Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16122 Barasertib-hqpa GSE70138 MCF10A Human 24h 0.04uM EID0005
Types Number Response transcription factors
Up-regulation 53 NR1H2; ZNF589; ISL1; ZNF611; TBL1XR1; MED14; FOSB; ZMYND8; LIN28A; SOX17; NAB1; BNC2; ID3; DLX5; TWIST1; JUP; IRF7; IRF9; JUND; TCF4; MTA1; SPIB; TCEA1; PRRX1; ZNF423; SMARCB1; ZFP36L1; TRIM22; BTG1; LOXL2; ESR1; IRF8; ID4; POU2AF1; PBX3; ID1; SNAI2; NANOG; MEIS2; EGR3; OSR2; TFAP2C; TGFB1; AEBP1; FOXF1; TGIF1; SPDEF; KLF4; TLE4; TRIM29; PBX1; BHLHE41; FOS
Down-regulation 20 BRCA1; ZNF443; NR2F2; ZNF266; RXRA; YBX3; ZBTB16; RORA; FOXC1; PURA; CD3D; FOXD1; TOX3; MAGED1; CREB1; NR2F1; STAT5B; BASP1; ZBTB18; SATB1