAMTA1; TCF3; SOX3; SKIL; HLF; ARID5B; RARA; TAL1; ZNF80; AEBP1; E2F2; SMARCA1; ZNF81; PKNOX1; OSR2; ZBTB16; PBX2; ZNF44; MYRF; ZSCAN16; NFIX; ZNF45; ZNF606; HIC2; PAX4; ZNF512B; NPAS2; NHLH2; HIPK2; ELF3; ZNF529; ESR1; CDK9; FOXC2; ARHGAP35; TCF15; DMTF1; PROP1; SMARCC2; ZNF131; RBL2; SMARCD1; ZNF107; FOXJ2; HOXA4; MAK; PHF1; POU4F3; ZNF415; UTF1; CNOT2; SAFB; RXRG; SOHLH2; ZNF551; ZNF423; RSF1; MXD3; ARID3A; RERE; TBX1; ZSCAN18; HCFC2; MKL1; ELF5; KLF7; CNOT3; NLK; ZNF587; KDM5B; ATN1; INSM1; ZNF394; FOXG1; ZNF492; TRIM22; NR5A2; ZNF350; NCOA1; GATA2; MKL2; PGR; TAF11; ZNF12; LMCD1; ZNF266; EPAS1; HEY2; MYCL; HIRA; TWIST1; TBL1X; ZNF589; CHD3; SMAD1; KDM5C; ZNF10; ZNF331; FOXE1; FLI1; RBPJ; EN2; IRF6; AES; ZNF248; ZNF623; ZNF217; REPIN1; ELF4; NFIC; ZNF160; SMARCD3; HMX1; ZIC1; ZNF165; ARID1A; HOXB2; HIPK1; SNAI1; NR1D2; IRF1; ZNF93; GRHL2; BRD4; SPIB; MED15; CSDE1; ACTL6B; DDIT3; HOXB13; MEN1; VPS72; STAT4; RXRA; PIAS3; FOXL2; CITED2; FOXO4; PAX5; TFEC; ZFP36L2; SOX11; JUP; MSX1; RYBP; EMX2; TBX3; ZBED2; MYBL1; ARID4B; SP2; ZNF232; MAFB; ERBB2; ZKSCAN1; RUNX1; CUX2; GATA6; KLF4; FOXF1; EN1; NFATC3; SPDEF; HOXD1; ZNF652; NFATC4; ARNT2; BCL3; CRYM; FOSL2; NFE2L3; MAF; PBX1; TRIB3; TOX; EHF; MEOX2; SSBP2; DACH1; MNDA; CITED1; HEY1; RELB; TBX2; STAT5B; TFAP2C; BHLHE41; KDM5D
Down-regulation 144 TFDP1; FOSL1; MYCBP; GMNN; HMGA2; FHL2; PARP1; USP22; RBBP4; RAN; ADRB2; MYC; GTF2A2; SFPQ; RUVBL1; ATF1; NPM1; CBFB; C1QBP; BAZ1A; TCERG1; ATF6; PCBD1; CCNA2; SMARCC1; SF1; EGR1; PSMC3IP; NUP62; HDAC2; PPRC1; PA2G4; ENO1; HSBP1; BRCA1; YBX1; DR1; TBPL1; ZBTB11; DNAJC2; IRX5; MTDH; ITGB3BP; RNF4; TRIM27; WWTR1; MYBL2; YWHAB; UBE2I; HNRNPD; SSRP1; MED6; ENY2; EGR3; NFIB; CTR9; HOXC6; RBL1; BMI1; TRIM28; MLX; PSIP1; MTF2; TBL1XR1; CTNNB1; DRAP1; URI1; SMARCA2; RBM14; EDF1; MBD2; TEAD1; HMG20B; PRKDC; NR2F2; RNF138; ZNF593; RNF6; WDR77; BCLAF1; HDAC1; TSC22D2; COPS5; MNAT1; TAF9; E2F3; DEK; ECD; TDP2; SMARCA5; AATF; NEDD8; GTF3A; TFAM; CNOT1; ELF1; PMS1; AFF1; CTBP2; DNAJC1; GABPB1; CNBP; EED; SAP30; ADNP; PUF60; FLNA; TAF10; TRIM32; RBBP7; SP110; HSF2; HOXC10; SMAD2; PIR; ZNF32; ERG; RREB1; MAGED1; KLF5; HMGB1; TOX3; JARID2; HES1; CHD7; LITAF; NRIP1; HMGA1; HMGB3; GATAD2A; EGR2; HOXB7; CENPF; CEBPZ; KLF6; STAT3; ZBTB1; JUNB; ETS2; ELK3; ID3; ZBTB18; ASCL1; TCFL5